Results 101 to 110 of about 1,118 (147)

Quantification of biophysical properties of candidalysin, a fungal peptide toxin secreted by C. albicans during invasion [PDF]

, 2023
Gaukhar Zhurgenbayeva, Christian Eggeling   +1 more
openalex   +1 more source

Candida albicans epithelial invasion induces host membrane rupture at distinct subcellular niches following priming by the fungal toxin candidalysin [PDF]

Noa Conan, Laura Marthe, Anouck Shekoory, Patricia Latour‐Lambert, Jean‐François Franetich, Martin Larsen, Allon Weiner   +6 more
openalex   +1 more source

Decision letter: The Candida albicans virulence factor candidalysin polymerizes in solution to form membrane pores and damage epithelial cells

, 2022
Ioan Iacovache
openalex   +1 more source

Identification of Candidalysin: a Candida albicans peptide toxin involved in epithelial damage [PDF]

, 2016
Sarah Höfs
openalex  

Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin [PDF]

, 2017
Akash Verma, Jonathan P. Richardson, Chunsheng Zhou, Bianca M. Coleman, David L. Moyes, Jemima Ho, Anna R. Huppler, Kritika Ramani, Mandy J. McGeachy, Ilgiz A. Mufazalov, Ari Waisman, Larry Kane, Partha S. Biswas, Bernhard Hube, Julian R. Naglik, Sarah L. Gaffen   +15 more
openalex   +1 more source

A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis via altered secretion of candidalysin

, 2021
Junyan Liu, Emily A. Sansevere, Katherine S. Barker, Hubertine M. E. Willems, David J. Lowes, Brian M. Peters   +5 more
openalex   +1 more source

Pectins Mitigate Gut Barrier Disruption and Inflammation Induced by Candida Albicans-Derived Toxin Candidalysin in Vitro in a Degree of Methyl-Esterification Manner

Naschla Gasaly, Xiaochen Chen, Luis Silva, Isaura Beatriz Borges Silva, Marcela A. Hermoso, Paul de Vos   +5 more
openalex   +1 more source

Fungal infection drives metabolic reprogramming in epithelial cells via aerobic glycolysis and an alternative TCA cycle shunt. [PDF]

Sci Adv
Pellon A, Sadeghi Nasab SD, Bidkhori G, Griffiths JS, Vaga S, Begum N, Blagojevic M, Sigh NK, Kotowicz NK, Uzochukwu I, Le Guennec A, Henley-Smith R, Gregson-Williams H, Clasen F, Pryce M, Karimpour N, Cook R, Anguita J, Richardson JP, Thavaraj S, Naglik JR, Shoaie S, Moyes DL.   +22 more
europepmc   +1 more source

Critical parameters of fungal pathogenicity at the epithelial interphase. [PDF]

Microlife
Möslinger A, Allert S, Vylkova S, Hube B.   +3 more
europepmc   +1 more source

雌激素和Candidalysin在外阴阴道念珠菌病中的研究进展

Zhongshan Daxue xuebao. Yixue kexue ban
外阴阴道念珠菌病（VVC）主要由白念珠菌（CA）引起。增加外周血雌激素水平如怀孕、口服避孕药的使用和激素替代疗法等增加VVC易感性。雌激素可通过调控CA菌丝生长、宿主固有免疫细胞和阴道上皮细胞的免疫功能等多种方式影响VVC进展，但具体机制仍不清楚。Candidalysin（CL）是一种对黏膜感染至关重要的真菌肽毒素，在CA感染中起着重要作用。CL由ECE1基因编码，雌激素调控ECE1表达。本文就雌激素和CL与 VVC之间相关性进行综述，为进一步明确雌激素和CL在VVC发病机制中的作用提供参考。
夏婷婷, 黄怀球
doaj