Results 101 to 110 of about 635 (146)

Global Transcriptomic Analysis of the Candida albicans Response to Treatment with a Novel Inhibitor of Filamentation

mSphere, 2019
The opportunistic pathogenic fungus Candida albicans can cause devastating infections in immunocompromised patients. Its ability to undergo a morphogenetic transition from yeast to filamentous forms allows it to penetrate tissues and damage tissues, and ...
Jesus A. Romo, Hao Zhang, Hong Cai, David Kadosh, Julia R. Koehler, Stephen P. Saville, Yufeng Wang, Jose L. Lopez-Ribot   +7 more
doaj   +1 more source

Faculty Opinions recommendation of Candidalysin is a fungal peptide toxin critical for mucosal infection.

, 2016
Xiaorong Lin, Xinping Xu
  +5 more sources

Screen for Candida albicans Virulence Factors that Modulate the Host Immune Response in the Larval Zebrafish [PDF]

Candida is one of the most frequent causes of bloodstream infections in the U.S. The first line of defense against these invasive infections is the innate immune system.
Blair, Bailey A
core   +1 more source

One Population, Multiple Lifestyles: Commensalism and Pathogenesis in the Human Mycobiome [PDF]

, 2023
Candida auris and Candida albicans can result in invasive fungal diseases. And yet, these species can stably and asymptomatically colonize human skin and gastrointestinal tracts.
Drummond, Rebecca A, Lionakis, Michail S, Proctor, Diana M, Segre, Julia A   +3 more
core   +1 more source

The role of the C. albicans transcriptional repressor NRG1 during filamentation and disseminated candidiasis is strain dependent

mSphere
Candida albicans is one of the most common causes of superficial and invasive fungal diseases in humans. Its ability to cause disease is closely linked to its ability to undergo a morphological transition from budding yeast to filamentous forms (hyphae ...
Rohan S. Wakade, Melanie Wellington, Damian J. Krysan   +2 more
doaj   +1 more source

Genomic interrogation of Candida albicans with relation to reproductive health and fertility [PDF]

, 2022
Candida albicans is a commensal yeast that can colonize a variety of host-associated niches including the human urogenital tract. It is the most common cause of fungal infections both superficial and systemic.
LUKE GOLBY
core  

The P-type calcium pump Spf1 regulates immune response by maintenance of the endoplasmic reticulum-plasma membrane contacts during Candida albicans systemic infection

Mycology
Spf1 is an important P-type ATPase in Candida albicans, which functions as an endoplasmic reticulum calcium pump to maintain calcium homoeostasis. The deficiency of Spf1 attenuates the virulence of C. albicans.
Yuchao Ji, Dou Chen, Menglin Shao, Zhuo Liu, Mingchun Li, Qilin Yu   +5 more
doaj   +1 more source

Author response: The Candida albicans virulence factor candidalysin polymerizes in solution to form membrane pores and damage epithelial cells

, 2022
C. Russell, Katherine G. Schaefer, Andrew C. Dixson, Amber L. H. Gray, Robert J. Pyron, Daiane S. Alves, Nicholas Moore, Elizabeth A. Conley, Ryan J Schuck, Tommi White, D. Thanh, Gavin M. King, Francisco N. Barrera   +12 more
openalex   +1 more source

918 Candidalysin, a virulence factor of Candida albicans, activates human keratinocytes through MAPK and NF-κB pathways [PDF]

, 2018
Pu Song, François Niyonsaba, Kazuhiro Okumura, Shigaku Ikeda, H. Ogawa   +4 more
openalex   +1 more source

Effects of Candidalysin Derived from Candida albicans on the Expression of Pro-Inflammatory Mediators in Human Gingival Fibroblasts [PDF]

Candida albicans (Ca) is frequently detected in the peri-implant sulcus with peri-implantitis, a major postoperative complication after oral implant therapy. However, the involvement of Ca in the pathogenesis of peri-implantitis remains unclear.
Hiroshima, Yuka, Ichikawa, Tetsuo, Kawano, Hiromichi, Kido, Jun-ichi, Murakami, Akikazu, Naruishi, Koji, Nishikawa, Yasufumi, Tomotake, Yoritoki, Yumoto, Hiromichi   +8 more
core