Results 11 to 20 of about 29,439 (214)
Carbapenems, such as imipenem and meropenem, are most often used to treat infections caused by enterobacteria that produce extended-spectrum beta-lactamases, and the emergence of enzymes capable of inactivating carbapenems would therefore limit the options for treatment.
Walther-Rasmussen, J., Høiby, N.
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Carbapenemase-Producing Enterobacteriaceae [PDF]
Carbapenemase-producing Enterobacteriaceae (CPE) were almost nonexistent up to the 1990s, but are today encountered routinely in hospitals and other healthcare facilities in many countries including the United States. KPC-producing Klebsiella pneumoniae was the first to emerge and spread globally and is endemic in the United States, Israel, Greece, and
Doi, Yohei, Paterson, David L.
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In recent years, the number of class D beta-lactamases with carbapenem-hydrolysing properties has increased substantially. Based on amino acid sequence identities, these class D or OXA-type carbapenemases are divided into eight distantly related groups, and they are only remotely related to other class D beta-lactamases.
Walther-Rasmussen, J., Høiby, Niels
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Carbapenemase-producing Klebsiella pneumoniae [PDF]
The continuing emergence of infections due to multidrug resistant bacteria is a serious public health problem. Klebsiella pneumoniae, which commonly acquires resistance encoded on mobile genetic elements, including ones that encode carbapenemases, is a prime example. K. pneumoniae carrying such genetic material, including both blaKPC and genes encoding
Robilotti, Elizabeth, Deresinski, Stan
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Aims and Objectives: Carbapenemase production among clinical isolates of Enterobacteriaceae has been widely reported with prevalence rates ranging from between 2.8% and 53.6%. The aim of this study was to assess the prevalence of carbapenemase production
O O Oduyebo +3 more
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Frequency of Carbapenemase Producing Klebsiella pneumoniae in Makkah, Saudi Arabia [PDF]
Objective: Carbapenemase producing Klebsiella pneumoniae is emerging as an important pathogen worldwide which has alarming clinical threat with serious effects on patients’ outcome.
Mubashir Ahmad Khan, Aftab Faiz
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Comparation of Phenotypic and Genotypic Profile of Carbapenemase Producing Escherichia coli
Carbapenemase-producing Escherichia coli (E. coli) has caused trouble in therapeutic antibiotic selection. Carbapenemase screening procedure in laboratories is usually based on inacurate semi-automatic system.
Silvia Sutandhio +5 more
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BackgroundMultidrug resistant, extremely drug-resistant, pan-drug resistant, carbapenem-resistant, and carbapenemase-producing gram-negative bacteria are becoming more common in health care settings and are posing a growing threat to public health ...
Abera Abdeta +8 more
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Carbapenemases: the Versatile β-Lactamases [PDF]
SUMMARYCarbapenemases are β-lactamases with versatile hydrolytic capacities. They have the ability to hydrolyze penicillins, cephalosporins, monobactams, and carbapenems. Bacteria producing these β-lactamases may cause serious infections in which the carbapenemase activity renders many β-lactams ineffective.
Anne Marie, Queenan, Karen, Bush
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Objective To evaluate the performance of modified carbapenem inactivation method (mCIM) and EDTA carbapenem inactivation method (eCIM) in detection of carbapenemase in Enterobacteriaceae Bateremia.
WANG Yonghong +5 more
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