Results 161 to 170 of about 5,586,089 (360)

Anti‐Pseudomonas Aeruginosa Bacteriophage Loaded Electrospun Fibers for Antibacterial Wound Dressings

open access: yesMacromolecular Rapid Communications, EarlyView.
Multidrug resistant Pseudomonas (P.) aeruginosa is detected in many infected wounds and is challenging to treat with antibiotics. As an alternative, this work incorporates anti‐P. aeruginosa Neko phages into electrospun fibres to explore their potential for treating infected wounds.
Tian Ju   +7 more
wiley   +1 more source

The Hsp90β Isoform: An Attractive Target for Drug Development

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury   +2 more
wiley   +1 more source

Switchable Conformation in Protein Subunits: Unveiling Assembly Dynamics of Icosahedral Viruses [PDF]

open access: yesarXiv
The packaging of genetic material within a protein shell, called the capsid, marks a pivotal step in the life cycle of numerous single-stranded RNA viruses. Understanding how hundreds, or even thousands, of proteins assemble around the genome to form highly symmetrical structures remains an unresolved puzzle. In this paper, we design novel subunits and
arxiv  

The Antiviral Activity of Polyphenols

open access: yesMolecular Nutrition &Food Research, EarlyView.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard   +5 more
wiley   +1 more source

Occurrence and integrated control of major rice diseases in China

open access: yesNew Plant Protection, EarlyView.
Rice is constantly under threat from a variety of pathogens. This review highlights the major diseases affecting rice in China, including three fungal diseases, two bacterial diseases, two viral diseases, and one nematode. The review also proposes future directions for an integrated approach to control these significant rice diseases.
Ruyi Wang   +13 more
wiley   +1 more source

Multiple origins of viral capsid proteins from cellular ancestors

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
M. Krupovic, E. Koonin
semanticscholar   +1 more source

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

open access: yesPediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao   +6 more
wiley   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux   +6 more
wiley   +1 more source

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