Results 1 to 10 of about 190,613 (246)

The Phenomenon of Drug Emulsion Carriers Compaction during Their Movement in Microstructures

open access: yesPharmaceutics, 2022
The greatest challenges of modern pharmacology are the design of drugs with the highest possible efficacy of an active substance and with the lowest possible invasiveness for the whole organism.
Mariola M. Błaszczyk   +2 more
doaj   +1 more source

Endothelial Ion Channels and Cell-Cell Communication in the Microcirculation

open access: yesFrontiers in Physiology, 2022
Endothelial cells in resistance arteries, arterioles, and capillaries express a diverse array of ion channels that contribute to Cell-Cell communication in the microcirculation.
William F. Jackson
doaj   +1 more source

Proinflammatory mediators, TNFα, IFNγ, and thrombin, directly induce lymphatic capillary tube regression

open access: yesFrontiers in Cell and Developmental Biology, 2022
In this work, we sought to investigate the direct effects of proinflammatory mediators on lymphatic endothelial cell (LEC) capillaries and whether they might induce regression.
Scott S. Kemp   +4 more
doaj   +1 more source

Increased 20-HETE Signaling Suppresses Capillary Neurovascular Coupling After Ischemic Stroke in Regions Beyond the Infarct

open access: yesFrontiers in Cellular Neuroscience, 2021
Neurovascular coupling, the process by which neuronal activity elicits increases in the local blood supply, is impaired in stroke patients in brain regions outside the infarct.
Zhenzhou Li   +7 more
doaj   +1 more source

Capillary muscle [PDF]

open access: yesProceedings of the National Academy of Sciences, 2015
Significance The force generated by a muscle decreases when its contraction velocity increases. This rheology follows the heuristic Hill’s equation. Here, we design and study a capillary analog in which the myosin–actin interaction is replaced by the wetting affinity between a Newtonian silicone oil and a steel rod.
Cohen, Caroline   +3 more
openaire   +3 more sources

Risk factors for anesthesia-associated postoperative capillary leakage after thoracoscopic surgery in neonates: A single-center observational study

open access: yesFrontiers in Pediatrics, 2023
BackgroundThoracoscopy is considered the surgical method of choice for addressing a wide range of conditions in neonates. However, there is a lack of experience in anesthesia management for this procedure.
Heqi Liu   +3 more
doaj   +1 more source

Spatiotemporal microvascular changes following contusive spinal cord injury

open access: yesFrontiers in Neuroanatomy, 2023
Microvascular integrity is disrupted following spinal cord injury (SCI) by both primary and secondary insults. Changes to neuronal structures are well documented, but little is known about how the capillaries change and recover following injury ...
Nicole J. Smith   +7 more
doaj   +1 more source

Is the microvasculature tone increasing with arterial hypertension?

open access: yesAlʹmanah Kliničeskoj Mediciny, 2019
Rationale: An increase in vascular tone is believed to be a major factor leading to arterial hypertension (AH). There are no means for a direct measurement of the vascular tone in clinical practice.
D. A. Rogatkin   +7 more
doaj   +1 more source

Long-Term Running Exercise Delays Age-Related Changes in White Matter in Rats

open access: yesFrontiers in Aging Neuroscience, 2020
Running exercise, one of the strategies to protect brain function, has positive effects on neurons and synapses in the cortex and hippocampus. However, white matter, as an important structure of the brain, is often overlooked, and the effects of long ...
Lin Chen   +20 more
doaj   +1 more source

Retinal oxygen supply shaped the functional evolution of the vertebrate eye

open access: yeseLife, 2019
The retina has a very high energy demand but lacks an internal blood supply in most vertebrates. Here we explore the hypothesis that oxygen diffusion limited the evolution of retinal morphology by reconstructing the evolution of retinal thickness and the
Christian Damsgaard   +16 more
doaj   +1 more source

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