Results 251 to 260 of about 1,705,592 (288)

Capsid structure of phage SPO1 reveals novel minor capsid proteins and insights into capsid stabilization

Structure
SPO1-related bacteriophages are promising candidates for phage therapy. We present the 3.0 Å cryo-electron microscopy (cryo-EM) structure of the SPO1 capsid with a triangulation number T = 16, enabling the construction of an atomic model comprising the major capsid protein and three types of minor capsid proteins: gp29.2, gp2.7, and gp36.3. These minor
Xinyue, Zhao, Aohan, Wang, Yueting, Wang, Yue, Kang, Qianqian, Shao, Lin, Li, Yaqi, Zheng, Hongli, Hu, Xiangyun, Li, Hongling, Fan, Can, Cai, Bing, Liu, Qianglin, Fang   +12 more
exaly   +3 more sources

Endocytosis of adenovirus and adenovirus capsid proteins

Advanced Drug Delivery Reviews, 2003
Key proteins of the icosahedral-shaped adenovirus (Ad) capsid mediate infection, and interact with cellular proteins to coordinate stepwise events of cell entry that produce successful gene transfer. Infection is mediated predominantly by the penton and fiber capsid proteins. The fiber initiates cell binding while the penton binds integrin coreceptors,
Lali Medina-Kauwe
exaly   +3 more sources

Papillomavirus capsid proteins mutually impact structure [PDF]

Virology, 2011
We studied a panel of mutant viruses containing wild-type and chimeric capsid HPV16 and HPV18 proteins. The mutant capsid protein expression, genome amplification, and episomal maintenance were comparable with the wild-type virus.
Craig Meyers, Neil Christensen, Michael J Conway   +2 more
exaly   +2 more sources

A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability [PDF]

Structure, 2023
Janne Juhani Ravantti, Simon White
exaly   +2 more sources

Maturation of poliovirus capsid proteins

Virology, 1992
The primary functions of viral capsids are (a) to protect the encapsidated nucleic acids from degradation, (b) to interact with specific cellular receptors on susceptible host cells in a manner that results in internalization of the genome, (c) to selectively package the newly synthesized genome, and (d) to facilitate its eventual exit.
C U, Hellen, E, Wimmer
openaire   +2 more sources

Formation of empty B19 parvovirus capsids by the truncated minor capsid protein

Journal of Virology, 1994
We previously reported that empty capsids of B19 parvovirus were formed by the major capsid protein (VP2) alone expressed in a baculovirus system, but the minor capsid protein (VP1), longer by 227 amino acids, alone did not form empty capsids. We report here further investigations of the constraints on capsid formation by truncated versions of VP1 ...
S, Wong, M, Momoeda, A, Field, S, Kajigaya, N S, Young   +4 more
openaire   +2 more sources

Modifying Filamentous Phage Capsid: Limits in the Size of the Major Capsid Protein

Journal of Molecular Biology, 1995
Ff filamentous phages are long thin cylindrical structures that infect bacteria displaying the F pilus and replicate without lysing the host. These structures are exploited to display peptides by fusing them to the amino terminus of either the bacterial receptor protein (pIII) or the major coat protein (pVIII).
G, Iannolo, O, Minenkova, R, Petruzzelli, G, Cesareni   +3 more
openaire   +2 more sources

Role of Capsid Proteins

2008
Coat proteins (CPs) of all plant viruses have an early function in disassembly of parental virus and a late function in assembly of progeny virus. Depending on the virus, however, CPs may play a role in many steps of the infection cycle in between these early and late functions.
openaire   +2 more sources

A minor capsid protein P30 is essential for bacteriophage PRD1 capsid assembly

Journal of Molecular Biology, 2001
Bacteriophage PRD1 is a double-stranded DNA virus infecting Gram-negative hosts. It has a membrane component located in the interior of the isometric capsid. In addition to the major capsid protein P3, the capsid contains a 9 kDa protein P30. Protein P30 is proposed to be located between the adjacent facets of the icosahedral capsid and is required for
P S, Rydman, J K, Bamford, D H, Bamford
openaire   +2 more sources

Capsid Protein-Encoding Genes of Hamster Polyomavirus and Properties of the Viral Capsid

Virus Genes, 1999
On the basis of its genome organization the hamster polyomavirus (HaPV) is closely related to the murine polyomavirus Py. But HaPV infection, in contrast to Py infection, gives rise to two different tumor types; depending on the hamster strain used for infection, HaPV induces either epitheliomas or lymphomas.
H, Siray, M, Ozel, B, Jandrig, T, Voronkova, W, Jia, R, Zocher, W, Arnold, S, Scherneck, D H, Krüger, R, Ulrich   +9 more
openaire   +2 more sources