Results 41 to 50 of about 396,548 (332)
Components of the canonical and non-canonical Wnt pathways are not mis-expressed in pituitary tumors. [PDF]
PLoS ONE, 2013 IntroductionCanonical and non-canonical Wnt pathways are involved in the genesis of multiple tumors; however, their role in pituitary tumorigenesis is mostly unknown.ObjectiveThis study evaluated gene and protein expression of Wnt pathways in pituitary ...
Leandro Machado Colli +7 more
doaj +1 more source
Differential expression of canonical and non‐canonical Wnt ligands in ameloblastoma [PDF]
Journal of Oral Pathology & Medicine, 2011 J Oral Pathol Med (2012) 41: 332–339Background: Canonical and non‐canonical Wnt signaling pathways modulate diverse cellular processes during embryogenesis and post‐natally. Their deregulations have been implicated in cancer development and progression. Wnt signaling is essential for odontogenesis.
Siar, C.H. +7 more
openaire +2 more sources
Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer
Molecular Cancer, 2010 Background Wnt factors control cell differentiation through semi-independent molecular cascades known as the β-catenin-dependent (canonical) and -independent (non-canonical) Wnt signalling pathways.
López-Otín Carlos +13 more
doaj +1 more source
Role of Wnt Signaling in Adult Hippocampal Neurogenesis in Health and Disease
Frontiers in Cell and Developmental Biology, 2020 Neurogenesis persists during adulthood in the dentate gyrus of the hippocampus. Signals provided by the local hippocampal microenvironment support neural stem cell proliferation, differentiation, and maturation of newborn neurons into functional dentate ...
Sebastian B. Arredondo +3 more
doaj +1 more source
Primary cilia are not required for normal canonical Wnt signaling in the mouse embryo. [PDF]
PLoS ONE, 2009 Sonic hedgehog (Shh) signaling in the mouse requires the microtubule-based organelle, the primary cilium. The primary cilium is assembled and maintained through the process of intraflagellar transport (IFT) and the response to Shh is blocked in mouse ...
Polloneal Jymmiel R Ocbina +2 more
doaj +1 more source
Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling*
Journal of Biological Chemistry, 2005 The loss of the SOST gene product sclerostin leads to sclerosteosis characterized by high bone mass. In this report, we found that sclerostin could antagonize canonical Wnt signaling in human embryonic kidney A293T cells and mouse osteoblastic MC3T3 ...
Xiaofeng Li +7 more
semanticscholar +1 more source
PLoS Genetics, 2018 Van Gogh-like (Vangl) and Prickle (Pk) are core components of the non-canonical Wnt planar cell polarity pathway that controls epithelial polarity and cell migration.
Remco A Mentink +6 more
doaj +1 more source
Canonical WNT Signalling Controls Hair Follicle Spacing [PDF]
Cell Adhesion & Migration, 2007 Canonical WNT signals play an important role in hair follicle development. In addition to being crucial for epidermal appendage initiation, they control the interfollicular spacing pattern and contribute to the spatial orientation and largely parallel alignment of hair follicles.
Thomas, Schlake, Stefanie, Sick
openaire +2 more sources
Canonical Wnt pathway gene expression and their clinical correlation in oral squamous cell carcinoma
Indian Journal of Dental Research, 2018 Aim: The aim of this study is to explore the prognostic significance and clinicopathological correlations of the Wnt pathway genes in a cohort of surgically treated patients with oral squamous cell carcinoma (OSCC) patients.
Madhulaxmi +8 more
semanticscholar +1 more source
Wnt Signaling Regulates Multipolar-to-Bipolar Transition of Migrating Neurons in the Cerebral Cortex
Cell Reports, 2015 The precise timing of pyramidal cell migration from the ventricular germinal zone to the cortical plate is essential for establishing cortical layers, and migration errors can lead to neurodevelopmental disorders underlying psychiatric and neurological ...
Michael Boitard +8 more
doaj +1 more source