Distinct agonist regulation of muscarinic acetylcholine M2-M3 heteromers and their corresponding homomers [PDF]
, 2015 Each subtype of the muscarinic receptor family of G protein-coupled receptors is activated by similar concentrations of the neurotransmitter acetylcholine or closely related synthetic analogs such as carbachol. However, pharmacological selectivity can be
Alvarez-Curto, Elisa +3 more
core +1 more source
Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. [PDF]
, 2019 There is an increasing prevalence of esophageal diseases but intact human tissue platforms to study esophageal function, disease mechanisms, and the interactions between cell types in situ are lacking.
Aceves, Seema S +12 more
core +3 more sources
Recovery of hippocampal functions and modulation of muscarinic response by electroacupuncture in young diabetic rats [PDF]
, 2017 The muscarinic receptor response to acetylcholine regulates the hippocampal-related learning, memory, neural plasticity and the production and processing of the pro-nerve growth factor (proNGF) by hippocampal cells.
Berretta, Erica +9 more
core +2 more sources
Molecules and Cells, 2009 We studied the effect of carbachol on pacemaker currents in cultured interstitial cells of Cajal (ICC) from the mouse small intestine by muscarinic stimulation using a whole cell patch clamp technique and Ca2+-imaging.
K. So +8 more
semanticscholar +1 more source
Reduction in jejunal fluid absorption in vivo through distension and cholinergic stimulation not attributable to enterocyte secretion [PDF]
, 2018 Jejunal fluid absorption in vivo was reduced by distension and by hydrostatic pressure and further declined on adding E. coli STa enterotoxin but no net fluid secretion was detected.
Graham, V. +8 more
core +1 more source
Sensors, 2019 Several emerging nano scale forms of carbon are showing great promise in electrochemical sensing such as graphene and multi-walled carbon nanotubes (MWCNTs).
Eman A. Al-Harbi +2 more
doaj +1 more source
Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties [PDF]
, 2011 Reduced NO levels due to the deficiency of tetrahydrobiopterin (BH4) contribute to impaired vasodilation in pulmonary hypertension Due to the chemically unstable nature of BH4 it was hypothesised that oxidatively stable analogues of BR, would be able to ...
Gibson, Colin +4 more
core +1 more source
Intracellular free sodium and potassium, post-carbachol hyperpolarization, and extracellular potassium-undershoot in rat sympathetic neurones [PDF]
, 1983 Double-barrelled ion-sensitive microelectrodes were used to record the free intracellular Na+- and K+-concentrations ([Na+]i, [K+]i) and to determine their relation to changes in membrane potential and extracellular K+ ([K+]e) in rat sympathetic ganglia.
Brown +15 more
core +1 more source
Autoantibodies against muscarinic receptors in breast cancer: their role in tumor angiogenesis. [PDF]
PLoS ONE, 2013 The presence of autoantibodies in cancer has become relevant in recent years. We demonstrated that autoantibodies purified from the sera of breast cancer patients activate muscarinic acetylcholine receptors in tumor cells.
María Gabriela Lombardi +7 more
doaj +1 more source