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CD70-targeted iPSC-derived CAR-NK cells display potent function against tumors and alloreactive TÂ cells. [PDF]
Wang L +25 more
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Correction: CAR-NK cells with dual targeting of PD-L1 and MICA/B in lung cancer tumor models. [PDF]
Zhi L +8 more
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Engineered CRO-CD7 CAR-NK cells derived from pluripotent stem cells avoid fratricide and efficiently suppress human T-cell malignancies. [PDF]
Lin Y +28 more
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Nanobody-based CAR NK cells for possible immunotherapy of MICA+ tumors. [PDF]
Verhaar ER +4 more
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CAR-NK cells: a promising cellular immunotherapy in lymphoma
Expert Opinion on Biological Therapy, 2022New methods in cancer immunotherapy, such as chimeric antigen receptor (CAR)-T cells, have shown promising results in destroying malignant cells. However, limitations and side effects of CAR-T cell therapy, such as graft-versus-host disease (GVHD), neurotoxicity, and cytokine release syndrome, have motivated researchers to investigate safer alternative
Shaghayegh, Khanmohammadi, Nima, Rezaei
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Nonviral technologies can pave the way for CAR-NK cell therapy
Journal of Leukocyte Biology, 2023Abstract Natural killer cells are a promising platform for cancer immunotherapy. Natural killer cells have high intrinsic killing capability, and the insertion of a chimeric antigen receptor can further enhance their antitumor potential. In first-in-human trials, chimeric antigen receptor–natural killer cells demonstrated strong clinical
Tobias Bexte +2 more
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