Results 111 to 120 of about 1,296,096 (233)

Cannabinoid hyperemesis syndrome: genetic susceptibility to toxic exposure

Frontiers in Toxicology
Cannabinoid hyperemesis syndrome presents as a complex of symptoms and signs encompassing nausea, vomiting, abdominal pain, and hot water bathing behavior, most typically in a heavy cannabis user.
Ethan B. Russo, Venetia L. Whiteley
doaj   +1 more source

Synthetic cannabinoid receptor agonists are monoamine oxidase-A selective inhibitors. [PDF]

FEBS J, 2023
Hindson SA, Andrews RC, Danson MJ, van der Kamp MW, Manley AE, Sutcliffe OB, Haines TSF, Freeman TP, Scott J, Husbands SM, Blagbrough IS, Anderson JLR, Carbery DR, Pudney CR.   +13 more
europepmc   +1 more source

Circadian rhythms and chronotherapy in Alzheimer's disease: Mechanisms and therapeutic implications

Neuroprotection, Volume 4, Issue 3, Page 229-247, September 2026.
Circadian dysregulation contributes to Alzheimer's disease through sleep disruption, clock‐gene dysfunction, neuroinflammation, impaired proteostasis, and metabolic imbalance. These alterations promote cognitive decline and disease progression, while circadian biomarkers and chronotherapeutic interventions offer opportunities for precision diagnosis ...
Bivek Singh, Filippo Pigazzani, Roberto Manfredini   +2 more
wiley   +1 more source

Cannabinoids Block Fat-induced Incretin Release via CB1-dependent and CB1-independent Pathways in Intestinal Epithelium

Gastro Hep Advances
Background and Aims: Glucose homeostasis is regulated by a dynamic interplay between hormones along the gastro-insular axis. For example, enteroendocrine L- and K- cells that line the intestine produce the incretins glucagon-like peptide-1 (GLP1) and ...
Pedro Antonio Perez, Mark Benjamin Wiley, Alexandros Makriyannis, Nicholas Vincent DiPatrizio   +3 more
doaj   +1 more source

Interaction of Synthetic Cannabinoid Receptor Agonists with Cannabinoid Receptor I: Insights into Activation Molecular Mechanism. [PDF]

Int J Mol Sci, 2023
Gavryushov S, Bashilov A, Cherashev-Tumanov KV, Kuzmich NN, Burykina TI, Izotov BN.   +5 more
europepmc   +1 more source

CANNABINOIDS REGULATE TYPE 1 CANNABINOID RECEPTOR EXPRESSION IN CELL CULTURE MODELS OF HUNTINGTON'S DISEASE

, 2012
Type 1 cannabinoid receptor (CB1) levels decline in the striatum of animal models of Huntington’s disease (HD) and in the brains of human patients suffering from HD prior to other pathogenic changes.
Laprairie, Robert
core  

UK Medical Cannabis Registry: A Clinical Outcomes Analysis for Autism Spectrum Disorder

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
A case series studying outcomes up to 18 months in autistic patients from the UK Medical Cannabis Registry. ABSTRACT Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with distressed behaviors and psychological challenges.
Arushika Aggarwal, Simon Erridge, Madhur Varadpande, Evonne Clarke, Katy McLachlan, Ross Coomber, Muhammed Asghar, Urmila Bhoskar, Matthieu Crews, Andrea De Angelis, Muhammad Imran, Fariha Kamal, Laura Korb, Gracia Mwimba, Simmi Sachdeva‐Mohan, Gabriel Shaya, James J. Rucker, Mikael H. Sodergren   +17 more
wiley   +1 more source

Fatal Overdose with the Cannabinoid Receptor Agonists MDMB-4en-PINACA and 4F-ABUTINACA: A Case Report and Review of the Literature. [PDF]

Toxics, 2023
Simon G, Kuzma M, Mayer M, Petrus K, Tóth D.   +4 more
europepmc   +1 more source

Psychiatric effects of cannabidiol, cannabinol, and tetrahydrocannabinol: A narrative review of clinical evidence and risk profiles

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.
Abstract Cannabinoid products are increasingly used worldwide despite limited psychiatric evidence. This narrative review synthesizes preclinical and clinical evidence on cannabidiol (CBD), cannabinol (CBN), and tetrahydrocannabinol (THC) to clarify their distinct psychiatric profiles and discuss how current evidence may inform ongoing clinical and ...
Yasuhiro Kishi, Ichiro Takumi, Kakusho Chigusa Nakajima‐Ohyama   +2 more
wiley   +1 more source

Cannabinoid Modulation of Excitability and Short-Term Neuronal Dynamics in the Dorsal and Ventral Hippocampus

Biology
Endocannabinoids, acting primarily through CB1 receptors, are critical modulators of neuronal activity, influencing cognitive functions and emotional processing.
Giota Tsotsokou, Ioanna-Maria Sotiropoulou, Klearchos Stampolitis, George D. Oikonomou, Aikaterini-Paraskevi Avdi, Costas Papatheodoropoulos   +5 more
doaj   +1 more source