Specificity of carbachol in the elicitation of drinking [PDF]
Two studies were reported in which rats with hypothalamic cannulae were injected with carbachol. All animals exhibited drinking following injection. In the first study, this was demonstrated both prior to and following a series of test sessions, and in the second study, at the end only.
Larry R. Beideman, Robert Goldstein
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Time‐dependent bladder activity changes in streptozotocin‐induced female diabetic rats [PDF]
This study aimed to investigate the long‐term physiological and morphological changes in the bladders of diabetic rats. Sixty‐nine female Sprague–Dawley rats were divided into a control and six diabetic (3 days and 2, 4, 8, 12, and 24 weeks after ...
Keiichiro Izumi+7 more
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Comparisons of urinary bladder responses to common antimuscarinics reveals unique effects of darifenacin [PDF]
IntroductionAntimuscarinics are the first-line pharmaceutical treatment for overactive bladder (OAB). However, some literature suggests that responses to these antimuscarinics can influence a variety of non-muscarinic receptors.
Vineesha Veer+2 more
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Local carbachol application induces oral microvascular recruitment and improves gastric tissue oxygenation during hemorrhagic shock in dogs [PDF]
IntroductionHemorrhagic shock is characterized by derangements of the gastrointestinal microcirculation. Topical therapy with nitroglycerine or iloprost improves gastric tissue oxygenation but not regional perfusion, probably due to precapillary ...
Stefan Hof+9 more
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Changes in Anxiety-Related Behaviors, Voiding Patterns, and Urinary Bladder Contractile Properties in Male Mice Exposed to Water Avoidance Stress for 1 Day and 28 Days [PDF]
Repeated water avoidance stress (WAS) for 10 days is a common rodent model to mimic the effect of chronic psychological stress on urinary bladder dysfunction.
Sarunnuch Sattayachiti+4 more
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Unique responses of the fixed stoichiometric TRPC1–TRPC5 concatemer to G proteins [PDF]
Transient receptor potential canonical (TRPC)5 channel is a non-selective cation channel that plays a significant role in membrane depolarization and calcium influx. TRPC5 not only forms homotetramers itself but also heterotetramers with TRPC1.
Hana Kang, Insuk So, Insuk So
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Inhibition of carbachol-induced inositol phosphate accumulation in the embryonic retina promoted by kainate and veratridine [PDF]
In the present study, we report that low concentrations of the glutamate ionotropic agonist kainate decreased the turnover of [3H]-phosphoinositides ([3H]-InsPs) induced by muscarinic receptors in the chick embryonic retina.
G. Sanches, A.L.M. Ventura
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Mechanisms of carbachol oscillations
Netoff Theoden I+2 more
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Dysphania ambrosioides (L.) Mosyakin and Clemants is an annual or ephemeral perennial herb used traditionally in the Mediterranean region in folk medicine to treat various illnesses, including those related to the digestive system.
Fahd Kandsi+9 more
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Recent studies have implicated impaired Parvalbumin Fast-Spiking Interneuron (PVIN) function as a precipitating factor underlying abnormalities in network synchrony, oscillatory rhythms, and cognition associated with Alzheimer’s disease (AD).
Connie A. Mackenzie-Gray Scott+9 more
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