Results 151 to 160 of about 28,592 (236)

Age, muscle, and gender specific characterization of muscle degeneration in a mouse model of calpainopathy

Scientific Reports
Establishing well-described mouse models of hereditary diseases is increasingly important for testing new therapeutic approaches, such as gene replacement therapy.
Nicolina Südkamp, Jacqueline Heinen-Weiler, Marlena Rohm, Michaela Zaik, Nassam Daya, Anne-Katrin Güttsches, Carsten Theiss, Andreas Roos, Tobias Ruck, Frank Jacobsen, Lara Schlaffke, Matthias Vorgerd   +11 more
doaj   +1 more source

Characterization of a new p94-like calpain form in human lymphocytes

, 2003
Human circulating PBMC (peripheral blood mononuclear cells) contain three calpain isoforms distinguishable on the basis of their Chromatographic properties. Two of these proteases belong to the ubiquitous calpain subfamily, corresponding to the classical
DE TULLIO, ROBERTA, MELLONI, EDON, STIFANESE, ROBERTO, SALAMINO, FRANCA, PONTREMOLI, SANDRO   +4 more
core   +1 more source

Calpain 3/p94 is not involved in postmortem proteolysis

, 2011
Studies on the correlation between expression and/or autolysis of calpain and postmortem proteolysis in muscle have provided conflicting evidence regarding the possible role of calpain 3 in postmortem tenderization of meat.
Geesink, Geert, Koohmaraie, M, Taylor, R G   +2 more
core  

The impact of chronic intermittent hypoxia on enzymatic activity in memory-associated brain regions of male and female rats

Biology of Sex Differences
Background Obstructive sleep apnea (OSA) is an intermittent hypoxia disorder associated with cognitive dysfunction, including learning and memory impairments.
Steve Mabry, Jessica L. Bradshaw, Jennifer J. Gardner, E. Nicole Wilson, Janak Sunuwar, Hannah Yeung, Sharad Shrestha, J. Thomas Cunningham, Rebecca L. Cunningham   +8 more
doaj   +1 more source

Developing fluorescence sensor probe to capture activated muscle-specific calpain-3 (CAPN3) in living muscle cells. [PDF]

Biol Open, 2020
Ojima K, Hata S, Shinkai-Ouchi F, Oe M, Muroya S, Sorimachi H, Ono Y.   +6 more
europepmc   +1 more source

Frizzled related protein deficiency impairs muscle strength, gait and calpain 3 levels. [PDF]

Orphanet J Rare Dis, 2020
Casas-Fraile L, Cornelis FM, Costamagna D, Rico A, Duelen R, Sampaolesi MM, López de Munain A, Lories RJ, Sáenz A.   +8 more
europepmc   +1 more source

The Influence of Caspase-3 on the Calpain Enzyme System During Meat Aging

, 2012
Tenderness is a key component of palatability, which influences consumers’ perception of meat quality. There are a variety of factors that contribute to variations in tenderness, including postmortem proteolysis.
Mohrhouse, D.A., Kern, S.A., Underwood, K.R., Weaver, A.D.   +3 more
core  

Calpain inhibition in a transgenic model of calpastatin overexpression facilitates reversal of myocardial hypertrophy

ESC Heart Failure
Aims It was recently demonstrated that the intracellular signalling phosphatase calcineurin is subject to cleavage by the protease calpain, resulting in a truncated calcineurin fragment that is a strong inductor of myocardial hypertrophy.
Gregor Sachse, Johanna Tennigkeit, Nikolaos Pagonas, Philipp Hillmeister, Ivo Buschmann, Martin Czolbe, Peter Nordbeck, Joachim Schmitt, Daniel Patschan, Oliver Ritter   +9 more
doaj   +1 more source

Effect of Ultrastructural Disruption and Protein Dispersion on Gel-forming in Myofibrillar Gels.

, 2007
Gelled muscle foods span a diverse range of products. The texture and water⁄fat binding properties of these food products is largely determined by their gel structure.
Wright, Bradley J
core  

Characterization of calpain 3 transcripts in mammalian cells : expression of alternatively-spliced variants in non-muscle cell types

, 2008
An investigation of the expression profile of mRNA encoding Calpain 3, the causative agent in the inherited human muscular disease Limb Girdle Muscular Dystrophy Type 2A, was conducted in two representative mammalian species, human and mouse ...
Dickson, James Michael Jeremy
core