Results 11 to 20 of about 38,283 (181)

Carbapenem Resistance: A Review [PDF]

open access: yesMedical Sciences, 2017
Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by ...
Francis S. Codjoe, Eric S. Donkor
doaj   +3 more sources

The Evaluation of Machine Learning Models Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF-MS) Spectra for the Prediction of Antibiotic Resistance in Klebsiella pneumoniae. [PDF]

open access: yesMicrobiologyopen
Machine learning models developed from matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry spectra can rapidly predict antimicrobial resistance in Klebsiella pneumoniae. By transforming routine spectral data into accurate resistance profiles within minutes, this approach could reduce diagnostic delays and support earlier ...
Fordham SME.
europepmc   +2 more sources

Emergence of Tigecycline-Resistant Pseudomonas aeruginosa Harbouring tmexC6D6-toprJ1b From Hospital Sewage in Japan. [PDF]

open access: yesEnviron Microbiol Rep
This study isolated a Pseudomonas aeruginosa strain (KAM950) carrying the tmexCD‐toprJ gene cluster from hospital sewage in Japan. The strain exhibited reduced susceptibility to tigecycline and carbapenems, harboured chromosomal tmexC6D6‐toprJ1b and oprD disruption, and belonged to epidemic clone ST244, emphasising emerging multidrug resistance and the
Maehana S   +10 more
europepmc   +2 more sources

Carbapenem-Resistant Enterobacteriaceae [PDF]

open access: yesClinics in Laboratory Medicine, 2017
Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a major threat. Commonly used antibiotics are generally inactive against CRE. Therefore, timely detection of CRE is of paramount importance. Among CRE, those producing carbapenem-hydrolyzing β-lactamase enzymes (carbapenemase-producing Enterobacteriaceae) are particularly of concern because ...
Alina, Iovleva, Yohei, Doi
  +7 more sources

Parenteral carbapenems [PDF]

open access: yesClinical Microbiology and Infection, 2008
Among the many different structurally distinct classes of beta-lactams, the carbapenem class is regarded as that which is most potent and which has the widest spectrum of antimicrobial activity. Rapidly bactericidal, and demonstrating time-dependent killing, carbapenemes have a spectrum of antimicrobial activity that includes Gram-positive and Gram ...
openaire   +2 more sources

Discrimination between Carbapenem-Resistant and Carbapenem-Sensitive Klebsiella pneumoniae Strains through Computational Analysis of Surface-Enhanced Raman Spectra: a Pilot Study

open access: yesMicrobiology Spectrum, 2022
In clinical settings, rapid and accurate diagnosis of antibiotic resistance is essential for the efficient treatment of bacterial infections. Conventional methods for antibiotic resistance testing are time consuming, while molecular methods such as PCR ...
Wei Liu   +9 more
doaj   +1 more source

Emergence of VIM-6 metallo-beta-lactamase-producing Alcaligenes faecalis clinical isolates in a hospital in India

open access: yesJournal of Infection in Developing Countries, 2013
This item has no abstract. Use the links below to access the full text.
Atul Khajuria   +3 more
doaj   +1 more source

Effect of Differences in the CLSI and EUCAST Criteria on the Interpretation of Enterobacteriaceae Sensitivity to Carbapenems

open access: yesАнтибиотики и Химиотерапия, 2021
Relevance: The two systems for determining the susceptibility of bacteria to antimicrobial drugs, CLSI and EUCAST, are recommended for use in the global system of epidemiological surveillance of antimicrobial resistance of the World Health Organization ...
L. A. Kornoukhova   +3 more
doaj   +1 more source

Biapenem: Clinical and Microbiological Characteristics and the Place of The New Carbapenem In The Treatment of Severe Infections In The Hospital. Clinical Pharmacologists' Point of View

open access: yesАнтибиотики и Химиотерапия, 2022
A new carbapenem antibiotic — biapenem — previously used only in Japan and Southeast Asia, was registered in Russia in 2021. The article analyzes the antimicrobial, pharmacokinetic, and clinical characteristics of biapenem in detail, provides ...
S. V. YAKOVLEV, M. P. SUVOROVA
doaj   +1 more source

The Impact of Acinetobacter baumannii Infections in COVID-19 Patients Admitted in Hospital Intensive Care Units

open access: yesBiology and Life Sciences Forum, 2023
Since the end of 2019, the Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, affecting people worldwide.
Corneliu Ovidiu Vrancianu   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy