Results 91 to 100 of about 64,951 (237)

Enhanced Early Detection of Allergic Rhinitis: A Prospective Study on a Symptom‐Based Predictive Model

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Allergic rhinitis (AR) and non‐allergic rhinitis (NAR) share overlapping symptoms but differ in pathophysiology and treatment. Current AR diagnosis relies on skin prick testing (SPT) and serum IgE quantification, both of which are complex.
Ke‐Zhang Zhu   +4 more
wiley   +1 more source

Capsaicin and carcinogenesis. Conflicting evidence regarding effects on carcinogenesis [PDF]

open access: yesFarmacja Polska
Study subject. Effect of capsaicin on tumorigenesis. Plants of the Capsicum family including chili peppers are one of the oldest domesticated crops. The constituents of chili peppers, particularly capsaicin, have become the subject of intense research ...
Krzysztof Mariusz Halczuk   +1 more
doaj   +1 more source

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): short‐term peri‐operative analgesic use

open access: yesAnaesthesia, EarlyView.
Summary Introduction An increasing proportion of complex surgical procedures are being performed in the UK as day‐cases, with variable and limited follow up. Discharge prescriptions must provide adequate analgesia, while considering the safety of the patient and public, following best practice guidance and good opioid stewardship.
Anna Ratcliffe   +2083 more
wiley   +1 more source

Efficacy and Safety of Diclofenac + Capsaicin Gel in Patients with Acute Back/Neck Pain: A Multicenter Randomized Controlled Study

open access: yesPain and Therapy, 2020
Introduction Back and neck pain are common musculoskeletal disorders. Topical non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used to reduce pain and inflammation with fewer systemic side effects and drug interactions compared with oral ...
Hans-Georg Predel   +4 more
doaj   +1 more source

Understand spiciness: mechanism of TRPV1 channel activation by capsaicin. [PDF]

open access: yes, 2017
Capsaicin in chili peppers bestows the sensation of spiciness. Since the discovery of its receptor, transient receptor potential vanilloid 1 (TRPV1) ion channel, how capsaicin activates this channel has been under extensive investigation using a variety ...
Yang, Fan, Zheng, Jie
core   +2 more sources

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Impacts of chronic stress on urinary bladder function & recovery through modification of PACAP signaling [PDF]

open access: yes, 2016
Stress can cause or contribute to bladder dysfunction though specific effects remain unclear. Individuals with interstitial cystitis (IC)/bladder pain syndrome (BPS) experience increased symptom severity with stress, including pain and increased urgency ...
Mathews, Morgan E
core   +1 more source

Effects of Basic Slag, Aggregate Size and Groundwater Treatments on the Production of Chilli in Acid Sulfate Soils in a Simulation Study [PDF]

open access: yes, 2008
A simulation study was conducted to evaluate the effects of basic slag (BS10 and BS20: basic slag 10 and 20 t ha-1), aggregate size (A20 and A30: aggregate sizes of soil, less than 20 and 20-30 mm) and groundwater depth (Gw0: no influence of groundwater ...
Bhuiyan, Md. Mukaddas Ali   +3 more
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Capsaicin suppresses liver fat accumulation in high-fat diet-induced NAFLD mice

open access: yesAnimal Cells and Systems, 2020
Dietary capsaicin exhibits anti-steatosis activity in obese mice. High-fat diet (HFD)-induced mice is a highly studied approach to develop non-alcoholic fatty liver disease (NAFLD).
Mi Kyung Shin, Soo-Man Yang, In-Seob Han
doaj   +1 more source

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