Results 71 to 80 of about 25,641 (181)

Antibiotic Susceptibility Profile of Carbapenem Resistant Escherichia Coli and Klebsiella Pneumoniae in Urinary Isolates from a Tertiary Care Hospital: An Observational Study

Journal of Nepal Medical Association
Introduction: Urinary tract infections are common in both hospital and community settings and impose a significant financial burden. Among Enterobacterales, Escherichia coli and Klebsiella pneumoniae are the leading uropathogens.
Gaurav Verma, Shradha Smriti, Rajesh Kumar Dash, Liza Das, Dipti Pattnaik, Nipa Singh, Subhra Snigdha Panda, Sukanta Tripathy   +7 more
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Polymyxin B Intravenous Administration Strategy Guided by Minimum Inhibitory Concentration in Critically Ill Patients With Pulmonary Infection: Insights From PBPK Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.
PBPK/PD modeling and clinical retrospective validation of intravenous polymyxin B in critically ill patients with pulmonary infection. ABSTRACT Intravenous polymyxin B (PMB) is widely used for treating drug‐resistant gram‐negative pneumonia, though its efficacy in pulmonary infections is considered limited.
Shengnan Zhang, Nan Yang, Ruwei Yang, Yuanfang Qin, Tingting Wu, Cuifang Wu, Yueliang Xie, Jingjing Liu, Chun Liu, Qi Pei   +9 more
wiley   +1 more source

Screening haematology patients for carbapenem-resistant Klebsiella pneumoniae [PDF]

Journal of Infection Prevention, 2013
Following a cluster of haematology patients with carbapenem-resistant Klebsiella pneumoniae (CRKP) septicaemia, we initiated screening for rectal carriage of CRKP and multidrug-resistant K. pneumoniae (MDRKP) in this patient group. Haematology inpatients submit a rectal swab once weekly.
Donald, Inverarity, Elizabeth, Kilgour, Caroline, Dunn, Linda, Thomas, Richard, Fox, Lindsay, Mitchell, Pamela, Paterson   +6 more
openaire   +2 more sources

Role of Gram‐Negative Bacterial Infections in Acute‐On‐Chronic Liver Failure

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Acute‐on‐chronic liver failure (ACLF) is a systemic disease characterised by an acute clinical deterioration of pre‐existing liver cirrhosis leading to multiple organ failure due to systemic inflammation. It may be triggered by the translocation of bacteria and bacterial compounds across the gut barrier.
Camilla Cadoli, Volker Müller, Christoph Welsch, Heiko Mühl, Jonel Trebicka, Volkhard A. J. Kempf   +5 more
wiley   +1 more source

Risk Factors for Carbapenem-resistant Klebsiella pneumoniae Infection and Mortality of Klebsiella pneumoniae Infection

Chinese Medical Journal, 2018
Klebsiella pneumoniae (KP) is a pathogen commonly causing nosocomial infection. Carbapenem-resistant KP (CRKP) is more resistant to multiple antimicrobial drugs than carbapenem-susceptible KP (CSKP) isolates. The aim of the present study was to identify the risk factors for CRKP infection and the predictors of mortality among KP-infected adult patients.
Zhe Wang, Ran-Ran Qin, Lei Huang, Li-Ying Sun   +3 more
openaire   +3 more sources

Aminoglycosides for Treatment of Bacteremia Due to Carbapenem-Resistant Klebsiella pneumoniae [PDF]

Antimicrobial Agents and Chemotherapy, 2016
ABSTRACTAminoglycoside treatment of carbapenem-resistant (CR)Klebsiella pneumoniaebacteremia was associated with a 70% rate (23/33) of 30-day survival. Successful treatment was associated with sources of bacteremia amenable to reliable aminoglycoside pharmacokinetics (P= 0.037), acute physiology and chronic health evaluation II (APACHE II) scores of ...
Ryan K, Shields, Cornelius J, Clancy, Ellen G, Press, M Hong, Nguyen   +3 more
openaire   +2 more sources

Systematic review of carbapenem-resistant Enterobacteriaceae causing neonatal sepsis in China

Annals of Clinical Microbiology and Antimicrobials, 2019
Background Carbapenems are β-lactam antibiotics which are used to treat severe infections caused by multidrug resistant Enterobacteriacea. The recent emergence and rapid spread of Enterobacteriaceae resistant to carbapenems is a global concern.
Yijun Ding, Yajuan Wang, Yingfen Hsia, Mike Sharland, Paul T. Heath   +4 more
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Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

An Uncommon Case of Ecthyma Gangrenosum in a Three‐Year‐Old Immunocompetent Child

Clinical Case Reports, Volume 14, Issue 6, June 2026.
The necrotic lesions on day 10. ABSTRACT Ecthyma gangrenosum (EG) is a rare cutaneous finding of Pseudomonas aeruginosa sepsis, typically in immunocompromised patients. We present EG with septic shock in a previously healthy three‐year‐old child who presented with rapidly progressing necrotic eschars and severe neutropenia.
Shobha Maharjan, Nipun Shrestha, Dhruba Shrestha   +2 more
wiley   +1 more source

Diversity of Ceftazidime-Avibactam Resistance Mechanism in KPC2-Producing Klebsiella pneumoniae Under Antibiotic Selection Pressure

Infection and Drug Resistance, 2022
Min Jiang,* Bin Sun,* Yong Huang, Chengyang Liu, Yan Wang, Yanli Ren, Yuhong Zhang, Yunying Wang, Di Mu Department of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China&ast ...
Jiang M, Sun B, Huang Y, Liu C, Wang Y, Ren Y, Zhang Y, Wang Y, Mu D   +8 more
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