Results 211 to 220 of about 24,596 (232)
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Azetidinimines as carbapenemases inhibitors
2017The present application relates to novel azetidinimine of formula (I). Wherein R1-R6 are as defined in claim 1. The azetidinimine of the invention are useful as antibiotics and as inhibitors of a carbapenemases. The present invention thus further relates totheir use in antibiotic therapies and their methods of synthesis.
Dodd, Robert +4 more
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The Global Ascendency of OXA-48-Type Carbapenemases
Clinical Microbiology Reviews, 2019Johann D D Pitout +2 more
exaly
Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp.
International Journal of Antimicrobial Agents, 2006Neil Woodford +2 more
exaly
Percurso Hospitalar das carbapenemases
2013The emergence and spread of carbapenem-resistant bacteria has become a serious threat worldwide. Infections caused by these organisms are associated with high rates of mortality and there are few treatment options. Bacteria have several mechanisms that confer resistance to antibiotics, including production of carbapenemase KPC- 3, one β-lactamase with ...
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