Results 101 to 110 of about 14,945 (175)

Safety and effectiveness of the combination of 5‐azacitidine and ruxolitinib in VEXAS syndrome: A single‐centre experience

British Journal of Haematology, EarlyView.
Gregorio Maria Bergonzi, Enrico Cozzo, Alessandro Tomelleri, Costanza Piccolo, Gianluca Scorpio, Carmelo Gurnari, Francesca Romano, Marco Matucci‐Cerinic, Lorenzo Dagna, Massimo Bernardi, Luca Vago, Fabio Ciceri, Corrado Campochiaro, Elisa Diral   +13 more
wiley   +1 more source

Metabolic and Crystal Arthropathies [70-72]: 70. Single Intramuscular Depot Methylprednisolone Injection: A Convenient, Efficacious and Safe Treatment for Gouty Arthritis in an Inpatient Setting [PDF]

, 2017
Background: Various modalities of treatment have been used and recommended in the treatment of acute gout. These include drugs such as colchicine, NSAIDs and oral prednisolone.
Arulmani, Udayasankar, Bodalia, Bhavesh, Dasgupta, Bhaskar, Gendi, Nagui, Hassan, Nada, Hassan, Nada, Ishorari, Jasmine, Meulemeester, Marc D., Murphy, Valda, Pikhlak, Andrey, Richard, Dominik, Sallstig, Peter, Schlesinger, Naomi, Shamim, Talha, So, Alexander, Yücel, A. Eftal   +15 more
core  

Experience of the successful treatment with canakinumab of a patient with NLPC4-associated autoinflammatory syndrome with enterocolitis

Педиатрическая фармакология, 2016
The article shows the observation of rare NLPC4-associated autoinflammatory syndrome with enterocolitis and familial cold urticaria. Diagnosis is confirmed molecularly-genetically: previously not described mutation c.928C>T in the heterozygous state ...
T. V. Sleptsova, E. I. Alexeeva, K. V. Savost’yanov, A. A. Pushkov, T. M. Bzarova, S. I. Valieva, O. L. Lomakina, R. V. Denisova, K. B. Isaeva, E. G. Chistyakova   +9 more
doaj   +1 more source

Anakinra and related drugs targeting interleukin-1 in the treatment of cryopyrin-associated periodic syndromes [PDF]

, 2014
Anakinra is an interleukin (IL) receptor antagonist that works by blocking the biological activity of IL-1 by competitively inhibiting binding of IL-1 to the type 1 interleukin receptor.
Bachove, Inessa, Chang, Christopher
core   +2 more sources

IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone? [PDF]

, 2016
Although in the past the prevention of joint destruction in rheumatoid arthritis (RA) was strongly emphasized, now a great interest is focused on associated comorbidities in these patients. Multiple data suggest that a large percentage of RA patients are
Alvaro, S., Berardicurti, O., Carubbi, F., CICCIA, Francesco, Cipriani, P., Di Benedetto, P., Giacomelli, R., GUGGINO, Giuliana, Liakouli, V., Ruscitti, P., TRIOLO, Giovanni   +10 more
core   +1 more source

Efficacy and safety of canakinumab in systemic juvenile idiopathic arthritis, the first Chinese experience

Pediatric Rheumatology Online Journal
Background Systemic juvenile idiopathic arthritis (sJIA) is a severe form of juvenile arthritis that is characterized by chronic joint inflammation and systemic symptoms such as fever, rash, and organ involvement.
Lingzhi Qiu, Le Ma, Yifan Xie, Jing Jin, Yuting Pan, Shumin Li, Zhidan Fan, Haiguo Yu   +7 more
doaj   +1 more source

EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME

Вопросы современной педиатрии, 2016
The article presents a case of a successful canakinumab application (preparation of monoclonal antibodies to 1 interleukin) for undifferentiated autoinflammatory syndrome in a patient with refractoriness to oral glucocorticosteroids and genetically ...
Tatyana V. Sleptsova, Еkaterina I. Alexeeva, Тatyana М. Bzarova, Kirill V. Savostyanov, Аlexander A. Pushkov, Kseniya B. Isaeva, Rina V. Denisova, Оlga L. Lomakina   +7 more
doaj   +1 more source

Microcrystals as DAMPs and their role in joint inflammation [PDF]

, 2017
Microcrystals associated with joint diseases, namely monosodium urate, calcium pyrophosphate and basic calcium phosphate, can be considered as ‘danger signals' to the innate immune system and provoke inflammation through inflammasome-dependent as well as
Busso, Nathalie, So, Alexander
core  

Severe Inflammation Following Vaccination Against Streptococcus pneumoniae in Patients With Cryopyrin-Associated Periodic Syndromes [PDF]

, 2016
OBJECTIVE: Pneumococcal vaccination is recommended for patients receiving immunosuppressive drugs. We describe unusually severe adverse reactions to pneumococcal vaccination in each of 7 consecutive patients with cryopyrin-associated periodic ...
Hawkins, PN, Hoffman, HM, Kuemmerle-Deschner, J, Walker, UA, Williams, R   +4 more
core  

Treatment of systemic-onset juvenile arthritis with canakinumab

Open Access Rheumatology: Research and Reviews, 2015
Joachim Peitz, Gerd Horneff Pediatric Rheumatology Centre, Department of General Pediatrics and Neonatology, Asklepios Clinic, Sankt Augustin, Germany Abstract: Treatment of systemic-onset juvenile idiopathic arthritis is challenging, but the ...
Peitz J, Horneff G
doaj