Results 101 to 110 of about 1,663 (175)
“Nutrient–fungi–host” tripartite interaction in cancer progression
iMeta, Volume 3, Issue 2, April 2024.Interactions between nutrient and fungi in cancer development and treatment remain under investigation. In this article, we aim to provide insights into the relationships between fungi and various categories of cancer, mediated by diverse nutrient sensing pathways of fungi in response to external environment.
Di Wu +6 more
wiley +1 more source
Oral epithelial IL-22/STAT3 signaling licenses IL-17-mediated immunity to oral mucosal candidiasis [PDF]
, 2020 Oropharyngeal candidiasis (OPC; thrush) is an opportunistic infection caused by the commensal fungus Candida albicans Interleukin-17 (IL-17) and IL-22 are cytokines produced by type 17 lymphocytes.
Aggor, Felix E.Y. +16 more
core +2 more sources
Characterization and evaluation of the antifungal activity of antibodies raised against Candida Albicans germ tube in a rabbit model of infection and patients with invasive Candidiasis. [PDF]
, 2018 236 p.In the last decades, the incidence of Invasive Candidiasis has dramatically increased. Since Candida is a common component of human microbiota, the distinction between invasion and colonization is complicated.
Carrano, Giulia
core +4 more sources
Diverse mechanisms control amino acid‐dependent environmental alkalization by Candida albicans
Molecular Microbiology, Volume 121, Issue 4, Page 696-716, April 2024.Glutamate dehydrogenase (Gdh2), a central enzyme of nitrogen metabolism, is dispensable for the virulent growth of Candida spp., including C. albicans, C. glabrata, and C. auris. Gdh2 deaminates mitochondria‐derived glutamate generating ammonia, alkalinizing the extracellular environment.
Fitz Gerald S. Silao +4 more
wiley +1 more source
Molecular Microbiology, Volume 121, Issue 4, Page 727-741, April 2024.The regulatory factor X (RFX) gene family comprises a diverse group of transcriptional regulators with a unique winged‐helix DNA binding domain. In contrast to model yeasts that harbor a single RFX gene, the genome of the pathogenic yeast C. albicans encodes two RFX homologs.
Diana L. Rodríguez +2 more
wiley +1 more source
European Journal of Immunology, Volume 54, Issue 3, March 2024.Abstract Candida albicans causes opportunistic infections ranging from mucosal mycoses to life‐threatening systemic infections in immunocompromised patients. During C. albicans infection, leukotrienes and prostaglandins are formed from arachidonic acid by 5‐lipoxygenase (5‐LOX) and cyclooxygenases, respectively to amplify inflammatory conditions, but ...
Jana Schimanski +5 more
wiley +1 more source
Recruitment of both the ESCRT and autophagic machineries to ejecting Mycobacterium marinum
Molecular Microbiology, Volume 121, Issue 3, Page 385-393, March 2024.Cytosolic Mycobacterium marinum exits the amoeba Dictyostelium discoideum through the ejectosome structure in a non‐lytic fashion. Here, we show that both, the ESCRT‐ and autophagic‐machinery are recruited to ejecting bacteria and their localization partially depends on each other. We hypothesize that a frustrated autophagosome engulfs the bacterium on
Lilli Gerstenmaier +5 more
wiley +1 more source
PLoS PathogensThe opportunistic fungal pathogen Candida albicans thrives on human mucosal surfaces as a harmless commensal, but frequently causes infections under certain predisposing conditions.
Jakob L Sprague +13 more
doaj +1 more source
EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin [PDF]
, 2022 Nicole O. Ponde +9 more
openalex +1 more source