Specificity of carbachol in the elicitation of drinking [PDF]
Two studies were reported in which rats with hypothalamic cannulae were injected with carbachol. All animals exhibited drinking following injection. In the first study, this was demonstrated both prior to and following a series of test sessions, and in the second study, at the end only.
Larry R. Beideman, Robert E. Goldstein
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Time‐dependent bladder activity changes in streptozotocin‐induced female diabetic rats [PDF]
This study aimed to investigate the long‐term physiological and morphological changes in the bladders of diabetic rats. Sixty‐nine female Sprague–Dawley rats were divided into a control and six diabetic (3 days and 2, 4, 8, 12, and 24 weeks after ...
Keiichiro Izumi+7 more
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Comparisons of urinary bladder responses to common antimuscarinics reveals unique effects of darifenacin [PDF]
IntroductionAntimuscarinics are the first-line pharmaceutical treatment for overactive bladder (OAB). However, some literature suggests that responses to these antimuscarinics can influence a variety of non-muscarinic receptors.
Vineesha Veer+2 more
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Pairing the cholinergic agonist carbachol with patterned Schaffer collateral stimulation initiates protein synthesis in hippocampal CA1 pyramidal cell dendrites via a muscarinic, NMDA-dependent mechanism [PDF]
Effects of afferent stimulation on local synthesis of protein in CA1 pyramidal cell dendrites were studied using light microscope autoradiography. Tissue was fixed with paraformaldehyde immediately after 3 min exposure to 3H-leucine in order to trap 3H ...
Sherry L. Feig, Peter Lipton
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Inhibition of carbachol-induced inositol phosphate accumulation in the embryonic retina promoted by kainate and veratridine [PDF]
In the present study, we report that low concentrations of the glutamate ionotropic agonist kainate decreased the turnover of [3H]-phosphoinositides ([3H]-InsPs) induced by muscarinic receptors in the chick embryonic retina.
G. Sanches, A.L.M. Ventura
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Mechanism of chloride secretion induced by carbachol in a colonic epithelial cell line. [PDF]
K. Dharmsathaphorn, Stephen J. Pandol
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Unique responses of the fixed stoichiometric TRPC1–TRPC5 concatemer to G proteins [PDF]
Transient receptor potential canonical (TRPC)5 channel is a non-selective cation channel that plays a significant role in membrane depolarization and calcium influx. TRPC5 not only forms homotetramers itself but also heterotetramers with TRPC1.
Hana Kang, Insuk So, Insuk So
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Mechanisms of carbachol oscillations
Netoff Theoden I+2 more
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Glucose and carbachol generate 1,2-diacylglycerols by different mechanisms in pancreatic islets. [PDF]
Bettina Peter-Riesch+3 more
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GTP‐binding protein involvement in membrane currents evoked by carbachol and histamine in guinea‐pig ileal muscle. [PDF]
S. Komori+3 more
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