Results 21 to 30 of about 23,909 (233)
Analyzing cannabinoid-induced abnormal behavior in a zebrafish model.
PLoS ONE, 2020 In this study, we investigated locomotor activity and responses to repeated light and dark stimuli to assess cannabinoid-induced abnormal behavior in zebrafish larvae (Danio rerio), as an alternative to standard rodent models.
Akihiro Hasumi +2 more
doaj +1 more source
Pronounced State-Level Disparities in Prescription of Cannabinoids to Medicaid Patients
Medical Cannabis and Cannabinoids, 2023 Introduction: Dronabinol is approved in the USA for chemotherapy-induced nausea as well as vomiting and HIV-induced anorexia, while cannabidiol is primarily approved for childhood epileptic disorders Lennox-Gastaut and Dravet syndrome.
Edward Y. Liu +2 more
doaj +1 more source
The Lancet Regional Health. Europe, 2023 Summary: Background: Painful knee osteoarthritis (KOA) is common, pharmacological treatment, however, is often hampered by limited tolerability. Cannabidiol, which preclinically showed anti-inflammatory, analgesic activity, could supplement established ...
Sibylle Pramhas +6 more
doaj +1 more source
The parabss1 Drosophila melanogaster as Model for Chronic Nociception: Insights Into Cannabidiol Analgesic Effects. [PDF]
Eur J PainABSTRACT Background Chronic pain, which is often unrelated to ongoing injury, is poorly understood and difficult to treat. Genetic studies have identified voltage‐gated sodium (Nav) channels, particularly gain‐of‐function mutations such as L858F and R1150W in human NaV1.7, as involved in the development of chronic pain. Methods A chronic pain model was
Malta SM +7 more
europepmc +2 more sources
Successful use of pure cannabidiol for the treatment of super-refractory status epilepticus
Epilepsy and Behavior Case Reports, 2018 We present the case of a child with long-standing, super-refractory status epilepticus (SRSE) who manifested prompt and complete resolution of SRSE upon exposure to pure cannabidiol.
Rajsekar R. Rajaraman +2 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2021 Cannabidiol, a compound of Cannabis sativa, has been proposed as an alternative treatment of schizophrenia. Preclinical and clinical data have suggested that cannabidiol shares more similarity with atypical antipsychotics than typical, both of which are ...
Ana Caroline Brambilla Falvella +12 more
doaj +1 more source
Specific features of cannabidiol metabolism and excretion during long-term consumption of cannabis [PDF]
International Journal of Minor Fruits, Medicinal and Aromatic PlantsThe purpose of this study was to characterize the key patterns of cannabidiol metabolism and elimination. To fulfil this purpose, the study employed the latest scientific sources for the last 5-6 years from authoritative scientometric databases and ...
Oles-Pylyp Hasiuk
doaj +1 more source
Disposition of a single oral dose of a cannabidiol medication in healthy cats
Frontiers in Veterinary Science, 2023 The historical use of the marijuana plant for medicinal purposes is long. One of the historical uses has been for the treatment of epilepsy. Recently, the Food and Drug Administration has approved a highly purified cannabidiol medication for the add on ...
Tom Jukier +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source