Deciphering the Genetic Alterations in PIK3CA Gene Interacting Network and Their Putative Association with Breast Cancer: A Computational Approach [PDF]
Middle East Journal of CancerBackground: Cancer is a polygenic complex disorder involving a network of genes. The phosphatidylinositol 3-kinase (PIK3CA) has been reported as an oncogene that plays a role in many cancer types.
Sivapriya Dayakar +4 more
doaj +1 more source
Allelic distribution of BDNF Val66Met polymorphism in healthy Romanian volunteers
Translational Neuroscience, 2016 Population stratification of functional gene polymorphisms is a potential confounding factor in genetic association studies. The Val66Met (rs6265) single-nucleotide polymorphism in the brain-derived neurotrophic factor gene (BDNF) exhibits one of the ...
Vulturar Romana +5 more
doaj +1 more source
An integrated genomic approach for the study of mandibular prognathism in the European seabass (Dicentrarchus labrax) [PDF]
, 2016 Skeletal anomalies in farmed fish are a relevant issue affecting animal welfare and health and causing significant economic losses. Here, a high-density genetic map of European seabass for QTL mapping of jaw deformity was constructed and a genome-wide ...
Babbucci, Massimiliano +7 more
core +2 more sources
Bioinformatics methods for identifying candidate disease genes
Human Genomics, 2006 With the explosion in genomic and functional genomics information, methods for disease gene identification are rapidly evolving. Databases are now essential to the process of selecting candidate disease genes.
van Driel Marc A, Brunner Han G
doaj +1 more source
CD14 GENE AS A CANDIDATE GENE FOR IMMUNOMODULATION : A REVIEW [PDF]
Exploratory Animal and Medical Research, 2012 CD14 molecule and CD14 gene has been characterized in various livestock species. Structural analysis of CD14 molecule and CD14 gene encoding it is helpful for understanding its function for immuno-modulation. CD14 gene has been observed to be highly
Aruna Pa +4 more
doaj
Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1 [PDF]
, 2017 The clinical and electroencephalographic features of a canine generalized myoclonic epilepsy with photosensitivity and onset in young Rhodesian Ridgeback dogs (6 wk to 18 mo) are described.
Arumilli, Meharji +21 more
core +1 more source
Modeling the functional genomics of autism using human neurons. [PDF]
, 2012 Human neural progenitors from a variety of sources present new opportunities to model aspects of human neuropsychiatric disease in vitro. Such in vitro models provide the advantages of a human genetic background combined with rapid and easy manipulation,
Chen, L +10 more
core +1 more source
Frontiers in Genetics, 2022 Bone health is particularly important for high-yielding commercial layer chickens. The keel of poultry is an extension of the abdomen side of the sternum along the sagittal plane and is one of the most important bones.
Zhihao Zhang +7 more
doaj +1 more source
Finding New Cell Wall Regulatory Genes in Populus trichocarpa Using Multiple Lines of Evidence. [PDF]
, 2019 Understanding the regulatory network controlling cell wall biosynthesis is of great interest in Populus trichocarpa, both because of its status as a model woody perennial and its importance for lignocellulosic products.
Chen, Jin-Gui +23 more
core +3 more sources
AgricultureCadmium is a toxic, carcinogenic element that threatens food safety due to its tendency to be absorbed by plants along with essential nutrients. This study conducted a genome-wide association study (GWAS) using SNP genotyping data from 170 natural maize ...
Ruiqiang Lai +11 more
doaj +1 more source