Results 21 to 30 of about 6,565,578 (347)

The role of type 4 phosphodiesterases in generating microdomains of cAMP: Large scale stochastic simulations [PDF]

, 2010
Cyclic AMP (cAMP) and its main effector Protein Kinase A (PKA) are critical for several aspects of neuronal function including synaptic plasticity. Specificity of synaptic plasticity requires that cAMP activates PKA in a highly localized manner despite ...
Terrin, A., Terrin, A, Zaccolo Manuela, Rodrigo F Oliveira, Oliveira Rodrigo F., Kim, M., Blackwell, K., Cannon, R.C., Kim T Blackwell, Oliveira, RF, Wonryull Koh, Di Benedetto Giulietta, Kim MyungSook, Giulietta Di Benedetto, Manuela Zaccolo, Zaccolo, M, Cannon, RC, Terrin Anna, MyungSook Kim, Zaccolo, Manuela, Anna Terrin, Robert C Cannon, Di Benedetto, G., Cannon Robert C., Koh, K., Robert C. Cannon, Di Benedetto, G, Koh Wonryull, Zaccolo, M., Koh, W, Blackwell Kim T., Kim T. Blackwell, Rodrigo F. Oliveira, Oliveira, R.F., Kim, M, Blackwell, KT   +35 more
core   +2 more sources

Activation of myocardial cAMP‐dependent protein kinase by lysoplasmenylcholine [PDF]

FEBS Letters, 1997
Plasmalogen‐specific, calcium‐independent phospholipase A2 (iPLA2) is activated during myocardial ischemia. Accordingly, we have assessed the activation of myocardial protein kinases by the iPLA2 product, lysoplasmenylcholine. Lysoplasmenylcholine‐activated protein kinase activity from heart cytosol fractionated on a DE‐52 column was identified as cAMP‐
Williams, Scott D, Ford, David A
openaire   +2 more sources

Coordinated Control of Endothelial Nitric-oxide Synthase Phosphorylation by Protein Kinase C and the cAMP-dependent Protein Kinase*

Journal of Biological Chemistry, 2001
Endothelial nitric-oxide synthase (eNOS) is an important regulatory enzyme in the cardiovascular system catalyzing the production of NO from arginine. Multiple protein kinases including Akt/PKB, cAMP-dependent protein kinase (PKA), and the AMP-activated ...
B. Michell, Zhi-ping Chen, T. Tiganis, D. Stapleton, Frosa Katsis, D. Power, Alistair T. R. Sim, B. Kemp   +7 more
semanticscholar   +1 more source

Protein phosphorylation in yeast mitochondria [PDF]

, 1987
We describe the identification and submitochondrial localization of four protein kinases and of their target proteins in derepressed yeast mitochondria. The activity of one of the kinases depends on the presence of cyclic AMP (cAMP).
Günter Müller, Bandlow, Wolfhard, Wolfhard Bandlow, Müller, Günter   +3 more
core   +1 more source

GABAC-Receptor Stimulation Activates cAMP-Dependent Protein Kinase via A-Kinase Anchoring Protein 220

Journal of Pharmacological Sciences, 2008
In our previous study, anti-apoptotic effects of GABAC-receptor stimulation was suppressed by inhibitors of cAMP-dependent protein kinase (PKA), implying GABACreceptor–mediated PKA activation. The present study showed that GABAC-receptor stimulation with
Li Yang, Yasuhisa Nakayama, Naoki Hattori, Bing Liu, Chiyoko Inagaki   +4 more
doaj   +1 more source

Interacting protein kinases involved in the regulation of flagellar length [PDF]

, 2006
A striking difference of the life stages of the protozoan parasite Leishmania is a long flagellum in the insect stage promastigotes and a rudimentary organelle in the mammalian amastigotes.
Scholz, M., Melzer, I.M., Erdmann, M., Schmetz, C., Wiese, M.   +4 more
core   +4 more sources

Role of protein kinase C in cAMP-dependent exocytosis in parotid acinar cells

Japanese Dental Science Review, 2009
It is well known that β-adrenergic receptor activation in parotid acinar cells results in increased intracellular cAMP levels, and consequently induces exocytotic amylase release.
Hiroshi Sugiya, Keitaro Satoh
doaj   +1 more source

A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase.

Journal of Biological Chemistry, 1986
As an important new reagent for studying the cAMP-dependent protein kinase, a 20-residue peptide has been synthesized that corresponds to the active site of the skeletal muscle inhibitor protein.
Heung-Chin Cheng, B. E. Kemp, R. Pearson, A. J. Smith, L. Misconi, S. V. van Patten, D. A. Walsh   +6 more
semanticscholar   +1 more source

Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D [PDF]

, 2007
Phosphoinoisitide dependent kinase l (PDK1) is proposed to phosphorylate a key threonine residue within the catalytic domain of the protein kinase C (PKC) superfamily that controls the stability and catalytic competence of these kinases.
Kelly, April P., Cantrell, Doreen A., Wood, C. David, Matthews, Sharon A.   +3 more
core   +1 more source

Regulation of yeast phosphorylase by phosphorylase kinase and cAMP‐dependent protein kinase [PDF]

FEBS Letters, 1983
Yeast phosphorylase is phosphorylated and activated by a cyclic AMP‐independent protein kinase (called phosphorylase kinase) and a cyclic AMP‐dependent protein kinase. Only in the presence of both kinases is phosphorylase fully activated and phosphorylated.
Wingender-Drissen, Ruth, Becker, Jörn Ullrich   +1 more
openaire   +2 more sources