Cell Proliferation, EarlyView.AAV's widespread application is currently confronting critical challenges. This study established a systematic framework of ‘natural discovery–evolutionary analysis–functional optimization’, providing a new paradigm for the development of next‐generation AAV vectors with clinical‐grade tissue specificity, low immunogenicity, and cross‐species ...
Liyu Zhu +11 more
wiley +1 more source
Boosting the Separation of Adeno-Associated Virus Capsid Proteins by Liquid Chromatography and Capillary Electrophoresis Approaches. [PDF]
Int J Mol Sci, 2023 Aebischer MK +8 more
europepmc +1 more source
A novel kirkovirus may be associated with equine gastrointestinal disease
Equine Veterinary Journal, EarlyView.Abstract Background Many cases of equine enterocolitis are suspected to be infectious in nature, but no pathogen is identified in many cases. Objectives Perform next‐generation sequencing on faeces collected from cases of equine enterocolitis for the presence of novel viruses and determine if an identified novel virus is associated with cases of equine
Lillian M. B. Haywood +3 more
wiley +1 more source
Development of an icIEF assay for monitoring AAV capsid proteins and application to gene therapy products. [PDF]
Mol Ther Methods Clin Dev, 2023 He XZ +12 more
europepmc +1 more source
The Major Structural Protein of African Swine Fever Virus, p73, Is Packaged into Large Structures, Indicative of Viral Capsid or Matrix Precursors, on the Endoplasmic Reticulum [PDF]
, 1998 Christian Cobbold, Thomas Wileman
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Fish and Fisheries, EarlyView.Bacteriophage therapy is characterised by numerous advantages, facilitating its diverse aquaculture application and efficacy as an antibiotic alternative mitigating the spread of antimicrobial‐resistant pathogens. Contributing to the modern reappraisal of the aquaculture application of bacteriophage therapy, challenges impeding its widespread ...
Louise James +4 more
wiley +1 more source
Critical Residues Involved in the Coassembly of L1 and L2 Capsid Proteins of Human Papillomavirus 16. [PDF]
J Virol, 2023 Chen J +20 more
europepmc +1 more source
Expression and Characterization of Capsid Proteins Derived from GII.17 and GII.7 Noroviruses
, 2016 Xin Wan, Wenhui Wang
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RB1 inactivation in cutaneous carcinomas
Histopathology, EarlyView.Among skin carcinomas, recurrent RB1 inactivation is observed in Merkel cell carcinoma, in a subset of squamous cell carcinoma with bowenoid morphology, in sebaceous carcinoma and in the recently described Wnt/beta‐catenin rosette‐forming carcinoma.
Tiffany Liv +8 more
wiley +1 more source
Journal of Oral Pathology &Medicine, EarlyView.ABSTRACT Background Human papillomavirus (HPV)‐16 is the most commonly found HPV‐type in HPV‐induced oropharyngeal squamous cell carcinomas (OPSCC). The serological response to HPV oncoproteins could be a way to detect HPV‐driven OPSCC early. A rapid test for the detection of HPV16 L1 antibodies in blood was developed in 2015 (PrevoCheck).
Charlotte S. Schouten +4 more
wiley +1 more source