Results 11 to 20 of about 382,335 (262)
Conventional CARs versus modular CARs [PDF]
Cancer Immunology, Immunotherapy, 2019 Abstract The clinical application of immune effector cells genetically modified to express chimeric antigen receptors (CARs) has shown impressive results including complete remissions of certain malignant hematological diseases. However, their application can also cause severe side effects such as cytokine release syndrome (CRS) or tumor ...
Feldmann, A. +5 more
openaire +2 more sources
CD28z CARs and Armored CARs [PDF]
The Cancer Journal, 2014 CD19-targeted chimeric antigen receptor (CAR) T cells are currently being tested in the clinic with very promising outcomes. However, limitations to CAR T cell therapy exist. These include lack of efficacy against some tumors, specific targeting of tumor cells without affecting normal tissue and retaining activity within the suppressive tumor ...
Hollie J, Pegram +2 more
openaire +2 more sources
Revista Iberoamericana de Automática e Informática Industrial RIAI, 2023 Este artículo presenta el diseño y desarrollo de una arquitectura electrónica bioinspirada en el sistema motor humano para sistemas de asistencia a la locomoción, como es en el caso de exoesqueletos de asistencia o de rehabilitación.
Gabriel Delgado-Oleas +4 more
doaj +1 more source
CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy
Journal of Experimental & Clinical Cancer Research, 2022 AbstractAdoptive cell therapy with chimeric antigen receptor (CAR) immunotherapy has made tremendous progress with five CAR T therapies approved by the US Food and Drug Administration for hematological malignancies. However, CAR immunotherapy in solid tumors lags significantly behind.
Kevin Pan +5 more
openaire +3 more sources
Nutrición Hospitalaria, 2014 Introduction: The discovery of vitamin D muscle receptors in the last few years suggested a significant role in muscle tissue, pointing out athletes as a special group. Specific data are scarce.
Jara Valtueña +4 more
doaj +1 more source
ANALYSIS OF ENERGY SAVING AND ENERGY EFFICIENCY ISSUES DURING OPERATION OF THE METRO ROLLING STOCK
Nauka ta progres transportu, 2016 Purpose.Nowadays a problem of significant power consumption of the rolling stock during its operation is a current issue. In connection with staged electricity rates increase further development of the rail electric transport, including metro rolling ...
A. V. Donchenko +4 more
doaj +1 more source
Nauka ta progres transportu, 2017 Purpose. The analysis of the existing studies showed that the increasing of energy efficiency of metro rolling stock becomes especially important and requires timely solutions.
A. O. Sulym +4 more
doaj +1 more source
Robot Transparency and Anthropomorphic Attribute Effects on Human–Robot Interactions
Sensors, 2021 Anthropomorphic robots need to maintain effective and emotive communication with humans as automotive agents to establish and maintain effective human–robot performances and positive human experiences. Previous research has shown that the characteristics
Jianmin Wang +6 more
doaj +1 more source
Вестник Научно-исследовательского института железнодорожного транспорта, 2021 Investigations of the frequency of bending vibrations of the car bodies of 61-4440 model range, which includes compartment cars, staff cars, non-compartment cars, coach cars, restaurant cars and others, are described. The bodies of all cars of this model
A. N. Skachkov +4 more
doaj +1 more source
ROMERIN: Organismo robótico escalador basado en patas modulares con ventosas activas
Revista Iberoamericana de Automática e Informática Industrial RIAI, 2022 Este artículo presenta el robot ROMERIN, un organismo robótico modularmente compuesto por patas que utilizan ventosas activas como sistema de adhesión al entorno, y cuyo objetivo es la inspección de infraestructuras mediante la escalada.
Carlos Prados +3 more
doaj +1 more source