Results 11 to 20 of about 29,439 (214)

Class A carbapenemases [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2007
Carbapenems, such as imipenem and meropenem, are most often used to treat infections caused by enterobacteria that produce extended-spectrum beta-lactamases, and the emergence of enzymes capable of inactivating carbapenems would therefore limit the options for treatment.
Walther-Rasmussen, J., Høiby, N.
openaire   +2 more sources

Carbapenemase-Producing Enterobacteriaceae [PDF]

open access: yesSeminars in Respiratory and Critical Care Medicine, 2015
Carbapenemase-producing Enterobacteriaceae (CPE) were almost nonexistent up to the 1990s, but are today encountered routinely in hospitals and other healthcare facilities in many countries including the United States. KPC-producing Klebsiella pneumoniae was the first to emerge and spread globally and is endemic in the United States, Israel, Greece, and
Doi, Yohei, Paterson, David L.
openaire   +3 more sources

OXA-type carbapenemases [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2006
In recent years, the number of class D beta-lactamases with carbapenem-hydrolysing properties has increased substantially. Based on amino acid sequence identities, these class D or OXA-type carbapenemases are divided into eight distantly related groups, and they are only remotely related to other class D beta-lactamases.
Walther-Rasmussen, J., Høiby, Niels
openaire   +2 more sources

Carbapenemase-producing Klebsiella pneumoniae [PDF]

open access: yesF1000Prime Reports, 2014
The continuing emergence of infections due to multidrug resistant bacteria is a serious public health problem. Klebsiella pneumoniae, which commonly acquires resistance encoded on mobile genetic elements, including ones that encode carbapenemases, is a prime example. K. pneumoniae carrying such genetic material, including both blaKPC and genes encoding
Robilotti, Elizabeth, Deresinski, Stan
openaire   +2 more sources

Phenotypic determination of carbapenemase producing enterobacteriaceae isolates from clinical specimens at a tertiary hospital in Lagos, Nigeria

open access: yesNigerian Postgraduate Medical Journal, 2015
Aims and Objectives: Carbapenemase production among clinical isolates of Enterobacteriaceae has been widely reported with prevalence rates ranging from between 2.8% and 53.6%. The aim of this study was to assess the prevalence of carbapenemase production
O O Oduyebo   +3 more
doaj   +1 more source

Frequency of Carbapenemase Producing Klebsiella pneumoniae in Makkah, Saudi Arabia [PDF]

open access: yesJournal of Microbiology and Infectious Diseases, 2017
Objective: Carbapenemase producing Klebsiella pneumoniae is emerging as an important pathogen worldwide which has alarming clinical threat with serious effects on patients’ outcome.
Mubashir Ahmad Khan, Aftab Faiz
doaj   +1 more source

Comparation of Phenotypic and Genotypic Profile of Carbapenemase Producing Escherichia coli

open access: yesFolia Medica Indonesiana, 2018
Carbapenemase-producing Escherichia coli (E. coli) has caused trouble in therapeutic antibiotic selection. Carbapenemase screening procedure in laboratories is usually based on inacurate semi-automatic system.
Silvia Sutandhio   +5 more
doaj   +1 more source

Phenotypic characterization of carbapenem non-susceptible gram-negative bacilli isolated from clinical specimens.

open access: yesPLoS ONE, 2021
BackgroundMultidrug resistant, extremely drug-resistant, pan-drug resistant, carbapenem-resistant, and carbapenemase-producing gram-negative bacteria are becoming more common in health care settings and are posing a growing threat to public health ...
Abera Abdeta   +8 more
doaj   +1 more source

Carbapenemases: the Versatile β-Lactamases [PDF]

open access: yesClinical Microbiology Reviews, 2007
SUMMARYCarbapenemases are β-lactamases with versatile hydrolytic capacities. They have the ability to hydrolyze penicillins, cephalosporins, monobactams, and carbapenems. Bacteria producing these β-lactamases may cause serious infections in which the carbapenemase activity renders many β-lactams ineffective.
Anne Marie, Queenan, Karen, Bush
openaire   +2 more sources

Evaluation on clinical application of mCIM and eCIM in detection of cabapenemase from Enterobacteriaceae Bateremia

open access: yesDi-san junyi daxue xuebao, 2020
Objective To evaluate the performance of modified carbapenem inactivation method (mCIM) and EDTA carbapenem inactivation method (eCIM) in detection of carbapenemase in Enterobacteriaceae Bateremia.
WANG Yonghong   +5 more
doaj   +1 more source

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