Results 31 to 40 of about 17,554 (214)

Candesartan modulates microglia activation and polarization via NF-κB signaling pathway

International Journal of Immunopathology and Pharmacology, 2020
Microglia are diverse cells that acquire different functional phenotypes in response to microenvironment in which they reside. Several transcriptional regulators have been identified that regulate different microglia phenotypes.
Shuyan Qie, Yuanyuan Ran, Xiaosheng Lu, W. Su, Wei Li, J. Xi, Weijun Gong, Zongjian Liu   +7 more
semanticscholar   +1 more source

Candesartan Cilexetil In Vitro–In Vivo Correlation: Predictive Dissolution as a Development Tool

Pharmaceutics, 2020
The main objective of this investigation was to develop an in vitro–in vivo correlation (IVIVC) for immediate release candesartan cilexetil formulations by designing an in vitro dissolution test to be used as development tool.
Andrés Figueroa-Campos, Bárbara Sánchez-Dengra, V. Merino, A. Dahan, I. González-Álvarez, A. García‐Arieta, M. González-Álvarez, M. Bermejo   +7 more
semanticscholar   +1 more source

CANDESARTAN COULD AMELIORATE THE COVID-19 CYTOKINE STORM

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020
Background. Angiotensin receptor blockers (ARBs) reducing inflammation and protecting lung and brain function, could be of therapeutic efficacy in COVID-19 patients. Methods.
Abdel G. Elkahloun, J. M. Saavedra
semanticscholar   +1 more source

Sartans in hypertension treatment: advantages of candesartan use

, 2019
Aim. To present a scientific review of angiotensin II (AT II) receptor blockers (sartans) clinical pharmacology, in particular pharmacologic and clinical characteristics of candesartan. Materials and methods.
Marina V. Leonova
core   +1 more source

CHARMed - the effects of candesartan in heart failure

, 2005
The Candesartan in Heart failure: Assessment of Reduction in Mortality and mortality (CHARM) programme has already shown that candesartan is an effective alternative to angiotensin-converting enzyme (ACE) inhibitors (CHARM-Alternative), that additional ...
Doggrell, Sheila A., Doggrell, Sheila
core   +1 more source

Antihypertensive efficacy and tolerability of candesartan-hydrochlorothiazide 32/12.5 mg and 32/25 mg in patients not optimally controlled with candesartan monotherapy

, 2008
Aim. To evaluate the efficacy and tolerability of candesartan cilexetil 32 mg in combination with hydrochlorothiazide (HCT) 12.5 mg or 25 mg in hypertensive patients not optimally controlled with candesartan monotherapy. Patients and methods.
Locatelli, F., Cabrera, W., Maus, O., Petrov, A., Yspenskiy, Y., Espinoza, J., Salomone, O., Jourde, P., Luquez, H., Daut, W., Rojas, C., Glorioso, N., Rodenas, P., Bustamante, G., Bönner, Gerd, Saint-Lannes, M., Puig, J., Balparda, C., Montaña, O., Horna, M., Aizenberg, D., Krause, G., Guerin, P., Churina, S., Parra, J., Muenter, K. C., Heredia, J., Comino, L., Naumburger, A., Santonastaso, M., Sechi, L., Mengual, L., Di Biase, M., Licata, G., Perticone, M., Radermacher, E., Cama, R., Aucello, G., Lecocq, L., Cantin, T., Donadon, V., Sipan, Y., Fiesselmann, A., Ershova, O., Destro, M., Vinyoles, E., Vidyasagar, S., Jure, H., Shoustov, S., Svistov, A., Bosi, S., Di Somma, S., Mayer, M., Rossi, P., Butko, D., Konrady, A., Aim, L., Bertrand, G., Strotmann, H. -J., Cuneo, C., Frohn, M., Calabuig, J., Mos, L., Richter, D., Toce, L., Chevts, J., Volpe, M., Fluixa, C., Pedrinelli, R., Mezzetti, A., Pau, J., Lalanne, G., Hanefeld, M., Thomas, M., Uguccioni, M., Espinel-Garuz, E., Perez, J., Leyendecker, P., Karnad, D., Vinciguerra, A., Combet, G., Andreas, K., Smila, D., Gazzaruso, C., Watanabe, L., Bryce, A., Dammann, H. -G., Kostenko, V.   +87 more
core   +2 more sources

Analisis Efektivitas Biaya Pengobatan Kombinasi Candesartan-Amlodipin Dibandingkan dengan Kombinasi Candesartan-Diltiazem pada Pasien Hipertensi Rawat Jalan [PDF]

, 2017
Pengobatan hipertensi membutuhkan biaya yang besar, karena dilakukan dalam jangka waktu yang panjang. Adanya efektivitas antihipertensi yang berbeda-beda maka perlu dilakukan penelitian yang bertujuan untuk mengetahui efektivitas biaya pengobatan ...
Baroroh, F. (Faridah), Andriana Sari, Sari, A. (Andriana), Faridah Baroroh   +3 more
core   +1 more source

Cost Effectiveness Analysis of Candesartan Therapy in Comparison to Candesartan-Amlodipine Therapy on Hypertensive Outpatients

, 2019
BACKGROUND: he achievement of optimal hypertension therapy requires cost-effective medicine. The treatment of hypertensive patients needs for long-term medication have made medical costs a prime issue in health economics.
Baroroh, Faridah, Masruroh, Noviana, Sari, Andriana   +2 more
core   +1 more source

COST-EFFECTIVENESS ANALYSIS (CEA) OBAT ANTIHIPERTENSI CANDESARTAN DIBANDINGKAN DENGAN KOMBINASI CANDESARTAN-BISOPROLOL PADA PASIEN HIPERTENSI RAWAT JALAN DI RSIJ CEMPAKA PUTIH [PDF]

, 2020
Hipertensi didefinisikan sebagai tekanan darah arteri yang meningkat secara persisten. Prevalensi hipertensi di daerah Jakarta yaitu sebesar ≥ 30%. Oleh karena itu, perlu dilakukan Cost-Effectiveness Analysis untuk memperoleh terapi obat yang paling ...
Aryadi, Ika Chintia Maryam, Wiyati, Tuti, Syaripuddin, Muhamad   +2 more
core  

Effectiveness of galcanezumab versus topiramate, amitriptyline, and other select traditional oral migraine preventives with evidence of efficacy: 3‐Month results from the TRIUMPH study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To compare the 3‐month effectiveness of galcanezumab with select traditional oral migraine preventive (TOMP) medications recommended by scientific societies (TOMP efficacy subset) and with the most frequently used individual TOMP medications.
Shivang Joshi, Cristina Tassorelli, Manjit Matharu, Taoufik Alsaadi, Carlos Vallarino, Lars Viktrup, Maurice Vincent, Rebecca L. Robinson   +7 more
wiley   +1 more source