Results 61 to 70 of about 1,663 (175)

A tale of two yeasts : Saccharomyces cerevisiae as a therapeutic against candidiasis [PDF]

, 2016
Funding DW is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (102549/Z/13/Z), a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology (097377/Z/11/Z), the MRC and University of ...
Wilson, Duncan
core   +1 more source

Candida albicans Yeast, Pseudohyphal, and Hyphal Morphogenesis Differentially Affects Immune Recognition [PDF]

, 2017
The authors thank Amy Whittington for preliminary experiments on in vitro induction of pseudohyphae and Mihai Netea for discussions. The authors also thank Michael Weig for the pga29 strains. Funding NG and AW were supported by the Wellcome Trust (086827,
Bailey, Bates, Bates, Beaussart, Berman, Birse, Blasi, Brown, Bulawa, Calera, Cambi, Chen, Chen, Cheng, Cheng, Chiani, Courjol, Dalle, De Boer, Dennehy, d’Ostiani, Endres, Erwig, Fidel, Gantner, Gantner, Ghannoum, Gow, Gow, Gow, Gow, Gow, Gudlaugsson, Harris, Heinsbroek, Hobson, Hoebe, Hornby, Hornby, Hosseinzadeh, Jackson, Jouault, Kohatsu, Kullberg, Kullberg, Lee, Linden, Lo, Lu, Matuschak, McKenzie, Medzhitov, Merson-Davies, Mora-Montes, Mora-Montes, Moyes, Moyes, Moyes, Moyes, Munro, Murad, Netea, Netea, Netea, Pappas, Plaine, Rubin-Bejerano, Saville, Sellam, Sudbery, Sudbery, Sundstrom, Torosantucci, Van De Veerdonk, Van Der Graaf, Vavala, Wagener, Wheeler, Zhao, Zheng   +79 more
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IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis [PDF]

, 2016
Signaling through the IL-17 receptor (IL-17R) is required to prevent oropharyngeal candidiasis (OPC) in mice and humans. However, the IL-17-responsive cell type(s) that mediate protection are unknown.
Brane, Lucas, Bruno, Vincent M., Childs, Erin E., Coleman, Bianca M., Conti, Heather R., Cruz, J. Agustin, Daugherty, Sean, Filler, Scott G., Gaffen, Sarah L., Garg, Abhishek V., Hendricks, Matthew R., Hise, Amy G., Hunter, Joseph P., Kolls, Jay K., Mengesha, Bemnet G., Naglik, Julian R., Richardson, Jonathan P., Saevig, Danielle L., Sinha, Satrajit, Solis, Norma, Verma, Akash H.   +20 more
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Integrating Candida albicans metabolism with biofilm heterogeneity by transcriptome mapping [PDF]

, 2016
This work was supported by the Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377/Z/11/Z. We are grateful to microbiology colleagues throughout Scotland for clinical isolates collection.Peer reviewedPublisher ...
Abeln, Sanne, Brandt, Bernd W., Burgess, Karl V, Heringa, Jaap, Jones, Brian L., Kean, Ryan, May, Ali, Munro, Carol A., Rajendran, Ranjith, Ramage, Gordon, Sherry, Leighann, Williams, Craig   +11 more
core   +4 more sources

Nucleic acids enrichment of fungal pathogens to study host-pathogen interactions [PDF]

, 2019
Fungal infections, ranging from superficial to life-threatening infections, represent a major public health problem that affects 25% of the worldwide population.
Coucke, Paul, Guillemyn, Brecht, Rodriguez Sánchez, Antonio, Vaneechoutte, Mario   +3 more
core   +1 more source

The cell biology of the Trichosporon-Host interaction [PDF]

, 2017
Fungi of the genus Trichosporon are increasingly recognized as causative agents of superficial and invasive fungal disease in humans. Although most species are considered commensals of the human skin and gastrointestinal tract, these basidiomycetes are ...
Akoumianaki, Alby, Aratani, Arendrup, Arikawa, Arts, Bentubo, Cheng, Childers, Chitasombat, Choi, Colombo, Cong, Crawford, da Silva Dantas, de Almeida Junior, de Almeida Junior, Di Bonaventura, Ene, Ene, Erwig, Fernandes, Figueiredo-Carvalho, Fonseca, Fontaine, Gacser, Garlanda, Gish, Gouba, Gravelat, Gresnigt, Higashino-Kameda, Hole, Iliev, Karashima, Kontoyiannis, Kronstad, Krysan, Lamas, Lanternier, Lee, Li, Lyman, Lyman, Marine, Moalli, Monari, Moyes, Moylett, Muranaka, Nosanchuk, Pande, Picard, Piccioni, Quintin, Reddy, Richardson, Rieber, Rodriguez-Tudela, Rohatgi, Saeed, Sandai, Sasaki, Saunders, Schwartz, Sokol, Sriswasdi, Sugita, Sugita, Sun, Suzuki, Taylor-Smith, Thywißen, Walsh, Walsh, Wynne, Yauch, Zaragoza, Zelante, Zhang, Zhang, Zhang   +81 more
core   +1 more source

Dynamic expression of candidalysin facilitates oral colonization of Candida albicans in mice. [PDF]

Nat Microbiol
Abstract Candida albicans is a common fungal member of the human microbiota but can also cause infections via expression of virulence factors associated with the yeast-to-hyphae transition. The evolutionary selection pressure to retain these pathogenic traits for a commensal microorganism remains unclear.
Fróis-Martins R, Lagler J, Schille TB, Elshafee O, Martinez de San Vicente K, Mertens S, Stokmaier M, Kilb I, Sertour N, Bachellier-Bassi S, Mogavero S, Sanglard D, d'Enfert C, Hube B, LeibundGut-Landmann S.   +14 more
europepmc   +3 more sources

Candida albicans Enhances Protease Activity and Activates MyD88-Dependent IL-1β Production in Human Keratinocytes. [PDF]

Mycoses
ABSTRACT Background Atopic dermatitis (AD) is a common chronic skin disorder characterised by a highly inflamed local environment and elevated epidermal proteolytic activity. Changes in the skin mycobiome have been observed in this disease, specifically Candida albicans colonization positively correlating with AD severity, yet the mechanisms by which ...
Wang J, Gow NAR, Brewer MG.
europepmc   +2 more sources

Gaining insights from Candida biofilm heterogeneity: one size does not fit all [PDF]

, 2018
Despite their clinical significance and substantial human health burden, fungal infections remain relatively under-appreciated. The widespread overuse of antibiotics and the increasing requirement for indwelling medical devices provides an opportunistic ...
Delaney, Christopher, Kean, Ryan, McLean, William, Metcalfe, Rebecca, Rajendran, Ranjith, Ramage, Gordon, Sherry, Leighann, Thomas, Rachael, Williams, Craig   +8 more
core   +4 more sources

Medical mycology and fungal immunology : new research perspectives addressing a major world health challenge [PDF]

, 2016
N.A.R.G. is supported by grants from The Wellcome Trust and MRC. M.G.N. is supported by an ERC consolidator grant (no.
Brown GD, Jenkinson HF, Kennedy MJ, Mihai G. Netea, Neil A. R. Gow, Romani L, Van der Graaf CA   +6 more
core   +1 more source