Results 101 to 110 of about 43,494 (228)

Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors. [PDF]

, 2014
BackgroundIn 31 solid tumor patients treated with the demethylating agent decitabine, we performed tumor biopsies before and after the first cycle of decitabine and used immunohistochemistry (IHC) to assess whether decitabine increased expression of ...
A Kumari, AS Yang, C Festuccia, C Zeller, CA Stidley, CJ Piyathilake, D Ma, D Matei, D Shang, DJ Stewart, DJ Stewart, DJ Stewart, DJ Stewart, DJ Stewart, DJ Stewart, DW Shen, E Gordian, E San Jose-Eneriz, EA Braga, F Crea, F Fang, H Iwata, H Kantarjian, H Kroeger, HM Kantarjian, J Charlet, J Shia, JA Plumb, JP Issa, JP Issa, JS Kim, K Ghoshal, K Onda, K Ramachandran, K Tikoo, KY Tse, L Ding, L Rothem, MA Kane, ML Orta, NH Nabilsi, R Zhao, RH Finnell, S Fu, S Vijayaraghavalu, SB Baylin, SS Muerkoster, T Tanaka, TB Lee, VF Chekhun, X Chang, XJ Liang, Y Li, Y Oki, Y Zhang, ZG Liu   +55 more
core   +2 more sources

Single Cell Multi‐Omics Reveals Rare Biosynthetic Cell Types in the Medicinal Tree Camptotheca acuminata

Plant Biotechnology Journal, EarlyView.
Van‐Hung Bui, Joshua C. Wood, Brieanne Vaillancourt, John P. Hamilton, Lemor H. Carlton, Thu‐Thuy T. Dang, C. Robin Buell, Chenxin Li   +7 more
wiley   +1 more source

Traditional Chinese Medicine Modernization in Diagnosis and Treatment: Utilizing Artificial Intelligence and Nanotechnology

MedComm, Volume 7, Issue 2, February 2026.
Traditional Chinese medicine (TCM) faces great challenges during the development of modern medicine. Utilizing novel technologies such as artificial intelligence (AI) and nanotechnology facilitates TCM with great potential in precision diagnosis and improved treatments efficacy.
Wenqi Yu, Mengzhen Chen, Xueqi Tan, Xi Wei, Fan Sun, Hua Yan, Xue Xu, Hongcai Shang   +7 more
wiley   +1 more source

M-polynomial and NM-polynomial indices of camptothecin–polymer conjugate IT-101 structure

Main Group Metal Chemistry
Camptothecin is a naturally occurring alkaloid known for its significant and selective inhibition of the topoisomerase nuclear enzyme, a critical target in cancer treatment.
Teng Ling, Zhang Lei, Abbas Muhammad Mohsin, Naeem Muhammad, Tchier Fairouz, Wang Yong   +5 more
doaj   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

Camptothecin-Loaded and Manganese Dioxide-Coated Polydopamine Nanomedicine Used for Magnetic Resonance Imaging Diagnosis and Chemo-Photothermal Therapy for Lung Cancer

International Journal of Nanomedicine, 2022
Mingliang Su,* Yukun Chen,* Lijun Jia, Zhanxia Zhang Cancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, People’s Republic of China*These authors contributed equally to this ...
Su M, Chen Y, Jia L, Zhang Z
doaj  

ETAA1 ensures proper chromosome segregation: A matter of S phase or mitosis? [PDF]

, 2019
ETAA1 activates the master checkpoint kinase ATR. Bass and Cortez (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201810058) recently reported an intra-mitotic function of ETAA1 that safeguards chromosome stability.
Achuthankutty, Bass, Bass, Feng, Haahr, Kabeche, Lee, Marina Alejandra González Besteiro, Miosge, Saldivar, Saldivar, Vanesa Gottifredi, Zhou   +12 more
core   +1 more source

The Role of Residual Hydrogen Peroxide for Biological Applications of Polymeric N‐Oxides

Journal of Polymer Science, Volume 64, Issue 2, Page 384-394, 15 January 2026.
Polymeric N‐oxides bind hydrogen peroxide with very high affinity. Therefore, residues of the oxidizing agent are difficult to remove from the polymers. This study shows that microbiological studies of polymeric N‐oxides can be compromised by these residues. Conflicting data on the antimicrobial properties of polymeric N‐oxides are therefore likely due
Michelle Kobus, Shirin Mesgarha, Erica Moretto, Jon Wullenweber, Mathias Ernst, Sebastian G. Wicha, Wolfgang Maison   +6 more
wiley   +1 more source

A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. [PDF]

, 2019
Elevated glucose consumption is fundamental to cancer, but selectively targeting this pathway is challenging. We develop a high-throughput assay for measuring glucose consumption and use it to screen non-small-cell lung cancer cell lines against ...
Chen, Bao Ying, Clark, Peter M, Damoiseaux, Robert, Ghezzi, Chiara, Ribalet, Bernard, Wong, Alicia   +5 more
core   +1 more source

Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B

Scientific Reports
Temperature is a vital environmental factor affecting organisms’ survival as they determine the mechanisms to tolerate rapid temperature changes. We demonstrate an experimental system for screening chemicals that affect cold tolerance in Caenorhabditis ...
Misaki Okahata, Natsumi Sawada, Kenji Nakao, Akane Ohta, Atsushi Kuhara   +4 more
doaj   +1 more source