Results 191 to 200 of about 28,905 (252)
Melatonin as a protector against endocrine disruption across tissues: A systematic review
Graphical Abstract showing the biological mechanisms by which melatonin protects tissues against endocrine disruption. Abstract Endocrine‐disrupting chemicals (EDCs) are widespread environmental pollutants that interfere with hormonal homeostasis and contribute to multisystem toxicity.
Clenie Isingizwe +2 more
wiley +1 more source
Beyond prediction: unveiling the prognostic power of μ-opioid and cannabinoid receptors, alongside immune mediators, in assessing the severity of SARS-CoV-2 infection. [PDF]
Tavakoli-Yaraki M +11 more
europepmc +1 more source
Clickable nucleoside phosphoramidites can be incorporated into oligonucleotides via solid‐phase synthesis (SPOS), enabling rapid and site‐specific post‐functionalization using bioorthogonal reactions. This review highlights their design, synthetic accessibility, and SPOS incorporation requirements, along with the kinetics and efficiency of post ...
Sébastien Depienne +3 more
wiley +1 more source
IUPHAR review- Preclinical models of neuropathic pain: Evaluating multifunctional properties of natural cannabinoid receptors ligands. [PDF]
Benamar K.
europepmc +1 more source
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Prostaglandins and Other Lipid Mediators, 2002
Cannabinoid receptors were named because they have affinity for the agonist delta9-tetrahydrocannabinol (delta9-THC), a ligand found in organic extracts from Cannabis sativa. The two types of cannabinoid receptors, CB1 and CB2. are G protein coupled receptors that are coupled through the Gi/o family of proteins to signal transduction mechanisms that ...
Allyn Howlett
exaly +3 more sources
Cannabinoid receptors were named because they have affinity for the agonist delta9-tetrahydrocannabinol (delta9-THC), a ligand found in organic extracts from Cannabis sativa. The two types of cannabinoid receptors, CB1 and CB2. are G protein coupled receptors that are coupled through the Gi/o family of proteins to signal transduction mechanisms that ...
Allyn Howlett
exaly +3 more sources
Cannabinoids, cannabinoid receptors and tinnitus
Hearing Research, 2016One hypothesis suggests that tinnitus is a form of sensory epilepsy, arising partly from neuronal hyperactivity in auditory regions of the brain such as the cochlear nucleus and inferior colliculus. Although there is currently no effective drug treatment for tinnitus, anti-epileptic drugs are used in some cases as a potential treatment option. There is
Paul F, Smith, Yiwen, Zheng
openaire +2 more sources
Cannabinoid receptors in atherosclerosis
Current Opinion in Lipidology, 2006Recent findings suggesting that cannabinoid receptors are potential targets for the treatment of atherosclerosis are reviewed.Cannabinoids, such as Delta9-tetrahydrocannabinol, the major psychoactive compound of marijuana, their synthetic analogs and endogenous cannabinoid ligands, produce their biological effects by interacting with specific receptors.
Sabine, Steffens, Francois, Mach
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Cannabinoid receptors in the kidney
Current Opinion in Nephrology and Hypertension, 2016The endocannabinoid system modulates cell signaling targets that are essential for energy homeostasis. Endocannabinoids bind to G protein-coupled receptors in the central nervous system and periphery, including the kidney. Modulation of cannabinoid receptor 1 (CB1) and CB2 activity in the kidney in diabetes and obesity has been identified as potential ...
Hryciw, Deanne H, McAinch, Andrew J
openaire +3 more sources
Cannabinoid receptors and immunity
Immunology Today, 1998Abstract Marijuana cannabinoids are both psychoactive and immunoactive. Here, we will review evidence that cannabinoids modulate immunity and that cannabinoid receptors and endogenous ligands are expressed in immune tissues. Clues will also be presented concerning the role of the cannabinoid system in immune regulation and the possible molecular ...
T W, Klein, C, Newton, H, Friedman
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