Results 181 to 190 of about 28,387 (241)
Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis
European Journal of Organic Chemistry, Volume 29, Issue 32, 24 August 2026.In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley +1 more source
Toddlers and terriers: a One Health partnership to combat antimicrobial resistance
Journal of Small Animal Practice, Volume 67, Issue 9, Page 755-757, September 2026.
M. Prodanuk, F. Emdin
wiley +1 more source
Liposome-encapsulated carbapenems.
Cellular & molecular biology letters, 2002 Zuzanna Drulis-Kawa +4 more
openaire +2 more sources
Therapeutic options for carbapenem-resistant Enterobacteriaceae infections
Virulence, 2017 In recent years, carbapenem resistance among Enterobacteriaceae has dramatically increased and represents an important threat to global health. The optimal therapeutic management of carbapenem-resistant Enterobacteriaceae (CRE) infections has not been ...
Enrico Trecarichi, Mario Tumbarello
exaly +2 more sources
Carbapenem-resistant Pseudomonas aeruginosa and carbapenem use in Japan: an ecological study
Journal of International Medical Research, 2019 Objective This study focused on carbapenem resistance in Pseudomonas aeruginosa and examined potential ecological correlations with carbapenem use in Japan. Methods The proportion of carbapenem-resistant P.
Hiroshi Nishiura
exaly +2 more sources
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Journal of Chemotherapy, 2013
To assess the relative strengths and weaknesses of carbapenems by considering their microbiological, clinical, pharmacokinetics and pharmacokinetic/pharmacodynamic (PK/PD) properties and defining optimal conditions of uses of the new generation of carbapenems.Literature review.Except for ertapenem, the spectrum of activity is similar for all ...
Dominique, Breilh +4 more
openaire +2 more sources
To assess the relative strengths and weaknesses of carbapenems by considering their microbiological, clinical, pharmacokinetics and pharmacokinetic/pharmacodynamic (PK/PD) properties and defining optimal conditions of uses of the new generation of carbapenems.Literature review.Except for ertapenem, the spectrum of activity is similar for all ...
Dominique, Breilh +4 more
openaire +2 more sources
Therapeutic Drug Monitoring, 2003
Antimicrobial resistance is increasing among bacterial pathogens. In particular, organisms producing extended spectrum beta-lactamase enzymes (ESBLs) and AmpC chromosomal beta-lactamase enzymes are resistant to third generation cephalosporins and pose a formidable challenge in the management of seriously ill patients.
Kassa, Ayalew +3 more
openaire +2 more sources
Antimicrobial resistance is increasing among bacterial pathogens. In particular, organisms producing extended spectrum beta-lactamase enzymes (ESBLs) and AmpC chromosomal beta-lactamase enzymes are resistant to third generation cephalosporins and pose a formidable challenge in the management of seriously ill patients.
Kassa, Ayalew +3 more
openaire +2 more sources
Cephalosporins to carbapenems: 1-oxygenated carbapenems and carbapenams
Journal of Medicinal Chemistry, 1990The photo "Wolff" rearrangement of readily available 2-diazoceph-3-em oxides (1) directly affords carbapen-2-ems, allowing a facile entry into a ring system previously accessible only by total synthesis, lengthly semisynthesis or fermentation. The chirality of the cephalosporin is accurately translated into the corresponding carbapenem. The resulting 1-
R L, Rosati +3 more
openaire +2 more sources
Medical Clinics of North America, 1995
Carbapenems are broad-spectrum beta-lactam antibiotics that cover an absolute majority of all bacterial pathogens that possess a cell wall. The only clinically important exceptions are X. maltophilia, E. faecium, and some strains of methicillin-resistant staphylococci and penicillin-resistant pneumococci.
openaire +2 more sources
Carbapenems are broad-spectrum beta-lactam antibiotics that cover an absolute majority of all bacterial pathogens that possess a cell wall. The only clinically important exceptions are X. maltophilia, E. faecium, and some strains of methicillin-resistant staphylococci and penicillin-resistant pneumococci.
openaire +2 more sources
First literature review of carbapenem-resistant Providencia
New Microbes and New Infections, 2018 Providencia species are Gram-negative bacteria that belong to the Enterobacteriaceae family. They have intrinsic resistance to colistin and tigecycline, which makes treatment of the multidrug-resistant strains of Providencia challenging.
Mohammad Abdallah
exaly +2 more sources