Results 11 to 20 of about 43,661 (255)

In vitro study of spontaneous motility and cholinergic responses in the human Hirschsprung's disease colon [PDF]

open access: yesFrontiers in Pediatrics
BackgroundThe current standard treatment of Hirschsprung's disease (HD) involves complete resection of the aganglionic intestinal segment with routine rectal irrigation pre- and postoperatively.
Felix Schulze   +7 more
doaj   +2 more sources

Carbachol-mediated pigment granule dispersion in retinal pigment epithelium requires Ca2+ and calcineurin

open access: yesBMC Cell Biology, 2007
Background Inside bluegill (Lepomis macrochirus) retinal pigment epithelial cells, pigment granules move in response to extracellular signals. During the process of aggregation, pigment motility is directed toward the cell nucleus; in dispersion, pigment
García Dana M, Johnson Adam S
doaj   +2 more sources

Time‐dependent bladder activity changes in streptozotocin‐induced female diabetic rats [PDF]

open access: yesPhysiological Reports
This study aimed to investigate the long‐term physiological and morphological changes in the bladders of diabetic rats. Sixty‐nine female Sprague–Dawley rats were divided into a control and six diabetic (3 days and 2, 4, 8, 12, and 24 weeks after ...
Keiichiro Izumi   +7 more
doaj   +2 more sources

Comparisons of urinary bladder responses to common antimuscarinics reveals unique effects of darifenacin [PDF]

open access: yesFrontiers in Physiology
IntroductionAntimuscarinics are the first-line pharmaceutical treatment for overactive bladder (OAB). However, some literature suggests that responses to these antimuscarinics can influence a variety of non-muscarinic receptors.
Vineesha Veer   +2 more
doaj   +2 more sources

Vasoactivity of Rac GTPase, Cytohesin and Kinase Inhibitors in Renal Interlobar and Coronary Arteries Reveals Shared and Distinct Patterns of Inhibitory Effects in Vascular and Prostate Smooth Muscle Contraction. [PDF]

open access: yesPharmacol Res Perspect
ABSTRACT Inhibition of vasocontraction accounts for side effects in treating voiding symptoms in benign prostatic hyperplasia (BPH). We examined the vasoactivity of compounds previously showing inhibition of prostate smooth muscle contraction. Contractions of porcine renal interlobar and coronary arteries were induced by agonists or electric field ...
Liu G   +6 more
europepmc   +2 more sources

Mechanisms of carbachol oscillations

open access: yesBMC Neuroscience, 2007
Netoff Theoden I   +2 more
doaj   +3 more sources

Water Drinking Behavior Associated with Aversive Arousal in Rats: An Integrative Approach

open access: yesBrain Sciences, 2022
Cholinergic muscarinic stimulation of vast areas of the limbic brain induced a well-documented polydipsia in laboratory rats. This excessive water-drinking behavior has not received any convincing biological and physiological interpretation for the last ...
Stefan M. Brudzynski
doaj   +1 more source

KV7 Channel Expression and Function Within Rat Mesenteric Endothelial Cells

open access: yesFrontiers in Physiology, 2020
Background and Purpose: Arterial diameter is dictated by the contractile state of the vascular smooth muscle cells (VSMCs), which is modulated by direct and indirect inputs from endothelial cells (ECs).
Samuel N. Baldwin   +4 more
doaj   +1 more source

Phytochemical Analysis, Antispasmodic, Myorelaxant, and Antioxidant Effect of Dysphania ambrosioides (L.) Mosyakin and Clemants Flower Hydroethanolic Extracts and Its Chloroform and Ethyl Acetate Fractions

open access: yesMolecules, 2021
Dysphania ambrosioides (L.) Mosyakin and Clemants is an annual or ephemeral perennial herb used traditionally in the Mediterranean region in folk medicine to treat various illnesses, including those related to the digestive system.
Fahd Kandsi   +9 more
doaj   +1 more source

A Cholinergic Synaptically Triggered Event Participates in the Generation of Persistent Activity Necessary for Eye Fixation [PDF]

open access: yes, 2004
An exciting topic regarding integrative properties of the nervous system is how transient motor commands or brief sensory stimuli are able to evoke persistent neuronal changes, mainly as a sustained, tonic action potential firing.
Alvarado, Juan Carlos   +5 more
core   +4 more sources

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