Results 31 to 40 of about 2,928,478 (311)

Quality management in radiation therapy: A 15 year review of incident reporting in two integrated cancer centres

open access: yesTechnical Innovations & Patient Support in Radiation Oncology, 2020
Fifteen years of reported incidents were reviewed to provide insight into the effectiveness of an Incident Learning System (ISL). The actual error rate over the 15 years was 1.3 reported errors per 1000 treatment attendances.
Sandie Smith   +8 more
doaj   +1 more source

Non-chemotherapy adjuvant agents in TP53 mutant Ewing sarcoma

open access: yesScientific Reports, 2023
Ewing sarcoma (EWS) is a malignant tumor arising in bone or soft tissue that occurs in adolescent and young adult patients as well as adults later in life.
Jin-Ah Kim   +11 more
doaj   +1 more source

Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer. [PDF]

open access: yes, 2014
Preventing breast cancer is an effective strategy for reducing breast cancer deaths. The purpose of chemoprevention (also termed preventive therapy) is to reduce cancer incidence by use of natural, synthetic, or biological agents.
Brown, Powel H, Litzenburger, Beate C
core   +1 more source

Role of ultraviolet mutational signature versus tumor mutation burden in predicting response to immunotherapy

open access: yesMolecular Oncology, 2020
Hydrophobic neoantigens are more immunogenic because they are better presented by the major histocompatibility complex and better recognized by T cells. Tumor cells can evade the immune response by expressing checkpoints such as programmed death ligand 1.
Timothy V. Pham   +6 more
doaj   +1 more source

Oral ethinylestradiol in castration resistent prostate cancer: 10 year experience [PDF]

open access: yes, 2015
To describe our 10-year experience with the use of oral ethinylestradiol in the treatment of metastatic castration-resistant prostate cancer. METHODS: From February 2000 to April 2010, 116 patients with a metastatic castration-resistant prostate cancer
Aggarwal   +16 more
core   +1 more source

Cancer Pain and Therapy

open access: yesActa Clinica Croatica, 2022
Cancer pain is not a homogenous and clearly understood pathological process. The best treatment is a combination of drug and non-drug measures. Pain is divided into visceral, bone or neuropathic pain and has characteristics of continuous or intermittent pain.
Brozović, Gordana   +4 more
openaire   +4 more sources

Hedgehog Signalling in Androgen Independent Prostate Cancer [PDF]

open access: yes, 2008
Objectives: Androgen-deprivation therapy effectively shrinks hormone-naïve prostate cancer, both in the prostate and at sites of distant metastasis.
Bisson, Isabelle   +7 more
core   +1 more source

A TCR-based Chimeric Antigen Receptor

open access: yesScientific Reports, 2017
Effector T cells equipped with engineered antigen receptors specific for cancer targets have proven to be very efficient. Two methods have emerged: the Chimeric Antigen Receptors (CARs) and T-cell Receptor (TCR) redirection.
Even Walseng   +8 more
doaj   +1 more source

Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer [PDF]

open access: yes, 2019
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, incurable cancer with a 20% 1 year survival rate. While standard-of-care therapy can prolong life in a small fraction of cases, PDAC is inherently resistant to current treatments, and novel ...
Adile, Ashley A.   +19 more
core   +3 more sources

Enhanced anticancer activity of a combination of docetaxel and Aneustat (OMN54) in a patient-derived, advanced prostate cancer tissue xenograft model. [PDF]

open access: yes, 2013
The current first-line treatment for advanced metastatic prostate cancer, i.e. docetaxel-based therapy, is only marginally effective. The aim of the present study was to determine whether such therapy can be improved by combining docetaxel with Aneustat (
Collins, Colin C   +9 more
core   +1 more source

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