Results 161 to 170 of about 43,946 (263)

Full‐Spectrum Medicinal Cannabis Plant Extract 0.08% THC (NTI164) Improves Symptoms of Rett Syndrome: An Open‐Label Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim The aim of this Phase I/II open‐label study was to assess the safety and efficacy of NTI164, a novel full‐spectrum medicinal cannabis plant extract 0.08% Δ‐9‐tetrahydrocannabinol (THC), in Rett syndrome (RTT). Methods Eleven female participants (5–16 years) with a pathogenic variant in the MECP2 gene were recruited to this study, receiving
B. A. Keating, Y. Ogru, T. G. Duthy, L. Douglas, K. Lichkus, E. Isikgel, M. C. Fahey, C. Ellaway   +7 more
wiley   +1 more source

Safety of synthetic cannabidiol as a Novel food pursuant to Regulation (EU) 2015/2283. [PDF]

EFSA J
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, Bohn T, Cámara M, Castenmiller J, De Henauw S, Jos Á, Maciuk A, Mangelsdorf I, McNulty B, Naska A, Pentieva K, Siani A, Thies F, Aguilera-Gómez M, Cubadda F, Marchelli R, McArdle HJ, Moldeus P, Neuhäuser-Berthold M, Schlatter JR, Siskos A, Trezza V, Albert O, Beneventi E, Favata A, Kass GEN, Laganaro M, Magani M, Garciarena IN, Pieger AM, Rossi A, Hirsch-Ernst KI.   +33 more
europepmc   +2 more sources

Acute Effects of Oral Cannabinoids on Sleep and High‐Density EEG in Insomnia: A Pilot Randomised Controlled Trial

Journal of Sleep Research, EarlyView.
ABSTRACT Cannabinoids, particularly Δ9‐tetrahydrocannabinol (THC) and cannabidiol (CBD), have gained popularity as alternative sleep aids; however, their effects on sleep architecture and next‐day function remain poorly understood. Here, in a pilot trial, we examined the effects of a single oral dose containing 10 mg THC and 200 mg CBD (THC/CBD) on ...
Anastasia Suraev, Iain S. McGregor, Danielle McCartney, Nathaniel S. Marshall, Chien‐Hui Kao, Rick Wassing, Angela L. D'Rozario, Keith K. H. Wong, Brendon J. Yee, Sheila Sivam, Richard C. Kevin, Ryan Vandrey, Christopher Irwin, Christopher J. Gordon, Delwyn Bartlett, Jonathon C. Arnold, Ronald R. Grunstein, Camilla M. Hoyos   +17 more
wiley   +1 more source

Availability and affordability of cannabinoids for epilepsy treatment across different geographic settings—A survey from the ILAE Plant‐Based Therapy Task Force

Epilepsia, EarlyView.
Kollencheri Puthenveettil Vinayan, Ali Akbar Asadi‐Pooya, Aruna Setumadhava Jyotsna, Nithya N. Kumar, Siegward‐M. Elsas, Cecilie Johannessen Landmark, Motlalepula Matsabisa, Boulenouar Mesraoua, Finbar O'Callaghan, Elizabeth Thiele, Chunbo Zhang, Kate Riney   +11 more
wiley   +1 more source

Differences in Plasma Exposure of Cannabidiol and Cannabidiolic Acid Following Oral Administration to Horses

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT There has been a growing interest in the use of cannabinoids in horses in recent years. Several studies have reported on the pharmacokinetics of cannabidiol (CBD) in horses. However, cannabidiolic acid (CBDA) has received less attention, despite limited evidence suggesting clinically beneficial effects in other species.
Carl Ekstrand, Peter Michanek, Elin Hernlund, Ronette Gehring, Kristin Spjut, Matilda Salomonsson   +5 more
wiley   +1 more source

Neural correlates of interactions between cannabidiol and Δ⁹‐tetrahydrocannabinol in mice: implications for medical cannabis [PDF]

, 2015
Stephanie M. Todd, Jonathon C. Arnold
openalex   +1 more source

Kinetic studies of the interaction of cannabinoids with singlet oxygen

Photochemistry and Photobiology, EarlyView.
Graphical abstract showing sensitization of singlet oxygen by xanthone and its subsequent quenching by cannabinoids. Abstract The kinetics of the interaction of several cannabinoids with singlet oxygen have been examined in acetonitrile solution using laser flash photolysis techniques and using xanthone as a singlet oxygen sensitizer.
Carly J. Frank, Neeraj Joshi, Tony Durst, Juan C. Scaiano   +3 more
wiley   +1 more source

Combination of cannabidiol with low‑dose naltrexone increases the anticancer action of chemotherapy in vitro and in vivo

, 2022
Wai M. Liu, Nadine Hall, Harry Liu, Francis Hood, Angus Dalgleish   +4 more
openalex   +2 more sources

Cannabis‐Derived Compounds Against Plasmodium sp.: A Systematic Review of Preclinical Studies

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objective This study aims to evaluate preclinical studies on the effects and toxicity of cannabis‐derived compounds against Plasmodium sp. Methods A literature search was conducted in Web of Science, PubMed, Scopus and LILACS databases until December 2024. Studies that assessed the activity or toxicity of cannabis against Plasmodium sp.
Tácio de Mendonça Lima, Luann Wendel Pereira de Sena, Ana Carolina Corrêa de Sousa, Gabriel Rodrigues Martins de Freitas, Inajara Rotta, Marília Berlofa Visacri   +5 more
wiley   +1 more source

When the Going Gets Weird, The Weird Turn Pro*: Management Best Practices in the Age of Medicinal Marijuana [PDF]

, 2020
Winn, John I., JD, LLM
core   +1 more source