Results 211 to 220 of about 24,596 (232)
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Azetidinimines as carbapenemases inhibitors

2017
The present application relates to novel azetidinimine of formula (I). Wherein R1-R6 are as defined in claim 1. The azetidinimine of the invention are useful as antibiotics and as inhibitors of a carbapenemases. The present invention thus further relates totheir use in antibiotic therapies and their methods of synthesis.
Dodd, Robert   +4 more
openaire   +1 more source

The Global Ascendency of OXA-48-Type Carbapenemases

Clinical Microbiology Reviews, 2019
Johann D D Pitout   +2 more
exaly  

Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp.

International Journal of Antimicrobial Agents, 2006
Neil Woodford   +2 more
exaly  

Carbapenemases

Pediatric Infectious Disease Journal, 2010
openaire   +2 more sources

Structural Basis for Carbapenem-Hydrolyzing Mechanisms of Carbapenemases Conferring Antibiotic Resistance

International Journal of Molecular Sciences, 2015
Chang-Ro Lee   +2 more
exaly  

Percurso Hospitalar das carbapenemases

2013
The emergence and spread of carbapenem-resistant bacteria has become a serious threat worldwide. Infections caused by these organisms are associated with high rates of mortality and there are few treatment options. Bacteria have several mechanisms that confer resistance to antibiotics, including production of carbapenemase KPC- 3, one β-lactamase with ...
openaire   +1 more source

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