Results 41 to 50 of about 810,489 (200)

Molecular epidemiology and outcome of carbapenem-resistant Enterobacterales in Saudi Arabia

BMC Infectious Diseases, 2022
Abstract Background The burden of carbapenem resistance is not well studied in the Middle East. We aimed to describe the molecular epidemiology and outcome of carbapenem-resistant Enterobacterales (CRE) infections from several Saudi Arabian Centers.
Basem M. Alraddadi, Emily L. G. Heaphy, Yamama Aljishi, Waleed Ahmed, Khalid Eljaaly, Hanan H. Al-Turkistani, Abeer N. Alshukairi, Mohammed O. Qutub, Kholoud Alodini, Roaa Alosaimi, Waseem Hassan, Dalya Attalah, Rakan Alswaiel, Mohammed F. Saeedi, Mohammed A. Al-Hamzi, Lama K. Hefni, Reem S. Almaghrabi, Mushira Anani, Abdulhakeem Althaqafi   +18 more
openaire   +3 more sources

Poor outcomes in both infection and colonization with carbapenem-resistant Enterobacterales

Infection Control & Hospital Epidemiology, 2022
AbstractObjectives:To describe the epidemiology of patients with nonintestinal carbapenem-resistant Enterobacterales (CRE) colonization and to compare clinical outcomes of these patients to those with CRE infection.Design:A secondary analysis of Consortium on Resistance Against Carbapenems in Klebsiella and other Enterobacteriaceae 2 (CRACKLE-2), a ...
Jessica R. Howard-Anderson, Michelle Earley, Lauren Komarow, Lilian Abbo, Deverick J. Anderson, Jason C. Gallagher, Matthew Grant, Angela Kim, Robert A. Bonomo, David van Duin, L. Silvia Muñoz-Price, Jesse T. Jacob   +11 more
openaire   +2 more sources

Assessing Colistin Resistance by Phenotypic and Molecular Methods in Carbapenem-resistant Enterobacterales in a Tertiary Care Hospital in Pakistan

Infection and Drug Resistance, 2022
Warda Furqan, Sakhawat Ali, Javaid Usman, Faisal Hanif, Afnan Naeem, Amnah Nasrullah, Nadia Tayyab Department of Microbiology Army Medical College (National University of Medical Sciences), Rawalpindi, PakistanCorrespondence: Warda Furqan, House No.
Furqan W, Ali S, Usman J, Hanif F, Naeem A, Nasrullah A, Tayyab N   +6 more
doaj  

Colistin Resistance among Enterobacterales Isolates: Underlying Mechanisms and Alternative Treatment Options

Journal of Pure and Applied Microbiology, 2023
Global dissemination of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative bacteria (GNB) such as carbapenemase-producing Enterobacterales has resulted in reviving colistin as a final therapeutic alternative. Colistin resistance
Amal F. Makled, Sahar A.M. Ali, Ahmed B. Mahmoud, Marwa E. Eltoukhy, Reem M. Elkholy, Athar F. Lasheen, Asmaa Mohammed Elbrolosy   +6 more
doaj   +1 more source

Risk Factors for Carbapenem-Resistant Enterobacterales Clinical Treatment Failure

Microbiology Spectrum, 2023
This work compares carbapenem-resistant Enterobacterales (CRE) infections using patient, clinical, and treatment variables to understand which characteristics are associated with the highest risk of clinical failure.
Nicholas Rebold, Abdalhamid M. Lagnf, Sara Alosaimy, Dana J. Holger, Paige Witucki, Andrew Mannino, Michelle Dierker, Kristen Lucas, Ashlan J. Kunz Coyne, Amer El Ghali, Kaylee E. Caniff, Michael P. Veve, Michael J. Rybak   +12 more
openaire   +3 more sources

Carbapenem-Resistant Gram-Negative Bacilli Characterization in a Tertiary Care Center from El Bajio, Mexico

Antibiotics, 2023
Carbapenem-resistant Gram-negative bacilli (CR-GNB) are a major public health concern. We aimed to evaluate the prevalence of CR-GNB and the frequency of carbapenemase-encoding genes in a tertiary referral center from El Bajio, Mexico.
Jose Raul Nieto-Saucedo, Luis Esaú López-Jacome, Rafael Franco-Cendejas, Claudia Adriana Colín-Castro, Melissa Hernández-Duran, Luis Raúl Rivera-Garay, Karina Senyase Zamarripa-Martinez, Juan Luis Mosqueda-Gómez   +7 more
doaj   +1 more source

Early Years of Carbapenem-Resistant Enterobacterales Epidemic in Abu Dhabi

Antibiotics, 2022
Recent studies showed that the current endemic of carbapenem-resistant Enterobacterales (CRE) in the Emirate of Abu Dhabi is dominated by highly resistant Klebsiella pneumoniae clones ST14, ST231, and CC147, respectively. In the absence of continuous, molecular typing-based surveillance, it remained unknown whether they lately emerged and rapidly ...
Tibor Pál, Aqdas B. Butt, Akela Ghazawi, Jens Thomsen, Tahir A. Rizvi, Ágnes Sonnevend   +5 more
openaire   +3 more sources

Effect of Colistin, Fosfomycin and Meropenem/Vaborbactam on Carbapenem-Resistant Enterobacterales in Egypt: A Cross-Sectional Study

Infection and Drug Resistance, 2022
Raghdaa Shrief,1 Amira H El-Ashry,2 Rasha Mahmoud,3 Rasha El-Mahdy2 1Medical Microbiology and Immunology Department, Faculty of Medicine, Damietta University, Damietta, Egypt; 2Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura
Shrief R, El-Ashry AH, Mahmoud R, El-Mahdy R   +3 more
doaj  

Prevalence of carbapenem-resistant Enterobacterales colonisation in hospitalised neonates. [PDF]

S Afr J Infect Dis
Background: Carbapenem-resistant Enterobacterales (CRE) have emerged as major healthcare-associated infection (HAI) pathogens globally with substantial associated mortality and morbidity. Objectives: We conducted a retrospective cohort study to determine the prevalence of rectal CRE colonisation in neonates referred from a central hospital, to a ...
Haumann ME, Bekker A, Geldenhuys C, O'Connell N, Whitelaw A, Esterhuizen T, Dramowski A.   +6 more
europepmc   +4 more sources

A Multicenter Comparison of Carbapenem-Nonsusceptible Enterobacterales and Pseudomonas aeruginosa Rates in the US (2016 to 2020): Facility-Reported Rates versus Rates Based on Updated Clinical Laboratory and Standards Institute Breakpoints

Microbiology Spectrum, 2022
Adoption of revised antimicrobial susceptibility breakpoints is often slow, potentially leading to underreporting of antimicrobial resistance. We compared facility-reported rates of carbapenem nonsusceptibility (NS; intermediate or resistant) with NS ...
Vikas Gupta, Kalvin C. Yu, Jason M. Pogue, Janet A. Watts, Cornelius J. Clancy   +4 more
doaj   +1 more source