Results 71 to 80 of about 224,806 (322)

A Pilot Study Showing Fluconazole and Flucytosine Activities against Candida glabrata are Affected by Low pH: Implications for the Treatment of Recurrent Vulvovaginal Candidiasis

Clinical and Experimental Obstetrics & Gynecology
Background: Candida albicans (C. albicans) and Candida glabrata (C. glabrata) are mainly associated with vulvovaginal candidiasis (VVC). Management of VVC caused by C.
Ziauddin Khan, Suhail Ahmad, Mohammad Asadzadeh   +2 more
doaj   +1 more source

Candida and Porphyromonas gingivalis: the effect on wound closure in vitro

Journal of Oral Microbiology, 2017
Microorganisms play a role in oral mucositis after cancer therapy. The current study explored the hypothesis that Candida spp. alone and together with Porphyromonas gingivalis cause delayed healing of oral ulcerations due to the inhibition of wound ...
Thijs M. Haverman, Alexa M. G. A. Laheij, Johannes J. de Soet, Jan de Lange, Frederik R. Rozema   +4 more
doaj   +1 more source

Lactate signalling regulates fungal β-glucan masking and immune evasion [PDF]

, 2016
AJPB: This work was supported by the European Research Council (STRIFE, ERC- 2009-AdG-249793), The UK Medical Research Council (MR/M026663/1), the UK Biotechnology and Biological Research Council (BB/K017365/1), the Wellcome Trust (080088; 097377).
A Hopke, B Ferwerda, BN Gantner, C Kuei, CA Johnston, CA Munro, CA Rappleye, CJ Barelle, CJ Heilmann, DH Owen, DO Inglis, E Leberer, FN Gravelat, G Bindea, GD Brown, GJ Sosinska, HJ Flint, I Jacobs, ID Iliev, IV Ene, IV Ene, IV Ene, IV Ene, JE Nett, JM Bain, K Lemaire, LE Lewis, LM Graham, M Galán-Díez, M Karababa, M Santos, MG Netea, MG Netea, MJ Marakalala, MM Maidan, MT Kelly, N Vieira, NAR Gow, P Shannon, PR Desai, RA Hall, RT Wheeler, RT Wheeler, RT Wheeler, S Lev, S Shahana, SdJ Carrion, SE Hardison, SM Noble, TR O'Meara, YL Chen   +50 more
core   +1 more source

Low Level of Antifungal Resistance in Iranian Isolates of Candida glabrata Recovered from Blood Samples in a Multicenter Study from 2015 to 2018 and Potential Prognostic Values of Genotyping and Sequencing of PDR1

Antimicrobial Agents and Chemotherapy, 2019
Establishing an effective empirical antifungal therapy requires that national surveillance studies be conducted. Herein, we report the clinical outcome of infections with and the microbiological features of Iranian isolates of Candida glabrata derived ...
A. Arastehfar, F. Daneshnia, K. Zomorodian, M. Najafzadeh, S. Khodavaisy, H. Zarrinfar, F. Hagen, Zahra Zare shahrabadi, M. Lackner, H. Mirhendi, M. Salehi, M. Roudbary, W. Pan, M. Kostrzewa, T. Boekhout   +14 more
semanticscholar   +1 more source

The Application Value of Bronchoalveolar Lavage Fluid Metagenomic Next‐Generation Sequencing in Moderate‐to‐Severe Bronchiectasis

Journal of Clinical Laboratory Analysis, EarlyView.
This study analyzed the clinical data of 52 patients with moderate‐to‐severe bronchiectasis who were admitted to our hospital. It explored the diagnostic value of bronchoalveolar lavage fluid (BALF) metagenomic next‐generation sequencing (mNGS) in identifying infectious pathogens in patients with moderate‐to‐severe bronchiectasis, and clarified the ...
Jiachun Li, Qiuping Quan, Junshan Chen, Xiaoyun Jian, Weijie Zhan, Jingmin Wang, Rongbin Jiang   +6 more
wiley   +1 more source

Differential Virulence of Candida glabrata Glycosylation Mutants [PDF]

Journal of Biological Chemistry, 2013
The fungus Candida glabrata is an important and increasingly common pathogen of humans, particularly in immunocompromised hosts. Despite this, little is known about the attributes that allow this organism to cause disease or its interaction with the host immune system. However, in common with other fungi, the cell wall of C.
West, L., Lowman, D.W., Mora-Montes, H.M., Grubb, S., Murdoch, C., Thornhill, M.H., Gow, N.A.R., Williams, D., Haynes, K.   +8 more
openaire   +4 more sources

Phosphate in Virulence of Candida albicans and Candida glabrata [PDF]

Journal of Fungi, 2020
Candida species are the most commonly isolated invasive human fungal pathogens. A role for phosphate acquisition in their growth, resistance against host immune cells, and tolerance of important antifungal medications is becoming apparent. Phosphorus is an essential element in vital components of the cell, including chromosomes and ribosomes. Producing
Julia R. Köhler, Maikel Acosta-Zaldívar, Wanjun Qi   +2 more
openaire   +3 more sources

Synergistic Interactions between Pseudomonas aeruginosa and Candida albicans, Candida glabrata, Candida krusei, Candida parapsilosis as well as Candida tropicalis in the Formation of Polymicrobial Biofilms

Journal of Pure and Applied Microbiology
The interactions between pathogens during infection and the impact of these interactions on drug effectiveness are poorly understood, making polymicrobial infections challenging to treat. During an infection, cross-interactions between bacteria and fungi
Yenni Andriana, Agung Dwi Wahyu Widodo, Muhammad Vitanata Arfijanto   +2 more
doaj   +1 more source

Set of Classical PCRs for Detection of Mutations in Candida glabrata FKS Genes Linked with Echinocandin Resistance [PDF]

, 2014
Clinical echinocandin resistance among Candida glabrata strains is increasing, especially in the United States. Antifungal susceptibility testing is considered mandatory to guide therapeutic decisions.
Afeltra, Javier, Dudiuk, Catiana Beatriz, Gamarra, Maria Soledad, Garcia, Guillermo Manuel, Jimenez Ortigoza, Cristina, Leonardelli, Florencia, Perlin, David S., Vitale, Roxana Gabriela   +7 more
core   +2 more sources

Synovial interleukin‐6 point‐of‐care testing, alone and combined with D‐dimer, supports rapid diagnosis of periprosthetic joint infection

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Data on the reliability of point‐of‐care (POC) tests for the rapid diagnosis of periprosthetic joint infections (PJI) using synovial fluid (SF) D‐dimer (DD), interleukin 6 (IL‐6) and procalcitonin (PCT) are limited. This study aimed to address this issue by evaluating the diagnostic accuracy of POC tests for SF DD, IL‐6 and PCT in ...
Sujeesh Sebastian, Hibah Abdulwahab Abusulaiman, Veronika Achatz, Matteo Spadini, Tobias Josef Niedrist, Markus Herrmann, Jochen Gerhard Hofstaetter   +6 more
wiley   +1 more source