Results 1 to 10 of about 50,545 (304)
Cannabinoids Reduce Melanoma Cell Viability and Do Not Interfere with Commonly Used Targeted Therapy in Metastatic Melanoma In Vivo and In Vitro [PDF]
Biology, 2023 Background: Cannabinoids are mainly used for recreational purposes, but also made their way into oncology, since these substances can be taken to increase appetite in tumour cachexia.
Georg Richtig +8 more
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Frontiers in Cellular Neuroscience, 2023 IntroductionFragile X syndrome (FXS), resulting from a mutation in the Fmr1 gene, is the most common monogenic cause of autism and inherited intellectual disability.
Gabriele Giua +13 more
doaj +1 more source
Sex-specific divergent maturational trajectories in the postnatal rat basolateral amygdala
iScience, 2022 Summary: In rodents and humans, the basolateral amygdala (BLA), essential for emotional behaviors, is profoundly reorganized during adolescence. We compared in both sexes the morphology, neuronal, and synaptic properties of BLA neurons in rats at puberty
Pauline Guily +3 more
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Promotion de la santé et prévention des maladies chroniques au Canada, 2023 IntroductionLa pandémie de COVID-19 a eu des effets négatifs généralisés sur la santé, notamment une perte de sécurité matérielle et une exacerbation des maladies mentales chez les populations à risque.
Stephanie Lake +3 more
doaj +1 more source
Shifts in medical cannabis use in Canada during the COVID-19 pandemic
Health Promotion and Chronic Disease Prevention in Canada, 2023 IntroductionThe COVID-19 pandemic has had widespread secondary negative health impacts including loss of material security and exacerbation of mental illness in at-risk populations.
Stephanie Lake +3 more
doaj +1 more source
Cancers, 2021 Cannabinoids, active components of the plant Cannabis sativa, had been used for centuries in ancient medicine as therapeutic remedies for a variety of conditions, before becoming stigmatized due to their psychoactive effects [...]
Marco Falasca, Mauro Maccarrone
openaire +2 more sources
Puff, Puff, Don’t Pass: harm reduction for cannabis use during a viral respiratory pandemic
Harm Reduction Journal, 2023 Background Prior to the COVID-19 pandemic, cannabis use social practices often involved sharing prepared cannabis (joints/blunts/cigarettes) and cannabis-related paraphernalia.
Ryan D. Assaf +5 more
doaj +1 more source
Medical Cannabis and Cannabinoids, 2018 Cannabinoid hyperemesis syndrome (CHS) is a paradoxical condition in which a long-term cannabis user suffers an episode of intractable vomiting that may last days separated by longer asymptomatic periods of weeks or months. Cannabinoids are often utilized for their antiemetic properties, so CHS can be a puzzling condition, and the diagnosis of CHS may ...
Joseph V. Pergolizzi Jr. +2 more
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Biomolecules, 2023 In this review article, we embark on a thorough exploration of cannabinoids, compounds that have garnered considerable attention for their potential therapeutic applications. Initially, this article delves into the fundamental background of cannabinoids,
Victor Voicu +9 more
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Heteroadamantyl Cannabinoids [PDF]
Journal of Medicinal Chemistry, 2010 The aliphatic side chain plays a pivotal role in determining the cannabinergic potency of tricyclic classical cannabinoids. We have synthesized a series of analogues in which the C3 position is substituted either directly or through a one-carbon atom linker with an adamantylamine or with an oxa- or an oxazaadamantane. The oxaadamantane pharmacophore in
Darryl D, Dixon +8 more
openaire +2 more sources