Results 11 to 20 of about 728,220 (269)

Analysis of SNP-SNP interactions and bone quantitative ultrasound parameter in early adulthood

open access: yesBMC Medical Genetics, 2017
Background Osteoporosis individual susceptibility is determined by the interaction of multiple genetic variants and environmental factors. The aim of this study was to conduct SNP-SNP interaction analyses in candidate genes influencing heel quantitative ...
María Correa-Rodríguez   +5 more
doaj   +1 more source

The clinical, personality, and genetic correlates of binge drinking: A controlled association study from India

open access: yesJournal of Mental Health and Human Behaviour, 2018
Background and Objectives: Reasonable amount of literature has been accumulated over the years to indicate that the binge drinkers might be different from the group which does not have any history of binging.
Abhishek Ghosh   +3 more
doaj   +1 more source

Deciphering the Genetic Alterations in PIK3CA Gene Interacting Network and Their Putative Association with Breast Cancer: A Computational Approach [PDF]

open access: yesMiddle East Journal of Cancer
Background: Cancer is a polygenic complex disorder involving a network of genes. The phosphatidylinositol 3-kinase (PIK3CA) has been reported as an oncogene that plays a role in many cancer types.
Sivapriya Dayakar   +4 more
doaj   +1 more source

Allelic distribution of BDNF Val66Met polymorphism in healthy Romanian volunteers

open access: yesTranslational Neuroscience, 2016
Population stratification of functional gene polymorphisms is a potential confounding factor in genetic association studies. The Val66Met (rs6265) single-nucleotide polymorphism in the brain-derived neurotrophic factor gene (BDNF) exhibits one of the ...
Vulturar Romana   +5 more
doaj   +1 more source

CD14 GENE AS A CANDIDATE GENE FOR IMMUNOMODULATION : A REVIEW [PDF]

open access: yesExploratory Animal and Medical Research, 2012
CD14 molecule and CD14 gene has been characterized in various livestock species. Structural analysis of CD14 molecule and CD14 gene encoding it is helpful for understanding its function for immuno-modulation. CD14 gene has been observed to be highly
Aruna Pa   +4 more
doaj  

Bioinformatics methods for identifying candidate disease genes

open access: yesHuman Genomics, 2006
With the explosion in genomic and functional genomics information, methods for disease gene identification are rapidly evolving. Databases are now essential to the process of selecting candidate disease genes.
van Driel Marc A, Brunner Han G
doaj   +1 more source

Mapping Novel Loci and Candidate Genes Associated with Cadmium Content in Maize Using Genome-Wide Association Analysis

open access: yesAgriculture
Cadmium is a toxic, carcinogenic element that threatens food safety due to its tendency to be absorbed by plants along with essential nutrients. This study conducted a genome-wide association study (GWAS) using SNP genotyping data from 170 natural maize ...
Ruiqiang Lai   +11 more
doaj   +1 more source

Candidate and non-candidate genes in behavior genetics

open access: yesCurrent Opinion in Neurobiology, 2013
In this review we discuss recent developments in psychiatric genetics: on the one hand, studies using whole genome approaches (genome-wide association studies (GWAS) and exome sequencing) are coming close to finding genes and molecular variants that contribute to disease susceptibility; on the other candidate genes, such as the serotonin transporter ...
Flint, Jonathan, Munafò, Marcus R
openaire   +5 more sources

Genetic dissection of branch architecture in oilseed rape (Brassica napus L.) germplasm

open access: yesFrontiers in Plant Science, 2022
Branch architecture is an important factor influencing rapeseed planting density, mechanized harvest, and yield. However, its related genes and regulatory mechanisms remain largely unknown.
Ying Wang   +10 more
doaj   +1 more source

Genomic adaptation of Ethiopian indigenous cattle to high altitude

open access: yesFrontiers in Genetics, 2022
The mountainous areas of Ethiopia represent one of the most extreme environmental challenges in Africa faced by humans and other inhabitants. Selection for high-altitude adaptation is expected to have imprinted the genomes of livestock living in these ...
Endashaw Terefe   +10 more
doaj   +1 more source

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