Results 41 to 50 of about 462,841 (245)

Indirect caffeine modeling in an urban river

open access: yesRevista Ambiente & Água, 2022
Caffeine is used worldwide as a chemical tracer to identify anthropic pressures on urban water resources. Nevertheless, its quantification demands great financial investments.
Luis Otávio Miranda Peixoto   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Image dehazing using two‐dimensional canonical correlation analysis

open access: yesIET Computer Vision, 2015
Image dehazing is an important issue that interests both image processing and computer vision. In this study, image dehazing is modelled as an example‐based learning problem, and a novel dehazing algorithm using two‐dimensional (2D) canonical correlation
Liqian Wang, Liang Xiao, Zhihui Wei
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A New Robust Deep Canonical Correlation Analysis Algorithm for Small Sample Problems

open access: yesIEEE Access, 2019
As a nonlinear feature learning method, deep canonical correlation analysis (DCCA) has got a great success in computer vision. Compared with kernel methods, deep neural networks can more easily process large amounts of training data and do not require ...
Yan Liu, Yun Li, Yun-Hao Yuan, Hui Zhang
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Minimax estimation in sparse canonical correlation analysis

open access: yes, 2015
Canonical correlation analysis is a widely used multivariate statistical technique for exploring the relation between two sets of variables. This paper considers the problem of estimating the leading canonical correlation directions in high-dimensional ...
Gao, Chao   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

In silico drug repositioning based on integrated drug targets and canonical correlation analysis

open access: yesBMC Medical Genomics, 2022
Background Besides binding to proteins, the most recent advances in pharmacogenomics indicate drugs can regulate the expression of non-coding RNAs (ncRNAs).
Hailin Chen, Zuping Zhang, Jingpu Zhang
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Home - About - Disclaimer - Privacy