Identification and quantification of cannabinol as a biomarker for local hemp retting in an ancient sedimentary record by HPTLC-ESI-MS [PDF]
, 2020 Cannabis products have been used in various fields of everyday life for many centuries, and applications in folk medicine and textile production have been well-known for many centuries.
Csuk, René +6 more
core +2 more sources
Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage [PDF]
, 2012 BACKGROUND: The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations.
Bechmann, Ingo Jürgen +8 more
core +11 more sources
Frontiers in Behavioral Neuroscience, 2019 Heavy cannabis consumption among adolescents is associated with significant and lasting neurobiological, psychological and health consequences that depend on the age of first use.
Milene Borsoi +13 more
doaj +1 more source
Endocannabinoid-related compounds in gastrointestinal diseases [PDF]
, 2018 The endocannabinoid system (ECS) is an endogenous signalling pathway involved in the control of several gastrointestinal (GI) functions at both peripheral and central levels.
Alessandra, D'Alessandro +7 more
core +1 more source
The impact of phyto- and endo-cannabinoids on central nervous system diseases：A review
Journal of Traditional and Complementary Medicine, 2023 Background and aim: Cannabis sativa L. is a medicinal plant with a long history. Phyto-cannabinoids are a class of compounds from C. sativa L. with varieties of structures. Endocannabinoids exist in the human body.
Shan-Shan Zhang +5 more
doaj +1 more source
The evolution and comparative neurobiology of endocannabinoid signalling [PDF]
, 2012 CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A. +4 more
core +1 more source
In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Cannabis sativa
Scientific Reports, 2020 The Cannabis sativa plant contains more than 120 cannabinoids. With the exceptions of ∆9-tetrahydrocannabinol (∆9-THC) and cannabidiol (CBD), comparatively little is known about the pharmacology of the less-abundant plant-derived (phyto) cannabinoids ...
Ayat Zagzoog +8 more
semanticscholar +1 more source
Medical use of cannabis: italian and european legislation [PDF]
, 2018 This review illustrates some brief considerations of the medical use of cannabis recently issued in Italy. History and uses of cannabis throughout centuries and different countries are illustrated together with a description of botany and active ...
Di Luca, A. +3 more
core +1 more source
Self-administration of edible Δ9-tetrahydrocannabinol and associated behavioral effects in mice [PDF]
, 2019 Background With increasing access to legal cannabis across the globe, it is imperative to more closely study its behavioral and physiological effects.
Boehm, Stephen L., II +3 more
core +2 more sources
The Highs and Lows of Cannabis in Cancer Treatment and Bone Marrow Transplantation
Rambam Maimonides Medical Journal, 2020 In the last decade, we have observed an increased public and scientific interest in the clinical applications of medical cannabis. Currently, the application of cannabinoids in cancer patients is mainly due to their analgesic and anti-emetic effects. The
Osnat Almogi-Hazan +3 more
doaj +1 more source