GK PUA Domain Modulates Cables, Cooperativity, and Proline Feedback
EcGK tetramers hierarchically assemble into metabolic filaments and bundle into metabolic cables. Upon substrate binding, this dynamic equilibrium shifts from inactive cables to active tetramers to drive catalysis; meanwhile the inhibitor proline stabilizes an X‐shaped conformation, redirecting assembly toward filaments to enable efficient feedback ...
Tianyi Zhang +4 more
wiley +1 more source
Using sequence data to identify alternative routes and risk of infection: a case-study of campylobacter in Scotland [PDF]
<b>Background:</b> Genetic typing data are a potentially powerful resource for determining how infection is acquired. In this paper MLST typing was used to distinguish the routes and risks of infection of humans with Campylobacter jejuni from
Forbes, K J +45 more
core +1 more source
Campylobacter jejuni and Campylobacter coli
Definition of the disease: Campylobacter jejuni and C. coli can colonise the intestinal tract ofmost mammals and birds and are the most frequently isolated Campylobacter species in humanswith gastro-enteritis. Transmission from animals to humans is mainly through consumption andhandling of animal food products but also direct contact with colonised ...
Jacobs-Reitsma, W.F. +2 more
openaire +4 more sources
An improved culture method for selective isolation of Campylobacter jejuni from wastewater
Campylobacter jejuni is one of the leading foodborne pathogens worldwide. C. jejuni is isolated from a wide range of foods, domestic animals, wildlife, and environmental sources.
Jinyong Kim +12 more
doaj +1 more source
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury +3 more
wiley +1 more source
Geographic determinants of reported human Campylobacter infections in Scotland [PDF]
<p><b>Background:</b> Campylobacteriosis is the leading cause of bacterial gastroenteritis in most developed countries. People are exposed to infection from contaminated food and environmental sources.
Strachan, N.J. +44 more
core +1 more source
Background Campylobacter jejuni is the leading cause of bacterial gastroenteritis (campylobacteriosis) in humans worldwide, and the most frequent pathogen associated with Guillain-Barré syndrome (GBS) and Miller-Fisher syndrome (MFS).
Krzysztof Fiedoruk +5 more
doaj +1 more source
Detection of Antibiotic‐Resistant Campylobacter on Retail Chicken in New Zealand: A Sentinel Survey
Antibiotics are relied upon to treat and prevent infections in humans, animals, and plants. However, antimicrobial use, particularly when unnecessary or inappropriate, has contributed to the emergence and dissemination of antimicrobial resistance (AMR).
Kathleen J. Sircombe +2 more
wiley +1 more source
Temporal and farm-management-associated variation in the faecal-pat prevalence of Campylobacter jejuni in ruminants [PDF]
In a 2-year longitudinal study of adult animals on 15 dairy farms and four sheep farms in Lancashire, UK. C. jejuni was isolated from all farms, although not on every occasion.
French, N. P. +4 more
core
Development of two alternative models of campylobacter jejuni infection that more closely mimic the in vivo environment [PDF]
Campylobacter JeJum IS the leading cause of foodborne gastroenteritis worldwide, yet despite the organism's prevalence, relatively little is known about the mechanisms of pathogenesis.
Mills, Dominic Christopher
core +1 more source

