Results 21 to 30 of about 16,333 (208)

Carbachol and Nicotine in Prefrontal Cortex Have Differential Effects on Sleep-Wake States

Frontiers in Neuroscience, 2020
The role of the brainstem cholinergic system in the regulation of sleep-wake states has been studied extensively but relatively little is known about the role of cholinergic mechanisms in prefrontal cortex in the regulation of sleep-wake states.
Anjum Parkar, Donald C. Fedrigon, Farah Alam, Giancarlo Vanini, Giancarlo Vanini, Giancarlo Vanini, George A. Mashour, George A. Mashour, George A. Mashour, Dinesh Pal, Dinesh Pal, Dinesh Pal   +11 more
doaj   +1 more source

Regulation of CCK-induced ERK1/2 activation by PKC epsilon in rat pancreatic acinar cells

AIMS Molecular Science, 2017
The extracellular signal-regulated kinase ERK1/2 is activated in pancreatic acinar cells by cholecystokinin (CCK) and other secretagogues with this activation mediated primarily by protein kinase C (PKC).
Chenwei Li, John A. Williams
doaj   +1 more source

The Transition Between Slow-Wave Sleep and REM Sleep Constitutes an Independent Sleep Stage Organized by Cholinergic Mechanisms in the Rostrodorsal Pontine Tegmentum

Frontiers in Neuroscience, 2019
There is little information on either the transition state occurring between slow-wave sleep (SWS) and rapid eye movement (REM) sleep, as well as about its neurobiological bases.
Carlos Carrera-Cañas, Miguel Garzón, Isabel de Andrés   +2 more
doaj   +1 more source

TRPV4 Complexes With the Na+/Ca2+ Exchanger and IP3 Receptor 1 to Regulate Local Intracellular Calcium and Tracheal Tension in Mice

Frontiers in Physiology, 2019
Intracellular Ca2+ is critical for regulating airway smooth muscle (ASM) tension. A rapid rise in the intracellular Ca2+ concentration ([Ca2+]i) of ASM cells is crucial for modulating the intensity and length of the ASM contraction.
Jie Zhang, Jie Zhang, Yuan Wei, Suwen Bai, Shenggang Ding, Huiwen Gao, Sheng Yin, Sheng Yin, Shuo Chen, Jinsen Lu, Haoran Wang, Yonggang Shen, Bing Shen, Juan Du   +13 more
doaj   +1 more source

Autoantibodies against muscarinic receptors in breast cancer: their role in tumor angiogenesis. [PDF]

PLoS ONE, 2013
The presence of autoantibodies in cancer has become relevant in recent years. We demonstrated that autoantibodies purified from the sera of breast cancer patients activate muscarinic acetylcholine receptors in tumor cells.
María Gabriela Lombardi, María Pía Negroni, Laura Tatiana Pelegrina, María Ester Castro, Gabriel L Fiszman, María Eugenia Azar, Carlos Cresta Morgado, María Elena Sales   +7 more
doaj   +1 more source

Functional evidence that the central renin-angiotensin system plays a role in the pressor response induced by central injection of carbachol

Brazilian Journal of Medical and Biological Research, 1997
We investigated the effects of losartan, an AT1-receptor blocker, and ramipril, a converting enzyme inhibitor, on the pressor response induced by angiotensin II (ANG II) and carbachol (a cholinergic receptor agonist).
W.A. Saad, A.C. Luiz, L.A.A. Camargo, J.E.N. Silveira, S. Fóglia, J.V. Menani, William A. Saad   +6 more
doaj   +1 more source

Case report: Acute unintentional carbachol intoxication [PDF]

Critical Care, 2006
Abstract Introduction Intoxications with carbachol, a muscarinic cholinergic receptor agonist are rare. We report an interesting case investigating a (near) fatal poisoning. Methods The son of an 84-year-old male discovered a newspaper ...
Schulz, Martin, Graefe, Thomas, Stuby, Klaus, Andresen, Hilke, Kupfermann, Nikolai, Schmoldt, Achim   +5 more
openaire   +5 more sources

Ecofriendly Long Life Nanocomposite Sensors for Determination of Carbachol in Presence of Choline: Application in Ophthalmic Solutions and Biological Fluids

Sensors, 2019
Several emerging nano scale forms of carbon are showing great promise in electrochemical sensing such as graphene and multi-walled carbon nanotubes (MWCNTs).
Eman A. Al-Harbi, Mona H. Abdelrahman, Amira M. El-Kosasy   +2 more
doaj   +1 more source

Curcuma longa extract exerts a myorelaxant effect on the ileum and colon in a mouse experimental colitis model, independent of the anti-inflammatory effect. [PDF]

PLoS ONE, 2012
BACKGROUND: Curcuma has long been used as an anti-inflammatory agent in inflammatory bowel disease. Since gastrointestinal motility is impaired in inflammatory states, the aim of this work was to evaluate if Curcuma Longa had any effect on intestinal ...
Rita Aldini, Roberta Budriesi, Giulia Roda, Matteo Micucci, Pierfranco Ioan, Antonia D'Errico-Grigioni, Alessandro Sartini, Elena Guidetti, Margherita Marocchi, Monica Cevenini, Francesca Rosini, Marco Montagnani, Alberto Chiarini, Giuseppe Mazzella   +13 more
doaj   +1 more source

Carbachol-mediated pigment granule dispersion in retinal pigment epithelium requires Ca²⁺ and calcineurin

BMC Cell Biology, 2007
Background Inside bluegill (Lepomis macrochirus) retinal pigment epithelial cells, pigment granules move in response to extracellular signals. During the process of aggregation, pigment motility is directed toward the cell nucleus; in dispersion, pigment
García Dana M, Johnson Adam S
doaj   +1 more source