Results 61 to 70 of about 216,910 (182)
Elasticity Theory and Shape Transitions of Viral Shells
, 2005 Recently, continuum elasticity theory has been applied to explain the shape transition of icosahedral viral capsids - single-protein-thick crystalline shells - from spherical to buckled/faceted as their radius increases through a critical value ...
B. K. Ganser +9 more
core +1 more source
How simple can a model of an empty viral capsid be? Charge distributions in viral capsids
, 2012 We investigate and quantify salient features of the charge distributions on viral capsids. Our analysis combines the experimentally determined capsid geometry with simple models for ionization of amino acids, thus yielding the detailed description of ...
A Lošdorfer Božič +37 more
core +1 more source
Properties and Functions of the Dengue Virus Capsid Protein.
Annual Review of Virology, 2016 Dengue virus affects hundreds of millions of people each year around the world, causing a tremendous social and economic impact on affected countries.
Laura A. Byk, A. Gamarnik
semanticscholar +1 more source
A Liquid Crystal Model of Viral DNA Encapsidation
, 2017 A liquid crystal continuum modeling framework for icosahedra bacteriophage viruses is developed and tested. The main assumptions of the model are the chromonic columnar hexagonal structure of confined DNA, the high resistance to bending and the phase ...
Arsuaga, Javier +3 more
core
Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site
Nature Communications, 2016 The host cell factor cyclophilin A (CypA) interacts directly with the HIV-1 capsid and regulates viral infectivity. Although the crystal structure of CypA in complex with the N-terminal domain of the HIV-1 capsid protein (CA) has been known for nearly ...
Chuang Liu +17 more
semanticscholar +1 more source
Modeling capsid self-assembly: Design and analysis
, 2010 A series of simulations aimed at elucidating the self-assembly dynamics of spherical virus capsids is described. This little-understood phenomenon is a fascinating example of the complex processes that occur in the simplest of organisms.
Rapaport, D. C.
core +1 more source
Coarse-grained simulation reveals key features of HIV-1 capsid self-assembly
Nature Communications, 2016 The maturation of HIV-1 viral particles is essential for viral infectivity. During maturation, many copies of the capsid protein (CA) self-assemble into a capsid shell to enclose the viral RNA.
John M. A. Grime +6 more
semanticscholar +1 more source
The Astrovirus Capsid: A Review
Viruses, 2017 Astroviruses are enterically transmitted viruses that cause infections in mammalian and avian species. Astroviruses are nonenveloped, icosahedral viruses comprised of a capsid protein shell and a positive-sense, single-stranded RNA genome.
C. Arias, R. DuBois
semanticscholar +1 more source
A minimal representation of the self-assembly of virus capsids
, 2013 Viruses are biological nanosystems with a capsid of protein-made capsomer units that encloses and protects the genetic material responsible for their replication.
Breton, J. +2 more
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance The mechanisms of how TRIM5α interferes with the integrity of the HIV-1 capsid to restrict HIV-1 infectivity remain poorly understood. We examined, at atomic resolution, the interactions with TRIM5α in the assembled capsid and the dynamics ...
Caitlin M. Quinn +8 more
semanticscholar +1 more source