Results 161 to 170 of about 2,668,334 (282)

An Introduction to the Endogenous Cannabinoid System.

Biological Psychiatry, 2016
Hui-Chen Lu, K. Mackie
semanticscholar   +1 more source

Progress in Gastroparesis Management: From Pharmacotherapy to Interventional Treatments

JGH Open, Volume 10, Issue 3, March 2026.
ABSTRACT Gastroparesis is a sensorimotor condition characterized by delayed gastric emptying without any obvious mechanical obstruction. Common symptoms include early satiety, nausea, vomiting, belching, and bloating. The most frequent causes of gastroparesis are diabetes, idiopathic factors, and post‐surgical complications.
Ganesh Kumar, Yash Shah, Ume Rooman, Ravi Patel, Shireen Asifa, Qais M. Salah, Dushyant Singh Dahiya, Arkadeep Dhali, Camelia Arsene, Meer Ali   +9 more
wiley   +1 more source

Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent, Selective, and CNS-Penetrant Agonists for the Cannabinoid Receptor 2. [PDF]

J Med Chem
Haymer DH, Duncan RA, Rodriguez AL, Han A, Lindsay RJ, Wijesiri NK, Thompson Gray A, Krishnan S, Qi A, Brown BP, Boutaud O, Engers DW, Jones CK, Niswender CM, Lindsley CW, Bender AM.   +15 more
europepmc   +1 more source

Cannabigerol Modulates Cannabinoid Receptor Type 2 Expression in the Spinal Dorsal Horn and Attenuates Neuropathic Pain Models. [PDF]

Pharmaceuticals (Basel)
Rezende B, Fernandes GG, de Simas Gonçalves VM, Nascimento GG, Marques KL, de Oliveira BCCA, Dos Santos YB, de Andrade MEB, Calumbi KS, Maia EP, Trefilio LM, Antunes F, Fontes-Dantas FL, Montes GC.   +13 more
europepmc   +1 more source

Suicide attempt and paranoia persisting for 28 days following heavy delta‐9‐tetrahydrocannabinolic acid and tetrahydrocannabinol use: A case report

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Background Cannabis contains various cannabinoids, with Δ9‐tetrahydrocannabinol (Δ9‐THC) being the primary psychoactive compound. A non‐psychoactive precursor called Δ9‐tetrahydrocannabinolic acid (THC‐A) is converted to Δ9‐THC slowly over time or rapidly when heated. Cannabis use is linked to psychotic outcomes, with increased risk associated
Daniel Greer, Prithula Dey, Caitlin E. Kulig   +2 more
wiley   +1 more source

Activity of protein kinase C controls the efficacy of cannabinoid receptor type 1 in the medial prefrontal cortex after neuropathic pain. [PDF]

J Neurophysiol
Chao D, Liu Y, Cheng T, Hogan QH, Pan B.
europepmc   +1 more source

Cannabinoid Receptor 2: Potential Role in Immunomodulation and Neuroinflammation

Journal of Neuroimmune Pharmacology, 2013
Slava Rom, Y. Persidsky
semanticscholar   +1 more source

Current and Emerging Pharmacologic Therapies for Diabetic Retinopathy

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 3, March 2026.
ABSTRACT Diabetic retinopathy, a prevalent microvascular complication of diabetes mellitus, is a leading cause of blindness among adults in developed countries. Risk factors include prolonged duration of diabetes, elevated glycosylated hemoglobin levels, hypertension, and dyslipidemia, with rapid glucose reduction also increasing risk for developing ...
Jennifer N. Clements, Julia Mesawich, Cassandra Twisdale   +2 more
wiley   +1 more source

Characterization of binding kinetics and intracellular signaling of new psychoactive substances targeting cannabinoid receptor using transition-based reweighting method. [PDF]

Elife
Dutta S, Shukla D.
europepmc   +1 more source

Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities

Philosophical Transactions of the Royal Society B: Biological Sciences, 2012
R. Pertwee
semanticscholar   +1 more source