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Carbapenem Resistance: A Review [PDF]
Medical Sciences, 2017 Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by ...
Francis S. Codjoe, Eric S. Donkor
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Nature Microbiology, 2021 Infections caused by carbapenemase-producing enterobacteria (CPE) are a major concern in clinical settings worldwide. Two fundamentally different processes shape the epidemiology of CPE in hospitals: the dissemination of CPE clones from patient to ...
Ricardo León-Sampedro +2 more
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Carbapenem resistance in Acinetobacter baumannii , and their importance in hospital‐acquired infections: a scientific review [PDF]
Journal of Applied Microbiology, 2021 Carbapenem is an important therapy for serious hospital‐acquired infections and for the care of patients affected by multidrug‐resistant organisms, specifically Acinetobacter baumannii; however, with the global increase of carbapenem‐resistant A ...
M. Hong Nguyen, Suresh G. Joshi
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Carbapenem resistance in the food supply chain
Journal of Food Protection, 2023 Carbapenems are critically important antibiotic agents because they are considered the “last-resort” antibiotics for treating serious infections. However, resistance to carbapenems is increasing throughout the world and has become an urgent problem. Some
En Huang +3 more
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Journal of Global Antimicrobial Resistance, 2021 Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary directions for Klebsiella pneumoniae, which pose a great threat in clinical settings.
Peng Lan +3 more
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The epidemiology of carbapenem resistance in Acinetobacter baumannii complex in Germany (2014–2018): an analysis of data from the national Antimicrobial Resistance Surveillance system [PDF]
Antimicrobial Resistance and Infection Control, 2021 Carbapenem-resistant Acinetobacter baumannii complex (CRABC) has globally emerged as a serious public health challenge. This study aimed to describe epidemiological trends and risk factors of carbapenem resistance in A.
Dunja Said +5 more
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Mechanisms of Action of Carbapenem Resistance
Antibiotics, 2022 Carbapenem antibiotics are the most effective antimicrobials for the treatment of infections caused by the most resistant bacteria. They belong to the category of β-lactams that include the penicillins, cephalosporins, monobactams and carbapenems. This class of antimicrobials has a broader spectrum of activity than most other beta-lactams antibiotics ...
Aurilio, Caterina +8 more
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Epidemiology and Diagnostics of Carbapenem Resistance in Gram-negative Bacteria
Clinical Infectious Diseases, 2019 Carbapenem resistance in gram-negative bacteria has caused a global epidemic that continues to grow. Although carbapenemase-producing Enterobacteriaceae have received the most attention because resistance was first reported in these pathogens in the ...
Patrice Nordmann, Laurent Poirel
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Trends and correlation between antibacterial consumption and carbapenem resistance in gram-negative bacteria in a tertiary hospital in China from 2012 to 2019 [PDF]
BMC Infectious Diseases, 2021 Background To investigate the trends and correlation between antibacterial consumption and carbapenem resistance in Gram-negative bacteria from 2012 to 2019 in a tertiary-care teaching hospital in southern China. Methods This retrospective study included
Chunhong Liang +5 more
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Nature MicrobiologyEpidemiological knowledge of circulating carbapenem-resistant Klebsiella pneumoniae (CRKP) is needed to develop effective strategies against this public health threat. Here we present a longitudinal analysis of 1,017 CRKP isolates recovered from patients
Fupin Hu, Heng Li, Zhemin Zhou
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