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Endometriosis: candidate genes [PDF]
Human Reproduction Update, 2001 Endometriosis is generally regarded as a benign disease but it does exhibit some characteristics reminiscent of malignancy. This raises the possibility that, like malignant diseases, the development of endometriosis may involve the acquisition of somatic genetic alterations in genes that regulate cell growth and differentiation.
I G, Campbell, E J, Thomas
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Candidate gene prioritization with Endeavour [PDF]
Nucleic Acids Research, 2016 Genomic studies and high-throughput experiments often produce large lists of candidate genes among which only a few are truly relevant to the disease, phenotype, or biological process of interest. Gene prioritization tackles this problem by ranking candidate genes by profiling candidates across multiple genomic data sources and ...
Tranchevent, Léon-Charles +6 more
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RNA-Seq Transcriptome Analysis of Potato with Differential Tolerance to Bentazone Herbicide
Agronomy, 2021 Potato (Solanum tuberosum), an important food crop worldwide, is threatened by broadleaf weeds. Bentazone is an effective herbicide for controlling weeds; however, as a photosynthesis inhibitor, it can also affect potato plants.
Jing Guo +5 more
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Using genomic annotations increases statistical power to detect eGenes. [PDF]
, 2016 MotivationExpression quantitative trait loci (eQTLs) are genetic variants that affect gene expression. In eQTL studies, one important task is to find eGenes or genes whose expressions are associated with at least one eQTL. The standard statistical method
Duong, Dat +6 more
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Logical Operation Based Literature Association with Genes and its application, PosMed. [PDF]
, 2010 PosMed prioritizes candidate genes for positional cloning by employing our original database search engine GRASE, which uses an inferential process similar to an artificial neural network comprising documental neurons (or 'documentrons') that ...
Akihiro Matsushima +9 more
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Prediction of gene–phenotype associations in humans, mice, and plants using phenologs [PDF]
, 2013 All authors are with the Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA.
Laurent, Jon M. +4 more
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Analysis of SNP-SNP interactions and bone quantitative ultrasound parameter in early adulthood
BMC Medical Genetics, 2017 Background Osteoporosis individual susceptibility is determined by the interaction of multiple genetic variants and environmental factors. The aim of this study was to conduct SNP-SNP interaction analyses in candidate genes influencing heel quantitative ...
María Correa-Rodríguez +5 more
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Searching for "monogenic diabetes" in dogs using a candidate gene approach [PDF]
, 2014 BACKGROUND: Canine diabetes is a common endocrine disorder with an estimated breed-related prevalence ranging from 0.005% to 1.5% in pet dogs. Increased prevalence in some breeds suggests that diabetes in dogs is influenced by genetic factors and ...
Catchpole, B +7 more
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Journal of Mental Health and Human Behaviour, 2018 Background and Objectives: Reasonable amount of literature has been accumulated over the years to indicate that the binge drinkers might be different from the group which does not have any history of binging.
Abhishek Ghosh +3 more
doaj +1 more source
miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. [PDF]
, 2019 ObjectiveOnset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped-MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small ...
Aaen, Gregory +31 more
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