Results 251 to 260 of about 169,210 (304)

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

A unique role for cAMP signaling in microglia during opioid tolerance and withdrawal. [PDF]

Neuropsychopharmacology
Coffey KR, Neumaier JF.
europepmc   +1 more source

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

ESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad, Jeanne du Fay de Lavallaz, Michael J. Zhang, Thanat Chaikijurajai, Bo Ye, Prabhjot S. Nijjar, Julie A. Lahiri, Cindy M. Martin, Tamas Alexy, Markus Meyer   +9 more
wiley   +1 more source

Coupling thermotolerance and high production of recombinant protein by CYR1^N1546K mutation via cAMP signaling cascades. [PDF]

Commun Biol
Ren H, Lan Q, Zhou S, Lyu Y, Yu Y, Zhou J, Mo W, Lu H.   +7 more
europepmc   +1 more source

Researching Attitude–Identity Dynamics to Understand Social Conflict and Change

European Journal of Social Psychology, EarlyView.
Abstract Societies undergo constant change, manifested in various ways such as technological developments, economic transitions, reorganization of cultural values and beliefs, or changes in social structures. Individuals play an active role in shaping social and societal change by interactively negotiating its manifestation.
Adrian Lüders, Mike Quayle, Paul Maher, Ana‐Maria Bliuc, Pádraig MacCarron   +4 more
wiley   +1 more source

NEAT1 Deficiency Promotes Corneal Epithelial Wound Healing by Activating cAMP Signaling Pathway. [PDF]

Invest Ophthalmol Vis Sci
Sang T, Wang Y, Wang Z, Sun D, Dou S, Yu Y, Wang X, Zhao C, Wang Q.   +8 more
europepmc   +1 more source

Distinct methylome profile of cfDNA in AMI patients reveals significant alteration in cAMP signaling pathway genes regulating cardiac muscle contraction. [PDF]

Clin Epigenetics
Dash M, Mahajan B, Shah S, Dar GM, Sahu P, Sharma AK, Nimisha, Saluja SS.   +7 more
europepmc   +1 more source

Meet the Editorial Team. An interview with Angelo Iulianella, Assistant Editor, Dalhousie University Faculty of Medicine, Canada

Developmental Dynamics, EarlyView.
Paul Trevorrow, Angelo Iulianella
wiley   +1 more source

Fear memory regulation by the cAMP signaling pathway as an index of reexperiencing symptoms in posttraumatic stress disorder. [PDF]

Mol Psychiatry
Hori H, Fukushima H, Nagayoshi T, Ishikawa R, Zhuo M, Yoshida F, Kunugi H, Okamoto K, Kim Y, Kida S.   +9 more
europepmc   +1 more source

Point contact-restricted cAMP signaling control ephrin-A5-induced axon repulsion

Bécret J, Michaud C, Assali A, Chenais N, Kankadze I, Gomez-Bravo C, Roche F, Couvet S, Fassier C, Nicol X.   +9 more
europepmc   +1 more source