Results 71 to 80 of about 1,624 (196)

Management of alcoholic hepatitis: A clinical perspective

Liver International, Volume 43, Issue 10, Page 2078-2095, October 2023., 2023
Abstract Alcohol‐associated liver disease is the primary cause of liver‐related mortality worldwide and one of the most common indications for liver transplantation. Alcoholic hepatitis represents the most acute and severe manifestation of alcohol‐associated liver disease and is characterized by a rapid onset of jaundice with progressive inflammatory ...
Philipp Kasper, Sonja Lang, Hans‐Michael Steffen, Münevver Demir   +3 more
wiley   +1 more source

The Missing Link between Candida albicans Hyphal Morphogenesis and Host Cell Damage [PDF]

, 2016
Funding: Our own work was funded by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (102549/Z/13/Z), a Wellcome Trust ISSF (RG12723-14), the MRC and University of Aberdeen (MR/N006364/1) (DW); Medical Research ...
Hube, Bernhard, Naglik, Julian R., Wilson, Duncan   +2 more
core   +2 more sources

Alcohol, the gut microbiome, and liver disease

Journal of Gastroenterology and Hepatology, Volume 38, Issue 8, Page 1205-1210, August 2023., 2023
Abstract The microorganisms inhabiting our gastrointestinal tract are critical for human health. Chronic heavy alcohol use can modulate the composition and function of the gut microbiota, thereby exacerbating end‐organ damage via the gut–brain axis and the gut–liver axis.
Michael H Jew, Cynthia L Hsu
wiley   +1 more source

Oral Fungal Alterations in Patients with COVID‐19 and Recovered Patients

Advanced Science, Volume 10, Issue 19, July 6, 2023., 2023
This research characterizes oral mycobiome in coronavirus disease 2019 (COVID‐19) patients and recovered COVID‐19 patients, constructs and validates the diagnostic model for COVID‐19, successfully diagnoses suspected cases with positive immunoglobulin G antibody as confirmed patients, and depicts the correlations between the oral microbiome and ...
Xiaobo Hu, Haiyu Wang, Bo Yu, Jia Yu, Haifeng Lu, Junyi Sun, Ying Sun, Yawen Zou, Hong Luo, Zhaohai Zeng, Shanshuo Liu, Yan Jiang, Zhongwen Wu, Zhigang Ren   +13 more
wiley   +1 more source

Candida albicans Yeast, Pseudohyphal, and Hyphal Morphogenesis Differentially Affects Immune Recognition [PDF]

, 2017
The authors thank Amy Whittington for preliminary experiments on in vitro induction of pseudohyphae and Mihai Netea for discussions. The authors also thank Michael Weig for the pga29 strains. Funding NG and AW were supported by the Wellcome Trust (086827,
Bailey, Bates, Bates, Beaussart, Berman, Birse, Blasi, Brown, Bulawa, Calera, Cambi, Chen, Chen, Cheng, Cheng, Chiani, Courjol, Dalle, De Boer, Dennehy, d’Ostiani, Endres, Erwig, Fidel, Gantner, Gantner, Ghannoum, Gow, Gow, Gow, Gow, Gow, Gudlaugsson, Harris, Heinsbroek, Hobson, Hoebe, Hornby, Hornby, Hosseinzadeh, Jackson, Jouault, Kohatsu, Kullberg, Kullberg, Lee, Linden, Lo, Lu, Matuschak, McKenzie, Medzhitov, Merson-Davies, Mora-Montes, Mora-Montes, Moyes, Moyes, Moyes, Moyes, Munro, Murad, Netea, Netea, Netea, Pappas, Plaine, Rubin-Bejerano, Saville, Sellam, Sudbery, Sudbery, Sundstrom, Torosantucci, Van De Veerdonk, Van Der Graaf, Vavala, Wagener, Wheeler, Zhao, Zheng   +79 more
core   +2 more sources

Infection metallomics for critical care in the post‐COVID era

Mass Spectrometry Reviews, Volume 42, Issue 4, Page 1221-1243, July/August 2023., 2023
Abstract Infection metallomics is a mass spectrometry (MS) platform we established based on the central concept that microbial metallophores are specific, sensitive, noninvasive, and promising biomarkers of invasive infectious diseases. Here we review the in vitro, in vivo, and clinical applications of metallophores from historical and functional ...
Rutuja H. Patil, Dominika Luptáková, Vladimír Havlíček   +2 more
wiley   +1 more source

Modulation of C. albicans-Induced Immune Response in Vaginal Epithelial Cells by Garcinoic Acid. [PDF]

Microorganisms
Sabbatini S, Zatini L, Narducci E, Rosati L, Ardizzoni A, Mencacci A, Rende M, Pericolini E, Galli F, Bartolini D, Monari C.   +10 more
europepmc   +3 more sources

A tale of two yeasts : Saccharomyces cerevisiae as a therapeutic against candidiasis [PDF]

, 2016
Funding DW is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (102549/Z/13/Z), a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology (097377/Z/11/Z), the MRC and University of ...
Wilson, Duncan
core   +1 more source

A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis.

PLoS Pathogens, 2021
Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida albicans, results in significant quality-of-life issues for women worldwide.
Junyan Liu, Hubertine M E Willems, Emily A Sansevere, Stefanie Allert, Katherine S Barker, David J Lowes, Andrew C Dixson, Zhenbo Xu, Jian Miao, Christian DeJarnette, Helene Tournu, Glen E Palmer, Jonathan P Richardson, Francisco N Barrera, Bernhard Hube, Julian R Naglik, Brian M Peters   +16 more
doaj   +1 more source

It Takes Two to Tango: How a Dysregulation of the Innate Immunity, Coupled With Candida Virulence, Triggers VVC Onset

Frontiers in Microbiology, 2021
Vulvovaginal candidiasis (VVC) is a symptomatic inflammation of the vagina mainly caused by C. albicans. Other species, such as C. parapsilosis, C. glabrata, C. tropicalis, and C. krusei, are mainly associated to the recurrent form of the disease (RVVC),
Andrea Ardizzoni, Robert T. Wheeler, Robert T. Wheeler, Eva Pericolini, Eva Pericolini   +4 more
doaj   +1 more source