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Carbapenem Resistance: A Review [PDF]
Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by ...
Francis S. Codjoe, Eric S. Donkor
doaj +3 more sources
The Evaluation of Machine Learning Models Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF-MS) Spectra for the Prediction of Antibiotic Resistance in Klebsiella pneumoniae. [PDF]
Machine learning models developed from matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry spectra can rapidly predict antimicrobial resistance in Klebsiella pneumoniae. By transforming routine spectral data into accurate resistance profiles within minutes, this approach could reduce diagnostic delays and support earlier ...
Fordham SME.
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Emergence of Tigecycline-Resistant Pseudomonas aeruginosa Harbouring tmexC6D6-toprJ1b From Hospital Sewage in Japan. [PDF]
This study isolated a Pseudomonas aeruginosa strain (KAM950) carrying the tmexCD‐toprJ gene cluster from hospital sewage in Japan. The strain exhibited reduced susceptibility to tigecycline and carbapenems, harboured chromosomal tmexC6D6‐toprJ1b and oprD disruption, and belonged to epidemic clone ST244, emphasising emerging multidrug resistance and the
Maehana S +10 more
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Carbapenem-Resistant Enterobacteriaceae [PDF]
Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a major threat. Commonly used antibiotics are generally inactive against CRE. Therefore, timely detection of CRE is of paramount importance. Among CRE, those producing carbapenem-hydrolyzing β-lactamase enzymes (carbapenemase-producing Enterobacteriaceae) are particularly of concern because ...
Alina, Iovleva, Yohei, Doi
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Among the many different structurally distinct classes of beta-lactams, the carbapenem class is regarded as that which is most potent and which has the widest spectrum of antimicrobial activity. Rapidly bactericidal, and demonstrating time-dependent killing, carbapenemes have a spectrum of antimicrobial activity that includes Gram-positive and Gram ...
openaire +2 more sources
In clinical settings, rapid and accurate diagnosis of antibiotic resistance is essential for the efficient treatment of bacterial infections. Conventional methods for antibiotic resistance testing are time consuming, while molecular methods such as PCR ...
Wei Liu +9 more
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This item has no abstract. Use the links below to access the full text.
Atul Khajuria +3 more
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Relevance: The two systems for determining the susceptibility of bacteria to antimicrobial drugs, CLSI and EUCAST, are recommended for use in the global system of epidemiological surveillance of antimicrobial resistance of the World Health Organization ...
L. A. Kornoukhova +3 more
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A new carbapenem antibiotic — biapenem — previously used only in Japan and Southeast Asia, was registered in Russia in 2021. The article analyzes the antimicrobial, pharmacokinetic, and clinical characteristics of biapenem in detail, provides ...
S. V. YAKOVLEV, M. P. SUVOROVA
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Since the end of 2019, the Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, affecting people worldwide.
Corneliu Ovidiu Vrancianu +6 more
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