Results 161 to 170 of about 28,592 (236)

Oligomer-dependent and oligomer-independent pathogenesis of muscular dystrophy-associated mutations within the penta-EF-hand domain of calpain-3. [PDF]

J Biol Chem
Hisatsune C, Shinkai-Ouchi F, Hata S, Ono Y.   +3 more
europepmc   +1 more source

The N-Terminal Fragment of Urine Titin Is Not a Product of Degradation by Calpain 3. [PDF]

Muscle Nerve
Nambu Y, Matsumura T, Machida K, Tsutsumi R, Hata S, Shinkai-Ouchi F, Ono Y, Osawa K, Shirakawa T, Bo R, Nishio H, Sakaue H, Awano H, Matsuo M.   +13 more
europepmc   +1 more source

Variants in CAPN3 Causing Autosomal Dominant Limb-Girdle Muscular Dystrophy Combined With Calpain-3 Deficiency. [PDF]

Hum Mutat
Krag T, Nasho E, Brady L, Verebi C, Leturcq F, Malfatti E, Duno M, Tarnopolsky M, Vissing J.   +8 more
europepmc   +1 more source

Assessment of novel calpain inhibitors

, 2016
Calpains are intracellular Ca2+ -activated proteases and important mediators of the action of calcium. They are involved in numerous physiological and pathological phenomena, from embryogenesis to cell adhesion, diabetes, and Alzheimer’s disease ...
Baashirah, Azzah Ahmed
core  

Urinary N-terminal titin fragment ascertained as biomarker in a small cohort of limb-girdle muscular dystrophy LGMDR1-calpain 3 related. [PDF]

J Neuromuscul Dis
Valls A, Ruiz-Roldán C, Immanuel J, Camaño P, Poza JJ, Fernández-Torrón R, López de Munain A, Sáenz A.   +7 more
europepmc   +1 more source

Loss of Calpain 3 dysregulates store-operated calcium entry and its exercise response in mice. [PDF]

FASEB J
Villani KR, Zhong R, Henley-Beasley CS, Rastelli G, Harris E, Boncompagni S, Barton ER, Wei-LaPierre L.   +7 more
europepmc   +1 more source

Identification of novel pathogenic variants of Calpain-3 gene in limb girdle muscular dystrophy R1. [PDF]

Orphanet J Rare Dis
Banerjee S, Radotra BD, Luthra-Guptasarma M, Goyal MK.   +3 more
europepmc   +1 more source

Identification and functional characterization of a novel heterozygous splice‑site mutation in the calpain 3 gene causes rare autosomal dominant limb‑girdle muscular dystrophy. [PDF]

Exp Ther Med
Mao B, Yang J, Zhao X, Jia X, Shi X, Zhao L, Banerjee S, Zhang L, Ma X.   +8 more
europepmc   +1 more source

Calpain 3 and CaMKIIβ signaling are required to induce HSP70 necessary for adaptive muscle growth after atrophy. [PDF]

Hum Mol Genet, 2018
Kramerova I, Torres JA, Eskin A, Nelson SF, Spencer MJ.   +4 more
europepmc   +1 more source

Detection of Calpain-Mediated Beclin-1 Cleavage for Drug Discovery in Inflammatory Bowel Diseases. [PDF]

Cells
Hunter KA, Overstreet AC, Koff BB, Dharan H, Overend S, Messer JS.   +5 more
europepmc   +1 more source