Results 121 to 130 of about 43,946 (263)

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9‐tetrahydrocannabinol in BV‐2 microglial cells [PDF]

open access: bronze, 2011
Ana Juknat   +7 more
openalex   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

open access: yesBritish Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez   +13 more
wiley   +1 more source

COVID-19 and Cannabidiol: Results from a Rapid Review

open access: diamond, 2021
Manuela Holst   +2 more
openalex   +1 more source

A Retrospective Cross‐Sectional Study of 142 Patients in a Multidisciplinary Tuberous Sclerosis Clinic

open access: yesClinical Genetics, EarlyView.
We found key differences between tuberous sclerosis patients with TSC1 and TSC2 variants. Patients carrying TSC2 variants had more severe and earlier‐onset symptoms. We also identified two distinct clinical subgroups which follow different disease courses: one characterized by predominant renal involvement and the other by more pronounced neurological ...
Hila Weisblum Neuman   +6 more
wiley   +1 more source

Evidence of Cannabidiol Effectiveness Associated or Not with Tetrahydrocannabinol in Topical Administration: A Scope Review

open access: yesPharmaceuticals
Cannabis sativa is a plant of the Cannabaceae family, whose molecular composition is known for its vast pharmacological properties. Cannabinoids are the molecules responsible for Cannabis sativa potential effects, especially tetrahydrocannabinol and ...
Ana Laura Masquetti Fava   +8 more
doaj   +1 more source

Effects of cannabidiol plus naltrexone on motivation and ethanol consumption [PDF]

open access: bronze, 2018
Adrián Viudez‐Martínez   +4 more
openalex   +1 more source

CBD Hemp Pharming in Illinois: Working to Legitimize an Enduringly Illicit Crop

open access: yesCulture, Agriculture, Food and Environment, EarlyView.
ABSTRACT Based on interviews and participant observation activities conducted in 2024, this article investigates the perspectives and experiences of Illinois farmers cultivating CBD (cannabidiol) hemp. The 2018 U.S. Farm Bill legalized hemp, defined as cannabis containing < 0.3% delta‐9 tetrahydrocannabinol (THC), the intoxicating compound found in ...
Megan A. Styles, Courtney R. Roberts
wiley   +1 more source

Expanding Production of Cannabis in Iowa [PDF]

open access: yes, 2015
Following passage of Senate Bill 2360 “Medical Cannabidiol Act” in Iowa, possession of Cannabidiol Oil become legal for patients who suffered from intractable epilepsy.
DeWall, Christine   +4 more
core   +1 more source

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