Results 51 to 60 of about 635 (146)

Candida albicans and oral carcinogenesis. A brief review. [PDF]

open access: yes, 2021
Current medical knowledge and research on patients’ management are still evolving, and several protocols on minimizing risk of infection by Candidaspp.among the population have developed.
Andrea Ballini   +5 more
core   +1 more source

Infection metallomics for critical care in the post‐COVID era

open access: yesMass Spectrometry Reviews, Volume 42, Issue 4, Page 1221-1243, July/August 2023., 2023
Abstract Infection metallomics is a mass spectrometry (MS) platform we established based on the central concept that microbial metallophores are specific, sensitive, noninvasive, and promising biomarkers of invasive infectious diseases. Here we review the in vitro, in vivo, and clinical applications of metallophores from historical and functional ...
Rutuja H. Patil   +2 more
wiley   +1 more source

A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis.

open access: yesPLoS Pathogens, 2021
Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida albicans, results in significant quality-of-life issues for women worldwide.
Junyan Liu   +16 more
doaj   +1 more source

It Takes Two to Tango: How a Dysregulation of the Innate Immunity, Coupled With Candida Virulence, Triggers VVC Onset

open access: yesFrontiers in Microbiology, 2021
Vulvovaginal candidiasis (VVC) is a symptomatic inflammation of the vagina mainly caused by C. albicans. Other species, such as C. parapsilosis, C. glabrata, C. tropicalis, and C. krusei, are mainly associated to the recurrent form of the disease (RVVC),
Andrea Ardizzoni   +4 more
doaj   +1 more source

New Insights in Candida albicans Innate Immunity at the Mucosa: Toxins, Epithelium, Metabolism, and Beyond

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
The mucosal surfaces of the human body are challenged by millions of microbes on a daily basis. Co-evolution with these microbes has led to the development of plastic mechanisms in both host and microorganisms that regulate the balance between preserving
Aize Pellon   +2 more
doaj   +1 more source

CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment [PDF]

open access: yes, 2019
This work was supported by the Intramural Research Program of the National Institute of Allergy and Infectious Disease, National Institutes of Health, as well as NIH grants awarded to TMH (R01 093808), SGF (R01AI124566) and SRL (R01CA161373).
A. Lira, Sergio   +15 more
core   +3 more sources

Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin [PDF]

open access: bronzeScience Immunology, 2017
Candidalysin, a hypha-associated fungal peptide, drives interleukin-17 responses to Candida albicans .
Akash Verma   +15 more
openalex   +7 more sources

Regulation of candidalysin underlies Candida albicans persistence in intravascular catheters by modulating NETosis

open access: goldPLOS Pathogens
Candida albicans is a leading cause of intravascular catheter-related infections. The capacity for biofilm formation has been proposed to contribute to the persistence of this fungal pathogen on catheter surfaces. While efforts have been devoted to identifying microbial factors that modulate C.
Kuo-Yao Tseng   +13 more
openalex   +4 more sources

Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis

open access: yesCell Reports, 2023
Summary: The fungal pathogen Candida albicans is linked to chronic brain diseases such as Alzheimer’s disease (AD), but the molecular basis of brain anti-Candida immunity remains unknown. We show that C. albicans enters the mouse brain from the blood and
Yifan Wu   +19 more
doaj  

Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers

open access: yesmBio, 2018
Life-threatening systemic infections often occur due to the translocation of pathogens across the gut barrier and into the bloodstream. While the microbial and host mechanisms permitting bacterial gut translocation are well characterized, these ...
Stefanie Allert   +16 more
doaj   +1 more source

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