Results 41 to 50 of about 3,021,316 (188)

Design and synthesis of coumarin-based organoselenium as a new hit for myeloprotection and synergistic therapeutic efficacy in adjuvant therapy

Scientific Reports, 2018
A newly designed organoselenium compound, methyl substituted umbelliferone selenocyanate (MUS), was synthesized as a primary hit against the myelotoxic activity of carboplatin. MUS was administered at 6 mg/kg b.wt, p.o.
Arup Ranjan Patra, Somnath Singha Roy, Abhishek Basu, Avishek Bhuniya, Arin Bhattacharjee, Subhadip Hajra, Ugir Hossain Sk, Rathindranath Baral, Sudin Bhattacharya   +8 more
doaj   +1 more source

Preventative therapies for healthy women at high risk of breast cancer [PDF]

, 2014
Ivana Sestak Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London, UKAbstract: Tamoxifen has been shown to reduce the risk of developing estrogen receptor (ER)-positive ...
Sestak I, Sestak, I
core   +1 more source

Ethanolic Extract of Citrus reticulata Peel Inhibits the Migration of WiDr Colon Cancer Cells [PDF]

, 2020
Colorectal cancer is third rank on the cancer cases in Indonesia. To cure the cancer needs big cost and lot of effort. On the other side, the side effect of medicine or chemotherapy on patient need to reduce.
Astuti, Yoni, Primasari, Aulia
core   +1 more source

Pentagamaboronon-0-Sorbitol Induces Apoptosis through Elevation of Reactive Oxygen Species in Triple Negative Breast Cancer Cells [PDF]

, 2021
Breast cancer is the most common type of cancer causing mortality for women due to metastasis. More than 50% of breast cancer patients are suffered lung metastases.
Hermawan, Adam, Utomo, Rohmad Yudi, Ramadani, Ratna Dwi, Meiyanto, Edy   +3 more
core   +1 more source

Breast cancer chemoprevention : economic and policy considerations. [PDF]

The potential for chemoprevention of breast cancer depends on the benefits being achieved at reasonable cost. This study assesses the economics of chemoprevention of breast cancer with tamoxifen within the context of the ...
Frater, Alison
core   +1 more source

Intermittent Chemoprevention of Colon Cancer

, 2015
This video shows the advantage of intermittent pulse schedules compared to constant schedules, for the chemoprevention of colon cancer in a computer simulation of cell dynamics in human colon crypts.Supplemental data for a manuscript prepared for ...
Axelrod, David E.
core   +1 more source

Natural flavonoid Orientin restricts 5-Fluorouracil induced cancer stem cells mediated angiogenesis by regulating HIF1α and VEGFA in colorectal cancer

Molecular Medicine
Background Cancer stem cells are a small subpopulation of cells which are responsible for tumor metastasis, angiogenesis, drug resistance etc. 5-Fluorouracil (5FU), a common therapeutic drug used in colorectal cancer treatment is reported to enrich CSCs,
Rituparna Ghosh, Arijit Bhowmik, Souradeep Biswas, Priya Samanta, Rupali Sarkar, Shampa Pakhira, Mrinmoyee Mondal, Subhadip Hajra, Prosenjit Saha   +8 more
doaj   +1 more source

The Chemopreventive Activity of Indonesia Medicinal Plants Targeting on Hallmarks of Cancer [PDF]

Advanced Pharmaceutical Bulletin, 2019
Cancer remains a complex disease with increasing global mortality and morbidity. Numerous theories have been established to understand the biological mechanism underlying cancer.
Edy Meiyanto, Yonika Arum Larasati
doaj   +1 more source

Selectivity Index of Alpinia galanga Extract and 1’-Acetoxychavicol Acetate on Cancer Cell Lines [PDF]

, 2019
Previous research stated that galangal (Alpinia galanga) extract has a potential as cytotoxic agent with active compound of 1’-Acetoxychavicol Acetate (ACA).
Haryanti, Sari, Meilinasary, Khairunnisa Azani, Da'i, Muhammad, Suhendi, Andi   +3 more
core   +1 more source

Exosome-sheathed porous silica nanoparticle-mediated co-delivery of 3,3′-diindolylmethane and doxorubicin attenuates cancer stem cell-driven EMT in triple negative breast cancer

Journal of Nanobiotechnology
Background Therapeutic management of locally advanced and metastatic triple negative breast cancer (TNBC) is often limited due to resistance to conventional chemotherapy.
Rupali Sarkar, Souradeep Biswas, Rituparna Ghosh, Priya Samanta, Shampa Pakhira, Mrinmoyee Mondal, Yashaswi Dutta Gupta, Suman Bhandary, Prosenjit Saha, Arijit Bhowmik, Subhadip Hajra   +10 more
doaj   +1 more source