Results 71 to 80 of about 50,545 (304)

Differentiating Nonsuicidal Self‐Injury (NSSI) From Suicide Attempts in Adolescents: A Pilot Study

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Background Differentiating between nonsuicidal self‐injury (NSSI) and suicide attempts (SA) in adolescents is crucial due to distinct underlying motivations, treatment needs, and potential outcomes associated with each behavior.
María Posada‐Ayala   +9 more
wiley   +1 more source

Long‐Term Follow‐Up of Patients with Mass Social Media‐Induced Illness Presenting with Functional Tic‐like Behaviors

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Only little is known about the prognosis of functional tic‐like behaviors (FTLB), especially in the subgroup of patients with mass social media‐induced illness (MSMI‐FTLB). Objectives To provide data of long‐term follow‐up (FU) of a carefully characterized group of patients with MSMI‐FTLB to identify influencing factors such as ...
L. Kathrin Hartung   +5 more
wiley   +1 more source

Bridging the Regulatory Chasm in Investigator‐Initiated Human Subject Cannabis Research

open access: yes
Clinical Pharmacology &Therapeutics, EarlyView.
Heather M. Barkholtz, William Naviaux
wiley   +1 more source

Gray Matter Volume Loss in Parkinson's Disease Psychosis and Cannabinoid Receptor Gene Expression in the Brain

open access: yesMovement Disorders, EarlyView.
Abstract Background Serotonergic and dopaminergic pathways are implicated in Parkinson's disease psychosis (PDP), but preliminary evidence also implicates the endocannabinoid system (ECS). Objectives We examined the association of gray matter volume loss in PDP patients with brain expression of the genes coding for CB1 (cannabinoid type 1) and CB2 ...
Sara Pisani   +3 more
wiley   +1 more source

Cannabinoids [PDF]

open access: yesJournal of Pain and Symptom Management, 2013
Paul, Howard   +4 more
openaire   +2 more sources

An Open‐Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease

open access: yesMovement Disorders, EarlyView.
Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar   +15 more
wiley   +1 more source

Exploration of the Phytochemical and Antidiabetic Properties of Teucrium polium: A Natural Asset for Type 2 Diabetes Management

open access: yesChemistryOpen, EarlyView.
Teucrium polium shows antidiabetic activity with its phytochemical composition and biological activities. The essential oil is rich in carvacrol, thymol, γ‐terpinene, and o‐cymene, while the aqueous and hydroethanolic extracts are characterized by poliumoside, verbascoside, isorhamnetin‐3‐O‐rutinoside, and apigenin‐7‐rutinoside. Antioxidant activity is
Hajar El Ouadni   +10 more
wiley   +1 more source

Optimization of the supercritical extraction and decarboxylation process of industrial hemp

open access: yesJournal of CO2 Utilization
Cannabinoids are the main active ingredients of Cannabis sativa L., obtained by a suitable extraction method and decarboxylation, in which the acid forms of the cannabinoids are converted into active forms.
Taja Žitek Makoter   +4 more
doaj   +1 more source

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

open access: yesChemistryOpen, EarlyView.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali   +4 more
wiley   +1 more source

Cannabinoids on the Brain

open access: yesThe Scientific World Journal, 2002
Cannabis has a long history of consumption both for recreational and medicinal uses. Recently there have been significant advances in our understanding of how cannabis and related compounds (cannabinoids) affect the brain and this review addresses the ...
Andrew J. Irving   +2 more
doaj   +1 more source

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