Results 21 to 30 of about 28,072 (215)
PLoS ONE, 2021 BackgroundMultidrug resistant, extremely drug-resistant, pan-drug resistant, carbapenem-resistant, and carbapenemase-producing gram-negative bacteria are becoming more common in health care settings and are posing a growing threat to public health ...
Abera Abdeta +8 more
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Comparation of Phenotypic and Genotypic Profile of Carbapenemase Producing Escherichia coli
Folia Medica Indonesiana, 2018 Carbapenemase-producing Escherichia coli (E. coli) has caused trouble in therapeutic antibiotic selection. Carbapenemase screening procedure in laboratories is usually based on inacurate semi-automatic system.
Silvia Sutandhio +5 more
doaj +1 more source
Di-san junyi daxue xuebao, 2020 Objective To evaluate the performance of modified carbapenem inactivation method (mCIM) and EDTA carbapenem inactivation method (eCIM) in detection of carbapenemase in Enterobacteriaceae Bateremia.
WANG Yonghong +5 more
doaj +1 more source
Identification and screening of carbapenemase-producing Enterobacteriaceae [PDF]
Clinical Microbiology and Infection, 2012 Carbapenem-hydrolysing β-lactamases are the most powerful β-lactamases, being able to hydrolyse almost all β-lactams. They are mostly of the KPC, VIM, IMP, NDM and OXA-48 types. Their current extensive spread worldwide in Enterobacteriaceae is an important source of concern, as these carbapenemase producers are multidrug-resistant.
Patrice Nordmann +5 more
openalex +4 more sources
Carbapenemases on the move: it’s good to be on ICEs [PDF]
Mobile DNA, 2018 AbstractThe evolution and spread of antibiotic resistance is often mediated by mobile geneticelements. Integrative and conjugative elements (ICEs) are the most abundant conjugativeelements among prokaryotes. However, the contribution of ICEs to horizontal gene transferof antibiotic resistance has been largely unexplored.
João Botelho +4 more
openaire +7 more sources
Microorganisms, 2020 Background: Carbapenemase-producing Enterobacteriaceae (CPE) are an emerging threat in healthcare settings worldwide. Objectives: We evaluated the presence of carbapenemase genes in CPE in a tertiary care university hospital in Tokyo, Japan.
Satoshi Nishida +5 more
doaj +1 more source
Carbapenemases: the Versatile β-Lactamases [PDF]
Clinical Microbiology Reviews, 2007 SUMMARYCarbapenemases are β-lactamases with versatile hydrolytic capacities. They have the ability to hydrolyze penicillins, cephalosporins, monobactams, and carbapenems. Bacteria producing these β-lactamases may cause serious infections in which the carbapenemase activity renders many β-lactams ineffective.
Karen Bush, Anne Marie Queenan
openaire +3 more sources
Detection of carbapenemase production in Enterobacteriaceae and Pseudomonas species by carbapenemase Nordmann–Poirel test [PDF]
Journal of Laboratory Physicians, 2019 Abstract PURPOSE: Multidrug-resistant organisms causing community-acquired and hospital-acquired infections are increasing at a dangerous rate. Carbapenemase-producing Enterobacteriaceae and Pseudomonas species are an important source of concern since these organisms are not only resistant to beta-lactam antibiotics but also show cross ...
Pooja Chandrashaker +5 more
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Pathogens, 2023 (1) Background: Pseudomonas aeruginosa is a Gram-negative bacterium with several intrinsic and acquired antimicrobial resistance mechanisms. The spread of carbapenemase-encoding genes, an acquired mechanism, enables carbapenem resistance in clinical ...
María Guadalupe Martínez-Zavaleta +7 more
doaj +1 more source
The Immaculate Carbapenemase Study [PDF]
Journal of Clinical Microbiology, 2017 ABSTRACT Carbapenemase-producing organisms, or CPOs, are Gram-negative pathogens that produce a transmissible carbapenemase and are typically resistant to most (sometimes all) antibiotics. We now face a global CPO pandemic of high mortality. In this issue of the Journal of Clinical Microbiology , Karlowsky
openaire +3 more sources