Results 71 to 80 of about 71,965 (172)

DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. [PDF]

, 2019
Assembly of Kaposi's sarcoma-associated herpesvirus (KSHV) begins at a bacteriophage-like portal complex that nucleates formation of an icosahedral capsid with capsid-associated tegument complexes (CATCs) and facilitates translocation of an ∼150-kb dsDNA
Bi, Guo-Qiang, Dai, Xinghong, Gong, Danyang, Jih, Jonathan, Liu, Yun-Tao, Sun, Ren, Zhou, Z Hong   +6 more
core  

Structural and Biochemical Characterization of a Widespread Enterobacterial Peroxidase Encapsulin

Advanced Science, EarlyView.
Encapsulins are self‐assembling bacterial protein compartments loaded with cargo enzymes. The most abundant encapsulin cargo class are Dye‐decolorizing Peroxidases (DyPs). In this study, we structurally and biochemically characterize a DyP encapsulin found in many enterobacteria.
Natalia C. Ubilla‐Rodriguez, Michael P. Andreas, Tobias W. Giessen   +2 more
wiley   +1 more source

Mechanisms of viral capsid assembly around a polymer [PDF]

, 2009
Capsids of many viruses assemble around nucleic acids or other polymers. Understanding how the properties of the packaged polymer affect the assembly process could promote biomedical efforts to prevent viral assembly or nanomaterials applications that ...
Aleksandr Kivenson, Angelescu, Angelescu, Angelescu, Aubouy, Bancroft, Belyi, Carmesin, Ceres, Conway, D'Souza, de Gennes, Devkota, Dixit, Elrad, Endres, Forrey, Fox, Grayson, Hagan, Hagan, Hagan, Hagan, Hariharan, Harvey, Hicks, Hu, Hu, Hu, Jack, Jiang, Johnson, Johnson, Johnston, Jouvenet, Jouvenet, Kegel, Krol, Lee, Licata, McPherson, Michael F. Hagan, Natarajan, Nguyen, Nguyen, Rapaport, Rosenbluth, Rudnick, Sakaue, Shaffer, Siber, Sikkema, Sorger, Stockley, Sun, Tihova, Toropova, Valegârd, van der Schoot, Whitelam, Whitelam, Whitesides, Wilber, Wilber, Yoffe, Zandi, Zhang, Zlotnick   +67 more
core   +3 more sources

Virome and Experimental Analysis Reveal Tryptophan‐Like Dissolved Organic Matter Contributes to the Persistence of Plant Viruses in River Water

Advanced Science, EarlyView.
Tryptophan‐like dissolved organic matter (Try‐like DOM), a key component of organic matter in river ecosystems, demonstrates significant protective effects against plant viruses. The protective mechanism operates via a “swimming firewall” mode, whereby free Try‐like DOM attenuates ultraviolet (UV) radiation and scavenges reactive oxygen species ...
Yujie Wang, Ming Chen, Liu Yang, Jun Ma, Jian Tang, Shengjun Wu, Chi He, J. Paul Chen   +7 more
wiley   +1 more source

Atomic model of the papillomavirus capsid [PDF]

The EMBO Journal, 2002
Papillomaviruses propagate in differentiating skin cells, and certain types are responsible for the onset of cervical cancer. We have combined image reconstructions from electron cryomicroscopy (cryoEM) of bovine papillomavirus at 9 A resolution with coordinates from the crystal structure of small virus-like particles of the human papillomavirus type ...
Yorgo Modis, Stephen C. Harrison, Benes L. Trus   +2 more
openaire   +2 more sources

How simple can a model of an empty viral capsid be? Charge distributions in viral capsids

, 2012
We investigate and quantify salient features of the charge distributions on viral capsids. Our analysis combines the experimentally determined capsid geometry with simple models for ionization of amino acids, thus yielding the detailed description of ...
A Lošdorfer Božič, A Šiber, A Šiber, A Šiber, A Šiber, A Šiber, Antonio Šiber, Anže Lošdorfer Božič, B Michen, CE Felder, CJ Marzec, CL Ting, DG Isom, DG Isom, J Bernal, J Langlet, JD Jackson, K Iwasaki, M Carrillo-Tripp, MR Gunner, P Ni, P Pfeiffer, P Prinsen, R Zandi, R Zandi, Rudolf Podgornik, RV Mannige, S Karlin, T Hu, The UniProt Consortium, TS Baker, VA Belyi, VA Parsegian, VB Chen, W Humphrey, WH Roos, WK Kegel, WK Kegel   +37 more
core   +1 more source

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source

Viral self-assembly as a thermodynamic process [PDF]

, 2003
The protein shells, or capsids, of all sphere-like viruses adopt icosahedral symmetry. In the present paper we propose a statistical thermodynamic model for viral self-assembly.
Bruinsma, Robijn F., Gelbart, William M., Reguera, David, Rudnick, Joseph, Zandi, Roya   +4 more
core   +3 more sources

DDX3 Regulates the Cap‐Independent Translation of the Japanese Encephalitis Virus via Its Interactions with PABP1 and the Untranslated Regions of the Viral Genome

Advanced Science, EarlyView.
Japanese encephalitis virus (JEV) employs a cap‐independent (CI) translation strategy to evade host translational shutoff. During the shut‐off of host cellular canonical translation, DEAD‐box protein 3 (DDX3) bind to JEV UTRs to establish a closed‐loop architecture, and its interaction with poly(A)‐binding protein 1 (PABP1) to form DDX3/PABP1/eIF4G ...
Chenxi Li, Linjie Zhang, Chenyang Tang, Xuan Chen, Jing Shi, Qingyu Li, Xue Jiao, Jinyao Guo, Bin Wang, Kefan Bu, Abdul Wahaab, Yuguo Yuan, Ming‐an Sun, Yanhua Li   +13 more
wiley   +1 more source

Impact of Virus‐Mediated Modifications in Bacterial Communities on the Accumulation of Soil Organic Carbon

Advanced Science, EarlyView.
This study illustrates the impact of viruses on carbon cycling in soils with different availabilities of carbon. In conditions of low carbon availability, viruses adopt a lysogenic lifestyle, integrate into the host genomes and facilitate the degradation of carbon.
Mingfeng Liu, Guixiang Zhou, Congzhi Zhang, Lin Chen, Donghao Ma, Lijun Zhang, Chunhua Jia, Ling Ma, Jiabao Zhang   +8 more
wiley   +1 more source