Results 191 to 200 of about 11,333,085 (312)

Editorial: Role of fibroblast in cancer

Frontiers in Molecular Biosciences
Xuezhen Zeng, Man Liu
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Role of Cancer Associated Fibroblast (CAF) derived miRNAs on head and neck malignancies microenvironment : a systematic review

Role of Cancer Associated Fibroblast (CAF) derived miRNAs on head and neck malignancies microenvironment : a systematic ...
Mansour Gorjizad, Samaneh Zand, hesam mobaraki, Parsa Golestannejad, Farahnaz Zhian Zargaran, sara hemmati, Pouya Asgari, Ali Akbar Senobari Ghezeljemeidan, Mahsa Asadi Anar, mohammad khosravani, mohamad parsa monkaresi, parsa ghasemi   +11 more
core   +1 more source

Identification of cancer-associated fibroblast biomarkers in cutaneous squamous cell carcinoma. [PDF]

Oncol Lett
Deng Y, Qi J, Tang Y, Cun Y, He Q, He L.
europepmc   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Dissecting FAP+ Cell Diversity in Pancreatic Cancer Uncovers an Interferon-Response Subtype of Cancer-Associated Fibroblasts with Tumor-Restraining Properties

Within the stroma of pancreatic ductal adenocarcinoma (PDAC), mesenchymal cells differentiate into cancer-associated fibroblast (CAF) subtypes that differentially mediate disease progression.
Pietras, Kristian, Dehghan-Nayeri, Mohammad Javad, Cumming, Joshua, Öhlund, Daniel, Patthey, Cedric, Dongre, Mitesh, Alsaed, Tala, Ling, Agnes, Maneshi, Parniyan, Cumming, Joshua,, Ling, Agnes,, Maneshi, Parniyan,, Alsaed, Tala,, Pietras, Kristian,, Dongre, Mitesh,, Patthey, Cedric,, Öhlund, Daniel,, Dehghan-Nayeri, Mohammad Javad,, Lund University.   +18 more
core   +1 more source

Translational Insights into Cancer-Associated Fibroblast Infiltration-Related Biomarkers in Glioblastoma and Their Clinical Prognostic Value

International Journal of General Medicine
Yuxuan Zhang, Qibing Huang Department of Emergency Neurosurgical Intensive Care Unit, Qilu Hospital of Shandong University, Jinan, 250012, People’s Republic of ChinaCorrespondence: Qibing Huang, Department of Emergency Neurosurgical Intensive Care Unit ...
Zhang Y, Huang Q
doaj  

The Role of Distinct Cancer-Associated Fibroblast Subtypes in Prostate Cancer Immunotherapy. [PDF]

Int J Biol Sci
He K, Zhao Z, Bai J, Lu T, Hu Y, He X, Wei F, Zhang Y, Gu Y, Shi Z, Meng X, Wang F, Shi C, Qin W, Zhang K, Xie Q, Yang L.   +16 more
europepmc   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

BRAF Inhibition-Associated Nuclear Remodeling is Linked to Cancer-Associated Fibroblast Activation. [PDF]

Cancer Res Commun
Wang J, Soley BDS, Xiao Y, Siegfried LG, Zhou L, Xu M, Millar S, Andl T, Zhang Y.   +8 more
europepmc   +1 more source