Results 51 to 60 of about 1,118 (147)
PLOS PathogensCandida albicans is a leading cause of intravascular catheter-related infections. The capacity for biofilm formation has been proposed to contribute to the persistence of this fungal pathogen on catheter surfaces. While efforts have been devoted to identifying microbial factors that modulate C.
Kuo-Yao Tseng +13 more
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Commensal colonization of <i>Candida albicans</i> in the mouse gastrointestinal tract is mediated via expression of candidalysin and adhesins. [PDF]
Microbiol SpectrMauk KE +8 more
europepmc +2 more sources
EMBO reports, 2023 AbstractThe peptide toxin candidalysin, secreted by Candida albicans hyphae, promotes stimulation of neutrophil extracellular traps (NETs). However, candidalysin alone triggers a distinct mechanism for NET‐like structures (NLS), which are more compact and less fibrous than canonical NETs.
Lucas Unger +12 more
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Candidalysin impedes the development of embryonic zebrafish (Danio rerio) [PDF]
, 2021 Abstract Candidalysin is a cytolytic peptide secreted by Candida albicans, an opportunistic human fungal pathogen that was widely spread in clinic and in the environment. However, its impacts on the development of aquatic organisms remain limited.
Jing Shen +7 more
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Alcohol-Related Liver Disease and Metabolic Dysfunction-Associated Steatotic Liver Disease: Molecular Pathogenesis and Therapeutic Interventions. [PDF]
MedComm (2020)Alcohol‐related (ALD) and metabolic dysfunction‐associated (MASLD) steatotic liver disease, while initiated by distinct etiologies (ethanol vs. metabolic stress), converge on shared core pathogenic pathways that drive progression. These include dysregulated lipid metabolism, programmed cell death, cellular senescence, gut dysbiosis, and immune ...
Tan Y, Hu Y, Yang Y, Chu H.
europepmc +2 more sources
Fungal Toxins and Host Immune Responses
Frontiers in Microbiology, 2021 Fungi are ubiquitous organisms that thrive in diverse natural environments including soils, plants, animals, and the human body. In response to warmth, humidity, and moisture, certain fungi which grow on crops and harvested foodstuffs can produce ...
Rhys Brown +3 more
doaj +1 more source
Dynamic expression of candidalysin facilitates oral colonization of Candida albicans in mice. [PDF]
Nat MicrobiolAbstract Candida albicans is a common fungal member of the human microbiota but can also cause infections via expression of virulence factors associated with the yeast-to-hyphae transition. The evolutionary selection pressure to retain these pathogenic traits for a commensal microorganism remains unclear.
Fróis-Martins R +14 more
europepmc +3 more sources
Frontiers in Cellular and Infection Microbiology, 2020 The mucosal surfaces of the human body are challenged by millions of microbes on a daily basis. Co-evolution with these microbes has led to the development of plastic mechanisms in both host and microorganisms that regulate the balance between preserving
Aize Pellon +2 more
doaj +1 more source
PLoS Pathogens, 2021 Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida albicans, results in significant quality-of-life issues for women worldwide.
Junyan Liu +16 more
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The role of Candida albicans candidalysin ECE1 gene in oral carcinogenesis [PDF]
Journal of Oral Pathology & Medicine, 2020 AbstractOral squamous cell carcinoma is associated with many known risk factors including tobacco smoking, chronic alcoholism, poor oral hygiene, unhealthy dietary habits and microbial infection. Previous studies have highlighted Candida albicans host tissue infection as a risk factor in the initiation and progression of oral cancer.
Engku Anis Fariha Engku Nasrullah Satiman +8 more
openaire +3 more sources