Results 191 to 200 of about 56,803 (285)

Mechanistic origin of partial agonism of tetrahydrocannabinol for cannabinoid receptors. [PDF]

J Biol Chem, 2022
Dutta S, Selvam B, Das A, Shukla D.
europepmc   +1 more source

Correspondence of Basal Forebrain Resting‐State Functional Connectivity and Cerebral Glucose Metabolism Alterations With Neurotransmitter Maps in Alzheimer's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
Altered functional connectivity of basal forebrain subregions (Ch1‐3, Ch4) and widespread cerebral hypometabolism were identified in Alzheimer's disease using simultaneous PET/MRI. Spatial correspondence with normative neurotransmitter receptor and transporter maps suggested that serotonergic and dopaminergic systems may contribute to AD‐related ...
Yujie He, Hanxiao Xue, Sheng Bi, Yan Wang, Xiaocao Liu, Yixia Li, Zhigeng Chen, Dongdong Rong, Bixiao Cui, Jie Ma, Shaozhen Yan, Jie Lu   +11 more
wiley   +1 more source

Prenatal Downregulation of CB₁ Cannabinoid Receptors in the Mouse Prefrontal Cortex Disrupts Cortical Lamination and Induces a Transcriptional Signature Associated with Social Interaction Deficits. [PDF]

J Neurosci
Simón-Sánchez S, den Boon F, García-Rincón D, Skrempou G, Paraíso-Luna J, Aguilera A, Nieto M, Werkman TR, Guzmán M, Chameau P, Galve-Roperh I.   +10 more
europepmc   +1 more source

Repeated Tetrahydrocannabinol Injections Induce Tolerance but Do Not Disrupt Ongoing Behaviour Upon Withdrawal in Male and Female Rats With Inflammatory Pain

European Journal of Pain, Volume 30, Issue 5, May 2026.
ABSTRACT Background Many people use cannabis to self‐medicate for pain. Little is known about the impact of pain on tolerance and spontaneous withdrawal to delta‐9‐tetrahydrocannabinal (THC), the primary psychoactive compound in cannabis. Our previous research with the opioid morphine suggests persistent pain will increase the magnitude and duration of
Michael M. Morgan, Christa M. Hickey
wiley   +1 more source

Cannabinoid Receptors Reduced Early Brain Damage by Regulating NOX-2 and the NLRP3 Inflammasome in an Animal Model of Intracerebral Hemorrhage. [PDF]

CNS Neurosci Ther
Martínez-Torres AM, Ramírez-Celis C, Morán J.   +2 more
europepmc   +1 more source

Activation of Peripheral Cannabinoid Receptors Synergizes the Effect of Systemic Ibuprofen in a Pain Model in Rat. [PDF]

Pharmaceuticals (Basel), 2022
Díaz-Reval MI, Cárdenas Y, Huerta M, Trujillo X, Sánchez-Pastor EA, González-Trujano ME, Virgen-Ortíz A, Pérez-Hernández MG.   +7 more
europepmc   +1 more source

Potential of solid‐state microwaves in lab‐scale chemical‐process development

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 5, Page 1077-1093, May 2026.
Abstract BACKGROUND The integration of a solid‐state microwave (MW) generator into a newly designed, versatile MW reactor ensures improved energy efficiency, precise process control and broader application potential. In its most particular feature, the device supports the modification of dielectric‐radiation orientation and can be operated under ...
Christian Cravotto, Clelia Aimone, Giorgio Capaldi, Giorgio Grillo, Giancarlo Cravotto   +4 more
wiley   +1 more source

Psychiatric Disorders and Cannabinoid Receptors. [PDF]

Adv Exp Med Biol, 2021
Joshi N, Onaivi ES.
europepmc   +1 more source

Innate Lymphoid Cells in Tissue Homeostasis and Diseases

MedComm, Volume 7, Issue 5, May 2026.
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan, Heyang Sun, Chenning Li, Qianya Hong, Shuainan Zhu, Ying Yu, Hao Zhang, Kefang Guo   +7 more
wiley   +1 more source

Corticosterone stimulates synthesis of 2-arachidonoylglycerol via putative membrane-bound glucocorticoid receptors and inhibits GABA release via CB1 cannabinoid receptors in the ventrolateral periaqueductal gray. [PDF]

Mol Pharmacol
Coutens B, Bouchet CA, Patti LC, McPherson KB, Boston BS, Jewett DC, Ingram SL.   +6 more
europepmc   +1 more source