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Monitoring Carbapenem-Resistant Enterobacterales in the Environment to Assess the Spread in the Community

Antibiotics, 2022
The usefulness of wastewater-based epidemiology (WBE) was proven during the COVID-19 pandemic, and the role of environmental monitoring of emerging infectious diseases has been recognized. In this study, the prevalence of carbapenem-resistant Enterobacterales (CRE) in Japanese environmental samples was measured in the context of applying WBE to CRE.
Taro Urase
exaly   +4 more sources

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Characteristics of community-acquired carbapenem-resistant Enterobacterales

Journal of Antimicrobial Chemotherapy, 2022
AbstractBackgroundCommunity-acquired carbapenem-resistant Enterobacterales (CA-CRE) are an important threat.MethodsIn CRACKLE-2, we defined patients with CA-CRE as admitted from home, without pre-existing conditions, and a positive culture within 48 h of admission.
Rima Shrestha, Courtney L Luterbach, Weixiao Dai, Lauren Komarow, Michelle Earley, Gregory Weston, Erica Herc, Jesse T Jacob, Robert Salata, Darren Wong, Deverick Anderson, Kirsten B Rydell, Cesar A Arias, Liang Chen, David van Duin, Gregory Weston, Belinda Ostrowsky, Judith J Lok, Robert A Bonomo, T Nicholas Domitrovic, Kristine M Hujer, Andrea M Hujer, Susan D Rudin, Steven H Marshall, Robert A Salata, Federico Perez, Eric Cober, Sandra S Richter, Rebekka Arias, Carol Hill, Vance G Fowler, Deverick J Anderson, Jesse T Jacob, Minggui Wang, Liang Chen, Samit Desai, Barry N Kreiswirth, Claudia Manca, Jose R Mediavilla, Gopi Patel, W Charles Huskins, Robin Patel, Sara Revolinski, Glenn Wortmann, Robert C Kalayjian, Angela Kim, Julia Garcia-Diaz, Bettina C Fries, Brandon Eilertson, Jason C Gallagher, Michelle Earley, Scott Evans, Lauren Komarow, Omai B Garner, Henry F Chambers, John J Farrell, Lilian M Abbo, Keith S Kaye, Courtney Luterbach, David van Duin, Jennifer H Han, Yohei Doi, David L Paterson, Darren Wong, Cesar A Arias, Blake Hanson, An Dinh, Diana Panesso, William Shropshire, Truc T Tran, Ritu Banerjee, Sorabh Dhar, Michael J Satlin, Matthew Grant   +73 more
openaire   +2 more sources

Molecular Characterization of Carbapenem-Resistant Enterobacterales Collected in the United States

Microbial Drug Resistance, 2022
Carbapenem-resistant Enterobacterales (CRE) are a growing public health concern due to resistance to multiple antibiotics and potential to cause health care-associated infections with high mortality. Carbapenemase-producing CRE are of particular concern given that carbapenemase-encoding genes often are located on mobile genetic ...
Jesse Jacob, Alexander Kallen, Lucy Wilson   +2 more
exaly   +3 more sources

Clinical and genomic characterization of carbapenem-resistant Enterobacterales bloodstream infections in patients with hematologic malignancies [PDF]

Frontiers in Cellular and Infection Microbiology
BackgroundCarbapenem-resistant Enterobacterales (CRE) bloodstream infections (BSIs) pose a significant risk to patients with hematologic malignancies, yet the distinct features and outcomes of these infections are not thoroughly understood.MethodsThis ...
Jiangqing Huang
exaly   +2 more sources

Predictors of Resistance to Ceftazidime-Avibactam in Carbapenem-Resistant Enterobacterales

Infectious Diseases in Clinical Practice, 2022
Background Ceftazidime-avibactam (CAZ-AVI) is a safe and effective treatment option for carbapenem-resistant Enterobacterales (CRE). However, predictors of resistance to CAZ-AVI have not been well defined. Therefore, our study describes risk factors for resistance to CAZ-AVI in hospitalized patients with CRE infections.
Tae Eun Park, Eris Cani, Paul Kelly, Lendelle Raymond, Banibrata Roy, Cosmina Zeana, Anupama Menon   +6 more
openaire   +1 more source

The epidemiology of carbapenem-resistant Enterobacterales in a single center in Oman

International Journal of Infection Control, 2023
Background: Carbapenem-resistant Enterobacterales (CRE) are a global public health threat associated with significant morbidity and mortality. Objectives: The study aims to describe the epidemiology, microbiology and outcome of patients with CRE infection or colonization during an active surveillance program and to determine the risk factors for the ...
Ahmed AL Yarabi, Zaina AL Maskari, Amal AL Tai, Faryal Khamis, Eskild Petersen, Amina AL Jardani   +5 more
openaire   +1 more source

Carbapenem-resistant Enterobacterales (CRE): The storm is coming

Intensive and Critical Care Nursing, 2023
Zahar, Jean-Ralph, Blot, Stijn
openaire   +4 more sources

Reviewing novel treatment options for carbapenem-resistant Enterobacterales

Expert Review of Anti-infective Therapy
Carbapenem resistant Enterobacterales (CRE) are a major threat to global health and hospital-onset CRE infections have risen during the COVID-19 pandemic. Novel antimicrobials are now available for the treatment of CRE infections. There remains an urgent need for new antimicrobials for CRE, especially for those producing metallo-β-lactamases.This ...
Natalie A, Mackow, David, van Duin
openaire   +2 more sources

Carbapenem-resistant Enterobacterales in the USA

The Lancet Infectious Diseases, 2020
Sumanth, Gandra, Carey-Ann D, Burnham
openaire   +2 more sources